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Compound preparation for discharging lead

A compound preparation, myricetin technology, applied in the field of health food, can solve the problem of high lead content, achieve the effects of reducing lead content, good lead discharge effect, and no toxic and side effects

Pending Publication Date: 2020-07-03
NORTHWEST UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Currently there is no effective solution to the problem of high lead levels in the blood

Method used

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  • Compound preparation for discharging lead
  • Compound preparation for discharging lead
  • Compound preparation for discharging lead

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 1

[0018] A compound preparation for lead removal, the preparation is prepared into tablets, and its components and contents are: the main components of every 100g compound preparation: 341mg myricetin, 1568mg calcium element, 198mg zinc element and 257mg iron element; Add 7g of dextrin, 10g of powdered sugar, 4g of povidone, 5g of magnesium stearate and 71.636g of starch as raw materials, mix evenly, granulate, press into plain tablets, and coat to obtain tablets.

specific Embodiment 2

[0020] A compound preparation for lead removal, the preparation is prepared into hard capsules, its components and content are: the main components of every 100g compound preparation: 341mg myricetin, 1568mg calcium element, 198mg zinc element and 257mg iron element; Add 7g of dextrin, 10g of powdered sugar, 4g of povidone, 5g of magnesium stearate and 71.636g of starch to the above raw materials, mix them evenly, and fill them into the capsule shell by hard capsule automatic filling equipment to make hard capsules.

experiment example

[0022] This experimental example is used to test the lead-expelling effect of the compound preparation with lead-expelling function of Example 1 on lead-poisoned mice.

[0023] 1) Experimental materials and equipment

[0024] Five-week-old healthy male ICR mice were purchased from the Experimental Animal Center of Xi'an Jiaotong University School of Medicine, Shaanxi Province.

[0025] Reagents: ultrapure water, MDA, SOD and GSH kits, lead acetate, etc.

[0026] Instruments: plasma emission spectrometer, microwave digestion instrument, electronic balance, microplate reader, desktop centrifuge, etc.

[0027] 2) Experimental design

[0028] Mice were randomly divided into 3 groups, 10 in each group, and treated as follows.

[0029] Blank control group: give mice 0.5% carboxymethylcellulose sodium (CMC-Na) solution, and give deionized water two hours later;

[0030] Model group: give mice 0.5% CMC-Na solution, and give 50mg / kg lead acetate solution two hours later;

[0031] ...

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PUM

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Abstract

The invention discloses a compound preparation for discharging lead. The compound preparation contains the following chemical components: 320-360mg of myricetin, 1400-1600mg of calcium element, 170-200mg of zinc element and 260-280mg of iron element. The components in the compound preparation provided by the invention can generate a synergistic lead discharging effect, and trace elements such as calcium, iron, zinc and the like are simultaneously supplemented. In addition, the compound preparation for discharging lead is safe and has no toxic or side effect.

Description

technical field [0001] The invention relates to the technical field of health food, in particular to a compound preparation for lead removal. Background technique [0002] Lead has been used by humans for at least seven thousand years. It has high corrosion resistance, good ductility, high density, low melting point, and easy recycling, so it is widely used in battery manufacturing, welding tanks, cable ceramics, crystals, pipes, and paints. Lead is a stable, non-degradable, non-essential heavy metal pollutant that can accumulate in the environment for a long time. Therefore, the extensive use of lead has caused extensive environmental pollution, and has toxic effects on various tissues, organs and systems of animals and humans. Long-term exposure will cause increased lead levels in the blood, resulting in behavioral, respiratory and visual disorders, leading to developmental Retardation, blood, immune, liver, kidney and reproductive dysfunction. At present, there is stil...

Claims

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Application Information

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IPC IPC(8): A23L33/105A23L33/16A61K33/30A61P39/02A61K31/352A61K33/06
CPCA23L33/105A23L33/16A61K31/352A61K33/06A61K33/30A61P39/02A23V2002/00A23V2250/2116A23V2200/30A23V2250/1578A23V2250/1592A23V2250/1642A61K2300/00
Inventor 曹炜王倩赵浩安程妮
Owner NORTHWEST UNIV
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