23 results about "Visual Disorders" patented technology

An ophthalmic lens configured to correct and / or treat at least one condition of the eye (e.g., presbyopia, myopia, hyperopia, astigmatism, binocular vision disorders, night vision image quality, and / or visual fatigue syndrome) comprising: a base power profile; and at least one pulse selected to modify the base power profile.

The use of α-ketoglutaric acid in the preparation of a drug for preventing and treating demyelination-related diseases. The α-ketoglutaric acid or a derivative thereof is used for preventing and / or treating myelin sheath defects in demyelination-related diseases, such as demyelinating diseases, amyotrophic lateral sclerosis, Huntington's disease, hypomyelinating leukodystrophy, Alzheimer's disease, Parkinson's syndrome and diabetes-related visual impairment, and can promote myelin sheath generation, regeneration or repair, and improve the immune microenvironment in the lesion area.

A user's visual disorders can be treated via a virtual reality (VR) system, which can include a VR headset in electronic communication with a computing device. The computing device causes vision tests to be displayed on the VR headset. Using varying combinations of eye-tracking sensors, eye-tracking cameras, motion-tracking sensors, handheld devices, and microphones, the VR headset can collect data about the user as she completes the vision tests. Using the data collected by the VR headset, the computing device can evaluate the user for various visual disorders and develop a personalized vision therapy plan for the user. Optionally, advanced algorithms in the computing device dynamically alter the vision therapy plan based on the user's performance and the progression of her visual disorders.

The present inventive concept provides methods of determining whether a subject has cortical or cerebral visual impairment (CVI) as well as determining whether the subject has a traumatic brain injury thereby allowing treatment for these conditions. The present inventive concept also provides a standardized method for assessing pediatric or adolescent visual acuity.

The invention relates to the field of intelligent question and answer calculation, in particular to a visual impairment group vertical field multi-modal intelligent question and answer method based on a neural network, which comprises the following steps: S1, knowledge base preprocessing: standardizing a knowledge base, including performing information extraction, semantic understanding and multi-modal dialogue on texts in the knowledge base; s2, performing structured processing on the multi-mode vertical domain knowledge base; s3, generating detailed description information from the knowledge of the picture modality through an image-text big model; s4, forming a document by using the decomposed subject-predicate-object structure and the fixed complementary structure to replace the original characters, and identifying the document by using an ID (Identity); s5, collecting related attributes of the entities according to the query ID, and generating a candidate attribute list; and S6, according to the score, determining an attribute relationship closest to the question, and taking out an attribute value of the closest attribute relationship to complete answering. The method has the advantages that more accurate and personalized multimode vertical domain knowledge introduction question and answer service can be provided for visually impaired people to obtain information.

The pneumatic curtain wall comprises a connecting mechanism, a main shaft of the connecting mechanism is arranged in a cylindrical connecting base in a penetrating mode and provided with an arc-shaped groove, and a torsional spring is arranged on the main shaft in a sleeving mode so as to provide elastic damping when two connecting blades rotate relatively. The angle limiting mechanism drives clamping nails inserted into the through holes of the blades to be clamped into the arc-shaped grooves through reset springs so as to limit the rotation range. According to the pneumatic curtain wall, the problems of visual disorder caused by free rotation and noise and fatigue cracking caused by lack of buffering are effectively solved through cooperative cooperation of torsional spring damping and staple bolt limiting; the elastic damping is used for absorbing impact energy, the service life is prolonged, and it is ensured that the curtain wall presents the uniform and controlled rhythm dynamic visual effect through precise limiting.

Provided is a polypeptide capable of dissolving protein aggregates. Also provided is a method of treating a phase separation associated diseases, such as phase separation associated visual disorders (e.g., cataracts) using the polypeptide provided herein.

The invention relates to apparatuses and methods for providing control data for an ophthalmological laser (12) of a treatment apparatus (10). The method includes ascertaining (S10) correction data for a planned refraction correction of a visual disorder of a cornea (16) from predetermined examination data, wherein the correction data includes a correction for a sphere value, a cylinder value and an axis value; determining (S12) adapted correction data based on a nomogram and the ascertained correction data, wherein the correction of the sphere value and / or the cylinder value and / or the axis value is adapted to the used treatment apparatus (10) by the nomogram, such that a refraction correction with the adapted correction data corresponds to the planned refraction correction, wherein the nomogram is ascertained by preceding treatment results with identical treatment apparatuses; and providing (S14) the control data, which is based on the adapted correction data.

The present disclosure provides a variant of a phase separation reversing polypeptide. Also provided is a method of treating phase separation-related diseases, such as phase separation-related visual disorders, age-related macular degeneration, and neurodegenerative diseases, using the variant of the phase separation reversing polypeptide provided herein.

A method for providing control data for an eye surgical laser is disclosed. A control device ascertains a lenticule geometry of a lenticule to be separated from predetermined visual disorder data of a human or animal eye. The control device ascertains a correction value for compensating for a deformation of the lenticule, which is generated by at least one contact element of the treatment apparatus. The control device ascertains a deformation geometry of the lenticule, wherein a deformation refractive power value is calculated depending on the refractive power value to be corrected and the correction value. A deformation diameter is calculated depending on a lenticule diameter and the correction value. The control device provides control data for controlling the eye surgical laser, which uses the deformation geometry for the separation of the lenticule.

The invention relates to the technical field of visual impairment simulation, in particular to a visual impairment dynamic evolution simulation system and method. Multi-modal medical image data of a patient is collected and subjected to preprocessing and focus positioning, an individual visual pathway fiber bundle is constructed by adopting a deterministic fiber tracking algorithm based on diffusion tensor imaging data, non-rigid registration is performed on the individual fiber bundle and a standard visual pathway template, a local deformation field is calculated, and the focus positioning accuracy is improved. Based on a local deformation field, analyzing a spatial geometrical relationship between a focus mask and each section of nerve fiber to obtain an individualized three-dimensional visual pathway model and an SDI scoring matrix of each section corresponding to the individualized three-dimensional visual pathway model, and judging a damaged pathway section and a typical visual field defect mode matched with the damaged pathway section in degree; according to the method, individualized visual simulation of a patient is realized, a visual dynamic evolution prediction model is constructed by utilizing diffusion Transform, and dynamic evolution of visual impairment is realized.

The invention relates to a method for providing control data for an ophthalmological laser (12) of a treatment apparatus (10). By a control device (18), determining (S10) corneal parameters of an anterior surface (24) of a cornea (16) from predetermined examination data; determining (S12) an epithelial map of an epithelial layer (26) of the cornea (16) from the predetermined examination data, wherein a thickness of the epithelial layer (26) is provided in the epithelial map; calculating (S14) a stromal wavefront map depending on the determined corneal parameters of the anterior surface (24) of the cornea and the determined epithelial map; determining (S16) correction data for correcting a visual disorder based on the stromal wavefront map; and providing (S18) the control data, which includes the correction data determined based on the stromal wavefront map are effected.

A method for providing control data of an eye surgical laser is disclosed. A control device ascertains a lenticule geometry of the lenticule to be separated from predetermined visual disorder data of a human or animal eye. The lenticule geometry is defined by means of a refractive power value to be corrected and a lenticule diameter. The control device ascertains a correction value for compensating for a deformation of the lenticule, which is generated by at least one contact element of the treatment apparatus. The control device ascertains a deformation geometry of the lenticule, wherein the deformation geometry is defined by means of the refractive power value and a deformation diameter. The deformation diameter is calculated depending on the lenticule diameter and the correction value, and provides control data for controlling the eye surgical laser, which uses the deformation geometry for the separation of the lenticule.

This invention provides an ophthalmic composition for treating and / or preventing visual impairment caused by changes in the structure of the eye's lens, specifically involving alterations in the proteins that form the lens. The ophthalmic composition comprises a combination of a therapeutically effective amount of a polyphenolic compound and a terpene compound, or their salts or crystalline forms, requiring low doses of the bioactive compound to treat the disease with reduced frequency of administration. In particular, the ophthalmic composition of this invention can be used to treat and reverse visual impairments caused by changes in lens structure, such as cataracts, by reversing the lens opacity caused by the disease.

Provided is a class of compounds represented by formula (I), or prodrugs, tautomers, stereoisomers, solvates, isotopic derivatives or pharmaceutically acceptable salts thereof. The compounds have SHP2 kinase inhibitory effects and can be used to treat and / or prevent diseases, disorders and conditions mediated by SHP2 activity, such as tumors, cancer, cancer metastasis, cardiovascular diseases, immune disorders or visual disorders.

Methods and systems for assessing and / or treating visual disorders, such as discorder in accommodative ability and / or vergence ability, of a person are provided. Assessment and training exercises can be performed utilizing a computerized system in communication with a head-mountable display (HMD), such as a virtual or augmented reality display, which can display visual targets at various vergence and accommodative demands. Lenses, such as inverted bifocal lenses, may be used in combination with the HMD to mimic natural accommodative demand during viewing or to enable assessment and treatment of accommodation disorders. Corrective factors can be calculated and utilized for generation of visual targets to account for lens characteristics and / or interpupillary distance mismatch. Accommodation and vergence responses can be tracked during display of the visual targets at the various demands, and assessed in comparison to normalized values for assessment of vision disorders or utilized to track progress of user in treatment of a vision disorder.

Method for providing control data for an ophthalmic surgical laser, wherein the method comprises the following steps performed by a control device (20): - Determining refractive error data describing a degree of refractive error of a human or animal eye (40) (S1), - Determining an actual geometry of a correction area (32) of a cornea (17) of the eye (40), which describes three-dimensional dimensions of the correction area (32) of the cornea (17) (S2), - based on the determined refractive error data and the determined actual geometry: Determining a target geometry of the correction area (32) that describes a reduction component (44) of the correction area (32) with a corneal thickness reduced compared to the actual geometry, and / or a thickening component (42) with a corneal thickness increased compared to the actual geometry; wherein the determined target geometry fulfills a predefined refractive error reduction criterion that specifies suitability for reducing the degree of refractive error (S3), - Specifying the angle of rotation and the axis of rotation (31) depending on: a) a result of a comparison of the determined actual geometry with the determined target geometry, and / or b) the determined visual impairment data (S5), - based on the determined actual geometry: Determining interfaces (14, 16) of a lenticel (12) within the correction area (32), which extends at least partially over the correction area (32), wherein a portion of the lenticel (12) is designed such that, when the lenticel (12) is rotated (D) into the thickening portion (42) about the specified axis of rotation (31) passing through the cornea (17) and about the specified angle of rotation, it transforms the correction area (32) from the determined actual geometry into the determined target geometry (S4), - Defining at least one incision path as access for an instrument to rotate the lenticule (12), which extends from a predetermined incision site on an outer surface of the cornea (17) to one of the defined interfaces (14, 16) (S7), and - Providing control data that describe the determined interfaces (14, 16) for forming the lenticel (12), the at least one determined incision path, the specified axis of rotation (31) and a rotation of the lenticel (12) about the specified angle of rotation (S6).

The invention discloses a display exception processing method and device, equipment and a storage medium. The method comprises the steps that the collection time of sensing signals corresponding to multiple visual objects is obtained, the multiple visual objects are displayed on a vehicle-mounted display interface, and the visual objects are obtained through 3D rendering based on the corresponding sensing signals; according to the collection time sequence, respectively calculating the duration difference between the collection time corresponding to each visual object and the current time; and determining the visual object of which the duration difference exceeds a preset duration threshold as a target visual object, and removing the target visual object from the vehicle-mounted display interface. According to the method, the abnormally displayed visual object can be removed from the vehicle-mounted display interface in time, so that the problems of interface lagging, visual disorder and the like caused by display retention are avoided, the real-time response capability of a vehicle-mounted display system is improved, and the visual experience of a user is also enhanced.

The invention relates to a method for providing control data for an ophthalmic laser (12) of a treatment device (10). By means of the control device (18), it is achieved that: corneal parameters of an anterior surface (24) of the cornea (16) are determined (S10) as a function of predetermined examination data; determining (S12) an epithelium map of an epithelium layer (26) of the cornea (16) on the basis of the predetermined examination data, wherein a thickness of the epithelium layer (26) is provided in the epithelium map; calculating (S14) a stromal wavefront map from the determined corneal parameters of the anterior surface (24) of the cornea and the determined epithelium map; determining (S16) correction data for correcting the visual impairment based on the matrix wavefront map; and providing (S18) control data comprising correction data determined based on the matrix wavefront map.

The present application relates to ophthalmic compositions comprising levodopa, an antioxidant, and an aqueous carrier. Disclosed are compositions comprising levodopa and an antioxidant for inhibiting the development or progression of visual disorders, including visual disorders associated with diabetic retinopathy or Parkinson's disease, as well as myopia.

The invention relates to a device and a method for providing control data for an ophthalmic laser (12) of a treatment device (10). The method comprises: determining (S10) correction data for a planned refractive correction of a visual disorder of the cornea (16) from predetermined examination data, wherein the correction data comprises corrections of spherical, cylindrical and axial values; ascertaining (S12) adapted correction data from the column map and the ascertained correction data, the correction of the spherical and / or cylindrical and / or axial values being adapted by means of the column map to the used treatment device (10) such that the refractive correction having the adapted correction data corresponds to the planned refractive correction; wherein the column map is determined by previous treatment results using the same treatment device; and providing (S14) control data based on the adapted correction data.

This invention relates to the field of ocular visual function rehabilitation and neuroelectrophysiological regulation technology. The invention discloses an ocular photostimulation matrix device, comprising: a housing; a display screen, power socket, power switch, and output socket disposed on the housing; a circuit board, a specific medical transformer, and a card reader chip assembly disposed inside the housing; and an output component connected to the output socket. This device is a non-invasive ocular rehabilitation device, breaking through the limitations of traditional vision correction and nerve repair technologies. Using 8-14Hz alpha waves as its core, it directly targets the core link of the visual nerve-central nervous system, fundamentally repairing visual conduction pathway disorders. It is non-invasive, has no usage restrictions, and is suitable for various visually impaired individuals. The device is easy to operate and can be used daily. It can induce endogenous light for preliminary fundus screening and can also address vision repair and brain nerve regulation. Supporting accessories further enhance the conditioning effect and device stability.

The present invention discloses an obstacle detection method and a readable medium for assisting navigation for the visually impaired, belonging to the technical field of target detection. The method inputs an obstacle image to be detected into an obstacle detection network for regression and classification tasks; a feature weighting module in the obstacle detection network weights the extracted features after the backbone network, and an adaptive bottleneck module is integrated in KAN‑PAFPN, which realizes effective fusion and optimization of features, thereby improving the robustness of the model in complex backgrounds, especially for the detection of occlusions and small targets. The enhanced feature attention head is responsible for the final target classification and regression tasks. By introducing a convolutional block attention module CBAM and a transposed convolution module, the accuracy of the model in target position regression and category judgment is enhanced. The readable medium stores computer instructions, which, when executed, cause the computer to execute the steps of the above-mentioned obstacle detection method for assisting navigation for the visually impaired.