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Antibacterial cleaning composition and wound plaster for wounds

A technology of cleaning composition and bandage, which is applied in the field of medicine and can solve problems such as inconvenient wound treatment

Pending Publication Date: 2020-02-14
GUANGZHOU PHGO BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Wound repair is a complex process involving multi-cells and multi-cytokines. Wound dressings play an important role in treating or repairing wounds. When treating wounds with dressings, the main purpose is to disinfect and sterilize them to avoid further infection of the wound. Then use the body's own healing and repairing ability to wait for the wound to heal. At present, the finished wound repair dressings on the market are in patch or powder form, which are extremely inconvenient for large-area, irregular or difficult-to-treat wounds.

Method used

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  • Antibacterial cleaning composition and wound plaster for wounds
  • Antibacterial cleaning composition and wound plaster for wounds

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A kind of antibacterial cleansing composition for wound, its active ingredient comprises compound egg yolk antibody, compound egg yolk antibody is made by following method:

[0037] The 6 kinds of pathogenic bacteria after the inactivation treatment were calculated according to the mass percentage, 15% of Staphylococcus aureus, 10% of Escherichia coli, 15% of Acinetobacter baumannii, 10% of Pseudomonas aeruginosa, cluster A type B hemolytic chain Mix 40% cocci and 10% Candida albicans to obtain a strain mixture, dissolve the strain mixture, mix the dissolved strain mixture with Freund's adjuvant at a mass ratio of 1:1 and homogenize to obtain a composite antigen, Wherein, the concentration of the strain mixture is 2.5 mg / ml.

[0038] The compound antigen is injected into the chickens for immune enhancement, and the eggs produced by the enhanced immune chickens are collected, separated and purified from the eggs.

Embodiment 2

[0040] An antibacterial cleaning composition for wounds, the active ingredients of which include compound egg yolk antibody and guanidinated chitosan, dimethyl sulfoxide, ginseng oligopeptide and vitamin E, compound egg yolk antibody, guanidinated chitosan, The mass ratio of dimethyl sulfoxide, ginseng oligopeptide and vitamin E is 2:0.4:0.5:1.5:0.07 in sequence.

[0041] The extraction method of the composite egg yolk antibody is the same as the extraction method of the composite egg yolk antibody provided in Example 1.

Embodiment 3

[0043] A kind of antibacterial cleansing composition for wound, its active ingredient comprises compound egg yolk antibody, compound egg yolk antibody is made by following method:

[0044] The 6 kinds of pathogenic bacteria after the inactivation treatment were calculated according to the mass percentage, 16% of Staphylococcus aureus, 14% of Escherichia coli, 15% of Acinetobacter baumannii, 15% of Pseudomonas aeruginosa, cluster A type B hemolytic chain Mix 30% cocci and 10% Candida albicans to obtain a strain mixture, dissolve the strain mixture, mix the dissolved strain mixture with Freund's adjuvant according to the mass ratio of 1:1.3 and homogenize to obtain a composite antigen, Wherein, the concentration of the strain mixture is 2 mg / ml.

[0045] The compound antigen is injected into the chickens for immune enhancement, and the eggs produced by the enhanced immune chickens are collected, separated and purified from the eggs.

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Abstract

The invention provides an antibacterial cleaning composition and wound plaster for wounds, and relates to the field of medicines. Active components of the antibacterial cleaning composition comprise acomposite yolk antibody, wherein the composite yolk antibody is prepared by the following method of mixing staphylococcus aureus with escherichia coli, baumanii, pseudomonas, group A streptococcus and candida albicans, which are inactivated to obtain a bacterial strain mixture, and enabling the bacterial strain mixture to dissolve to prepare composite antigen; and injecting the composite antigeninto a chicken body, performing immunologic facilitation, collecting eggs laid by chickens subjected to supplementary immunization, performing separation from the eggs, and performing refining, so that 6 pathogenic bacteria can be effectively restrained. Besides, the preparation method is simple, and antibodies can effectively exist, are in mutual coordination, are good in activity and good in specific disinfectant effects, and do not influence microecology balance. The wound plaster containing the antibacterial cleaning composition can effectively sterilize and clean the wounds, can prevent the wounds from being infected, and can promote the healing of the wounds.

Description

technical field [0001] The invention relates to the field of medicine, and in particular to an antibacterial cleaning composition and a wound dressing for wounds. Background technique [0002] Wound repair is a complex process involving multi-cells and multi-cytokines. Wound dressings play an important role in treating or repairing wounds. When treating wounds with dressings, the main purpose is to disinfect and sterilize them to avoid further infection of the wound. Then use the body's own healing and repairing ability to wait for the wound to heal. At present, the finished wound repair dressings on the market are in patch or powder form, which are extremely inconvenient for large-area, irregular or difficult-to-treat wounds. [0003] Band-aid is the most commonly used surgical drug in people's life. Band-aid, also known as "hemostatic plaster", has the functions of hemostasis and skin protection. It consists of a long strip of adhesive plaster with a small piece of drug-...

Claims

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Application Information

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IPC IPC(8): A61K39/40A61P17/02A61P31/02A61P31/04A61P31/10A61L15/32A61L15/28A61L15/20A61L15/44A61L15/46A61L26/00A61K31/722A61K31/10A61K38/02A61K31/355
CPCA61K39/40A61K31/722A61K31/10A61K38/02A61K31/355A61P17/02A61P31/02A61P31/04A61P31/10A61L15/32A61L15/28A61L15/20A61L15/44A61L15/46A61L26/0047A61L26/0023A61L26/0066A61L26/0014A61L2300/412A61L2300/404A61L2300/252A61L2300/236A61L2300/216A61K2300/00C08L89/00C08L5/08C08L1/18C08L5/04C08L39/06
Inventor 蒙永祥符美燕农定猛
Owner GUANGZHOU PHGO BIOTECH
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