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Breast milk oligosaccharide composition for improving intestinal flora abundance and fecal odor of infants and application thereof

A technology of breast milk oligosaccharides and intestinal flora, applied in the application, dairy products, milk preparations and other directions, can solve the problems of roughness, unpleasant smell, incomplete digestive function, etc., and achieve the effect of reducing the content and improving the properties.

Pending Publication Date: 2020-02-28
INNER MONGOLIA YILI INDUSTRIAL GROUP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Due to the young age of infants, the digestive function is not perfect enough. If the feeding is too frequent, or if the milk powder is too thick during artificial feeding, it will cause indigestion in infants and young children.
Moreover, the protein content in infant formula powder is too much at present, the protein neutralizes the gastric acid in the stomach, reduces the acidity of gastric juice, so that the protein cannot be fully digested and absorbed, and the microbial flora in the intestinal cavity of infants is not yet perfect , the catabolism of bacteria is slow, it is easy to cause dry and rough stools of infants and young children, often with unpleasant feces odor

Method used

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  • Breast milk oligosaccharide composition for improving intestinal flora abundance and fecal odor of infants and application thereof
  • Breast milk oligosaccharide composition for improving intestinal flora abundance and fecal odor of infants and application thereof
  • Breast milk oligosaccharide composition for improving intestinal flora abundance and fecal odor of infants and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] This example provides multiple groups of formula milk powder for infants and young children, which are respectively prepared into milk according to the composition of raw materials given in Table 2 and prepared by spray drying.

[0029] Table 2 Composition of spray-dried milk liquid of infant formula milk powder

[0030]

[0031]

[0032] Continued Table 2

[0033]

[0034]

[0035] Continued Table 2

[0036]

[0037]

Embodiment 2

[0039] Combination 1, combination 4 and combination 7 were used to gavage SD suckling mice. Forty suckling mice (14 days old, average body weight 30.27±1.51g) were divided into four groups, 12 in each group. FL group: infant formula feeding of combination 1; FL+SL group: infant formula feeding of combination 4; FL+SL+LNT group: infant formula feeding of combination 7; group D: formula without adding oligosaccharides. The standard of milk powder is 65g milk powder / 15mL water. Feed once every 4 hours, 1 mL each time. The entire feeding process lasted 7 days. The temperature of the feeding environment for suckling mice was kept at about 23°C, kept clean, and black and white cycled for 12 hours. The feeding process should follow the experimental rules. The status of the mice was observed every day, and the weight was weighed and recorded.

Embodiment 3

[0040] The mensuration of skatole content in the ight soil of embodiment 3

[0041] Preparation of Standards

[0042]Accurately weigh 55.4 mg of skatole and 37.6 mg of indole, dissolve them in methanol, and place them in 25 mL brown volumetric flasks respectively. This is the standard stock solution of skatole and indole. Each stock solution was diluted in 3 stages to prepare mixed standard series working solutions with skatole and indole concentrations of 27.7, 55.4, 110.8, 221.6, 332.4 μg / L and 11.3, 22.6, 45.2, 90.4, 135.6 μg / L, respectively. Make a linear regression test. In the actual determination of the samples, the mixed standard working solutions with concentrations of skatole and indole of 110.8 μg / L and 45.2 μg / L were taken as external standard method for quantification.

[0043] sample handling

[0044] Weigh 0.1g of rat feces, add 5mL of methanol, freeze the mixture at -20°C for 30min, centrifuge at 3000g for 10min, and pass the supernatant through activated co...

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Abstract

The invention provides a breast milk oligosaccharide composition for improving intestinal flora abundance and fecal odor of infants and application thereof. The breast milk oligosaccharide compositioncomprises 2'-fucosyllactose and / or 3'-fucosyllactose, and galactooligosaccharides. The invention also provides application of the breast milk oligosaccharide composition in improving intestinal floraabundance and fecal odor of infants. The invention also provides infant formula milk powder containing the breast milk oligosaccharide composition. The composition according to the invention has a plurality of breast milk oligosaccharides in different ratios, can increase the abundance of actinomycetes and firmicutes in intestinal microflora of infants, increase the number of bifidobacteria and lactic acid bacteria of infants and change the composition of intestinal flora, and can reduce the pH value of intestines and the contents of indole and skatole, reduce the contents of indole and skatole in infant feces, improve the character of infant feces, and reduce the concentration of peculiar smell compounds.

Description

technical field [0001] The invention relates to a breast milk oligosaccharide composition for improving the intestinal flora abundance and stool odor of infants and an application thereof, belonging to the technical field of dairy products. Background technique [0002] Because infants are young and their digestive function is not perfect enough, if they are fed too frequently, or if artificial feeding, milk powder is too thick, it will cause indigestion in infants. Moreover, the protein content in infant formula powder is too much at present, the protein neutralizes the gastric acid in the stomach, reduces the acidity of gastric juice, so that the protein cannot be fully digested and absorbed, and the microbial flora in the intestinal cavity of infants is not yet perfect , The catabolism of bacteria is slow, which can easily cause dry and rough stools of infants and young children, often with an unpleasant fecal odor. [0003] The smell of stool is caused by the products o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23C9/20A23C9/16A23C9/156
CPCA23C9/203A23C9/16A23C9/156
Inventor 刘宾孔小宇畅鹏飞刘彪李威
Owner INNER MONGOLIA YILI INDUSTRIAL GROUP CO LTD
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