Azithromycin medicine composition and preparation method thereof

A technology of azithromycin and composition, which is applied in the field of pharmaceutical preparations, can solve the problems of large flavoring agents, etc., achieve good taste, increase taking compliance, and good compliance
CN110755404AActive Publication Date: 2020-02-07长春雷允上药业有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
长春雷允上药业有限公司
Publication Date
2020-02-07

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Abstract

The invention provides an azithromycin medicine composition and a preparation method thereof. The azithromycin medicine composition comprises medicine granules containing azithromycin, an isolation layer, a taste masking layer and a taste modifying layer, wherein the isolation layer, the taste masking layer and the taste modifying layer sequentially coat the medicine granules in a form of coating.The isolation layer, the taste masking layer and the taste modifying layer of the azithromycin medicine composition are prepared into coats to coat sequentially coat the medicine granules in the formof coating, so that a medicine component release curve is more gentle, and the occurrence of adverse reactions of gastrointestinal tracts can be reduced effectively on the premise that the efficacy and bioavailability are guaranteed. Meanwhile, the azithromycin medicine composition reduces the dosage of a taste modifying agent, is safer to take by children and keeps a good taste.
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Description

technical field

[0001] The invention belongs to the field of pharmaceutical preparations, and relates to an azithromycin pharmaceutical composition and a preparation method thereof, in particular to an azithromycin taste-masking pharmaceutical composition with improved bioavailability and reduced adverse reactions and a preparation method thereof. Background technique

[0002] The absorption rate of drugs in the human body is determined by the dissolution rate. Before being absorbed, the drug components in the solid preparation must go through the process of dissolution and dissolution and then turn into a solution. If the drug is not easily released from the preparation or the dissolution rate of the drug is extremely slow, the absorption rate or extent of the drug ingredients in the preparation is poor, resulting in poor curative effect. On the other hand, if the dissolution rate of the drug with strong pharmacological action and rapid absorption is too fast, obvious adver...

Claims

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