214 results about "Methods treatment" patented technology

This invention provides a shunt for implantation between the anterior chamber of the eye and the epithelial-lined space through the frontal sinus bone of a patient for the treatment of glaucoma. The shunt includes a tube having a length sufficient to span the distance between the anterior chamber of the eye and the epithelial-lined space of the patient, the tube having an open anterior chamber end and a closed epithelial-lined space end, and a seal device associated with the tube between the anterior chamber and epithelial-lined space ends, for sealing a hole in the frontal sinus bone, and for anchoring the tube against movement from the frontal sinus bone. The shunt also includes a fluid pressure openable valve in the tube, located at or near the epithelial-lined space sinus end, allowing for controlled flow of aqueous humor through the tube when implanted. The invention also extends to a method of treating glaucoma in a patient by surgically implanting the shunt between the anterior chamber of the eye and the frontal sinus.

Disclosed are surgical tools, tool sets and methods for percutaneously accessing and preparing treatment sites within the spine for subsequent treatment procedures. The treatment site may be an inter-vertebral motion segments in the lumbar and sacral regions of the spine. The tool set may comprise introducer tools and bone dilators for accessing and tapping into a targeted site, such as, for example, the anterior surface of the S1 vertebral body. The tool set may also comprise cutters and extractors for preparing the treatment site for subsequent treatment procedures. The tool set may additionally comprise a bone graft inserter, an exchange system, and / or a temporary distraction tool for further preparing the treatment site for subsequent treatment procedures.

A simultaneous multifocal contact lens for correcting vision acuity of an individual is disclosed. The contact lens comprises a central region radially surrounded by at least one far vision focal region and at least one near vision focal region, wherein a near vision additional correction of the at least one near vision focal region is overcorrected by at least 10% with respect to the near vision additional correction prescribed for the

This invention provides a shunt for implantation between the anterior chamber of the eye and the epithelial-lined space through the frontal sinus bone of a patient for the treatment of glaucoma. The shunt includes a tube having a length sufficient to span the distance between the anterior chamber of the eye and the epithelial-lined space of the patient, the tube having an open anterior chamber end and a closed epithelial-lined space end, and a seal device associated with the tube between the anterior chamber and epithelial-lined space ends, for sealing a hole in the frontal sinus bone, and for anchoring the tube against movement from the frontal sinus bone. The shunt also includes a fluid pressure openable valve in the tube, located at or near the epithelial-lined space sinus end, allowing for controlled flow of aqueous humor through the tube when implanted. The invention also extends to a method of treating glaucoma in a patient by surgically implanting the shunt between the anterior chamber of the eye and the frontal sinus.

Provide herein are fusion polypeptides that comprise a CD47 extracellular domain or a variant thereof that is fused to a Fc polypeptide. The fusion polypeptides are useful for treating an immunological disease or disorder in a subject according to the methods described herein. The fusion polypeptides are capable of suppressing immunoresponsiveness of an immune cell, inhibiting production of proinflammatory cytokines, including inhibiting immune complex-induced production of cytokines.

Devices and methods are provided for applying vacuum near to devices for delivering treatments to tissue adjacent a body cavity, effective to draw adjacent tissue near to such devices and to enhance treatment of the tissue. Body cavities include natural body cavities and cavities remaining after removal of tissue such as cancerous tissue. A device may include an inner balloon assembly with an inflation conduit. A sheath assembly having a fluid-permeable sheath wall may enclose the inner balloon assembly. Vacuum applied to the space between the sheath and the inner balloon is useful to draw tissue into contact with the device, improving treatment effectiveness. Methods for treating tissue with such devices and systems are also provided. Treatments may include providing radioactive material for radiation treatment, providing chemotherapeutic material for chemotherapy, providing thermal treatment, and combinations thereof. Systems may include devices of the invention and a vacuum source.

The small molecule profiles of cells are compared to identify small molecules which are modulated in altered states. Cellular small molecule libraries, methods of identifying tissue sources, methods for treating genetic and non-genetic diseases, and methods for predicting the efficacy of drugs are also discussed.

The small molecule profiles of cells are compared to identify small molecules which are modulated in altered states. Cellular small molecule libraries, methods of identifying tissue sources, methods for treating genetic and non-genetic diseases, and methods for predicting the efficacy of drugs are also discussed.

A system for treating an occlusive region of a blood vessel comprises: a catheter outer tube forming a lumen for inflation of a centering balloon; a catheter inner tube lined with either internal spiral threads or point slots to assist controlled guidewire movement; and a rotatable guidewire that may be solid or hollow. The guidewire comprises a rotatable body and a proximal shaft. The rotatable body has two components: a distal rotating head and a proximal rotating shaft, wherein these components are of equal length and the rotating shaft resides within the proximal shaft. Linear force applied to the proximal shaft will result in the rotational guidewire tip puncturing cutting through an occlusion. In an alternative embodiment, the guidewire rotatable body comprises two mechanical rings and a compression spring, wherein when the spring is released via depression of a button, the guidewire tip drills through an occlusion.

The small molecule profiles of cells are compared to identify small molecules which are modulated in altered states. Cellular small molecule libraries, methods of identifying tissue sources, methods for treating genetic and non-genetic diseases, and methods for predicting the efficacy of drugs are also discussed.

The invention discloses a textile dyeing wastewater advanced treatment recycling technology. The technology comprises the following steps: filtering to remove textile fibers; cooling; neutralizing, degrading organic matters and decomposing, replacing or degrading (cracking) the chormophoric groups of the organic matters to reduce the chroma of the wastewater; performing biochemical treatment with the biomembrane; precipitating to ensure that the precipitated sludge enters a sludge treatment system and the supernatant enters a flocculation pool; performing chemical treatment, namely adding a medicament in the flocculation pool to remove the suspended matter (SS), CODcr (chemical oxygen demand), BOD (biochemical oxygen demand) and chroma of the water; performing secondary precipitation to ensure that the free SS is precipitated and the wastewater is decolored further; separating to remove and degrade the chloride ions of the reuse water; performing secondary biochemical treatment to further reduce the concentrations of the SS, CODcr and BOD in wastewater; performing ozone oxidation treatment, decoloring, degrading organic matters; performing chemical treatment to remove insoluble dye materials and SS and reduce the COD and chroma; and performing secondary filtration, and forming an ozone / activated carbon system to ensure that the hydroxyl radicals of activated carbon are used and the organic reaction in wastewater is adopted to decolor and degrade organic matters. The invention overcomes the defects of the existing physical method, chemical method and chemical method treatment technologies; and the technology has been used in many enterprises, and the good treatment effects are obtained.

The small molecule profiles of cells are compared to identify small molecules which are modulated in altered states. Cellular small molecule libraries, methods of identifying tissue sources, methods for treating genetic and non-genetic diseases, and methods for predicting the efficacy of drugs are also discussed.

The invention discloses a preparation method of a high-specific-surface-area porous nitrogen-doped graphitizing carbon nanomaterial, relating to a preparation method of a carbon material and aiming at solving the problems of small specific surface area, low nitrogen content, low productivity, poor graphitizing degree and high cost of the nitrogen-doped graphitizing carbon nanomaterial prepared by the prior art. The preparation method comprises the steps of: I. preparing a complex; II. curing and carbonizing the complex; and III. carrying out acid leaching method treatment, and drying. Compared with an existing nitrogen-doped graphitizing carbon nanomaterial, the prepared high-specific-surface-area porous nitrogen-doped graphitizing carbon nanomaterial has the advantages that the graphitizing degree is improved, the nitrogen content is increased, and the specific surface area is obviously increased, and the high-specific-surface-area porous nitrogen-doped graphitizing carbon nanomaterial has obvious pore diameter distribution. The preparation method is used for preparing the high-specific-surface-area porous nitrogen-doped graphitizing carbon nanomaterial.

One aspect of the present invention relates to a method of treating of drug addiction or drug dependence in a mammal, comprising the step of administering to a mammal in need thereof a therapuetically effective amount of a heterocyclic compound, e.g., a 3-substituted piperidine. In a preferred embodiment, the method of the present invention treats cocaine addiction or methamphetamine addiction.

A method for reducing the recurrence of a resectable malignant tumor includes administering an immunostimulatory dosage of an α-interferon composition, then surgically resecting the malignant tumor. A method for treating a human patient having a non-resectable malignant tumor includes administering an immunostimulatory dosage of an α-interferon composition to the patient and treating the patient with effective non-surgical medical methodologies to diminish the tumor. An article of manufacture combines an α-interferon composition within a packaging material and a package label or insert indicating that administration of an immunostimulatory dosage of an α-interferon composition followed by surgical resection of a malignant tumor can be effective for treating a human patient having the malignant tumor.

Pharmaceutical compositions comprising at least one alpha2-adrenergic agonist or baclofen and at least one alpha1-adrenergic agonist are disclosed. Pharmaceutical compositions comprising tizanidine and modafinil are disclosed. Methods for reducing somnolence, sleepiness, lethargy, dizziness, drowsiness, somnolence, tiredness, lightheadedness, increased weakness, confusion, unsteadiness, clumsiness, or a combination of the symptoms thereof in a human patient; treating pain; and attenuating muscle spasticity, using pharmaceutical compositions comprising at least one alpha2-adrenergic agonist or baclofen and at least one alpha1-adrenergic agonist are disclosed.

The present invention provides a surface treatment composition and a surface treatment method capable of forming a film having excellent corrosion resistance, fingerprint resistance, blackening resistance, paint adhesion, etc. on the surface of a metal material. It contains an aqueous medium and the following components: (A) metal ions selected from Mn ions, Co ions, Zn ions, Mg ions, Ni ions, Ti ions, V ions and Zr ions, (B) having at least 4 fluorine atoms and elements selected from Ti, Zr, Si, Hf, Al and B, (C) has active hydrogen-containing amino, epoxy, vinyl, mercapto and methacryloxy Silane coupling agent with selected reactive functional groups, and (D) aqueous emulsification using resin selected from cationic or nonionic polyurethane resin, acrylic resin, epoxy resin, polyester resin and polyamide resin as the resin component Resin composition for surface treatment of metal materials and method for surface treatment of metal materials using the same.

The invention discloses a method for extracting aluminum oxide from fly ash. The method comprises the following steps of: a, acid-method treatment: mixing hydrochloric acid and fly ash, and transferring the mixture in a digester, of which the lining is made of polytetrafluoroethylene materials, for digestion, performing the separation of the pulp digested in a settling tank, evaporating and crystallizing upper-part overflow, baking the crystals to decompose the crystals into active coarse aluminum oxide and hydrogen chloride gas, wherein the hydrogen chloride gas is recovered to make acid and the acid is returned to the fly ash settling step; and b, bayer method treatment: mixing the active coarse aluminum oxide and circulating mother liquor, transferring the mixture in the digester for digestion, separating the pulp digested by settlement, performing refined filtration of the upper-part overflow to obtain refined solution, mixing the refined solution and aluminum hydroxide crystal seeds, decomposing the crystal seeds to obtain decomposed mother liquor and aluminum hydroxide, and filtering, washing and baking the aluminum hydroxide to obtain the aluminum oxide product, wherein the decomposed mother liquor is evaporated and then returned to the step of digesting the active coarse aluminum oxide. By adopting the method of the invention, the metallurgical-grade aluminum oxide meeting the requirements on national standards can be prepared.

Treatment systems are provided, which comprise a treatment element applying a treatment to a tissue, a stimulation element optically stimulating nerves in the tissue, a sensing unit sensing an electrical signal produced by nerves in the tissue in response to the optical stimulation, and a control unit controlling the application of the treatment according to the sensed signal. The systems and methods are used to avoid damaging nerves by sensing them during operation and immediately before local treatment application and preventing energy emission when the treatment tool is too close to specified nerves. Additional electric stimulation may be provided to enable avoidance of nerve damages on a larger scale, the treatment may be applied by a cold laser, and the control unit may control the treatment in realtime and in a closed loop and immediate prevent further treatment upon sensing optically stimulated nerves.

Presbyopia is treated by a method which uses various lasers to remove a portion of the scleral tissue and increase the accommodation of the presbyopic patient's eye By changing the laser power density, fluency or spot size, a single laser device having dual-function of ablation and coagulation is proposed for minimum bleeding. Fiber-bundle coupled to a single fiber is presented to increase the power density of the laser for efficient tissue ablation New mechanisms of lens curvature change and lens anterior shift are proposed for the total accommodation. The preferred laser wavelength ranges from ultraviolet to infrared including (0.15-0.36) microns, (0.9-1.6) microns, (1.8-2.2) microns and (2.8-3.2) microns Both scanning and fiber delivered systems are proposed.

The invention relates to an ultrasonic detection device and method for pipeline leakage. According to the ultrasonic detection device and method for pipeline leakage, a transmitting ultrasonic transducer and a receiving ultrasonic transducer are respectively arranged at two ends of a pipeline connector or a pipeline, the transmitting ultrasonic transducer transmits ultrasonic signals, the receiving ultrasonic transducer receives ultrasonic signals, and a preamplifier is utilized to amplify the signals; after a signal collector collects the signals, the signals are subjected to related cancellation method treatment through a computer so that defect signals are extracted, and accordingly whether the pipeline leaks is judged. The ultrasonic detection device is simple in structure and convenient to operate, detection results are accurate, detection precision is high, and real-time monitoring can be performed. Besides, according to the ultrasonic detection method, not only can leakage of the transmission pipeline be detected, but also leakage at the position of the pipeline connector can be detected, detection sensitivity and accuracy are high, antijamming capability is strong, the signal-to-noise ratio of the received signals is improved, and the defect signals can be effectively extracted simultaneously through the related cancellation treatment of the signals.

The present invention relates to a novel class of anti-cancer compounds which selectively target androgen receptor (AR)-expressing cancer cells, such as prostate cancer cells and breast cancer cells. These agents comprise an androgen receptor (AR) binding moiety, which selectively targets the compounds to (AR)-expressing cancer cells, and a cytotoxic ablating moiety, such as a nitrogen mustard moiety. The inherent high density expression of the androgen receptor in certain cancers, such as prostate cancer and breast cancer, is thus used as a tool to selectively increase the intracellular concentration of cytotoxic compounds, such as alkylating agents, e.g. DNA alkylating agents, by selectively targeting the agents to the AR-expressing cancer cells. These agents, either alone or in a composition, are thus useful for treating, delaying the progression of, treating the recurrence of, suppressing, inhibiting or reducing the incidence of cancers characterized by the presence of AR-expressing cells, such as prostate cancer. Accordingly, the present invention provides a) methods of selectively killing an (AR)-expressing cancer cell; b) methods of inducing apoptosis in an (AR)-expressing cancer cell; c) methods of treating a cancer characterized by the presence of AR-expressing cells in a subject; d) methods of delaying the progression of a cancer characterized by the presence of AR-expressing cells in a subject; e) methods of treating the recurrence of a cancer characterized by the presence of AR-expressing cells in a subject; f) methods of suppressing, inhibiting or reducing the incidence of a cancer characterized by the presence of AR-expressing cells in a subject; and g) methods of treating metastasis of a cancer characterized by the presence of AR-expressing cells in a subject; by administering to the subject or by contacting the cancer cells with a compound comprising an androgen receptor ligand moiety and an alkylating moiety, such as the novel compounds described herein.

The invention provides a household garbage incineration residue treatment method. The household garbage incineration residue treatment method comprises the following steps: (1) sorting large-sized materials; (2) carrying out magnetic separation, namely extracting magnetic metal by virtue of the magnetic separation; (3) carrying out multilevel screening on particles with particle sizes greater than 5mm so as to reserve the particles with the particle sizes smaller than 5mm; (4) carrying out eddy current separation, namely respectively extracting multiple groups of nonmagnetic metal in the particles with the particle sizes greater than 5mm by virtue of the eddy current separation; and (5) carrying out wet-method treatment, namely feeding an appropriate amount of circulating water into the particles with particle sizes smaller than 5mm, separating the particles by virtue of a jigging machine and a table concentrator, and extracting the nonmagnetic metal in the range of the particle size. By adopting the household garbage incineration residue treatment method, under the condition that the water consumption and the production amount of sewage and sludge can be reduced by more than 50 percent, the residue aggregates in different particle size ranges can be produced, the nonmagnetic metal with the particle size smaller than 5mm can be maximally extracted, the investment is less than the investment of a pure-dry-method treatment process, and the economic benefit is ideal.

Apparatus and method for the precision aiming of a radiation beam for treating an internal cancer tumor in a patient. The method of treatment includes introducing at least one reference marker into the patient in a defined and locatable position in relation to the cancer tumor. A defined point in the cross section of the beam is located by a sight that is compared to the position of the reference marker and adjusted to ensure that the treatment beam is directed precisely at the cancer tumor before the remaining doses of radiation are given to the patient. The device according to the invention includes equipment for emitting a treatment beam, a sight arranged in the path of the beam to define a point in the cross section of the beam, and a device to read the beam arranged to receive the beam that has passed through the patient and visualize the position of the at least one said reference marker and the position of the sight.

The invention belongs to the field of antimony smelting arsenic alkali residue treatment and particularly discloses a wet-method recycling and harmless treatment process for antimony smelting arsenicalkali residue. The process adopts a whole-wet-method treatment process and mainly comprises the eight working procedures of breaking, dissolving for leaching, oxidation for antimony outlet, purification for impurity removing, transition for crystallizing, reduction for arsenic sinking, evaporative crystallization and secondary residue harmless treatment. Recycling and harmless treatment of the arsenic alkali residue, zero emission of waste residue and waste water and up-to-standard discharge of exhaust gas are thoroughly achieved, the long-term plagued arsenic alkali residue environmental pollution problem in the antimony smelting industry in China is thoroughly solved, and the environmental risk caused by stacking the arsenic alkali residue is eliminated; and meanwhile, separation, enrichment and effective recovering of valuable elements are achieved.

Provide herein are fusion polypeptides that comprise a CD47 extracellular domain or a variant thereof that is fused to a Fc polypeptide. The fusion polypeptides are useful for treating an immunological disease or disorder in a subject according to the methods described herein. The fusion polypeptides are capable of suppressing immunoresponsiveness of an immune cell, inhibiting production of proinflammatory cytokines, including inhibiting immune complex-induced production of cytokines.

The invention relates to a preparation method of water-in-water type cationic polyacrylamide emulsion, which comprises the following steps of: a) adding a monomer, inorganic salt and a dispersing agent into a reactor, adding water to dissolve the mixture and controlling the mass concentration of the inorganic salt to be 30-40% to obtain a reaction liquid; b) heating the reaction liquid up to 35-50 DEG C, and filling nitrogen to remove oxygen; and c) adding an initiator into the reaction liquid, stirring for reaction for 5-12hours under the protection of nitrogen, dripping water into the reaction liquid within the period and adjusting the mass concentration of the inorganic salt to be 20-30% to obtain the emulsion product after the reaction. The method is simple. The water-in-water type cationic polyacrylamide emulsion prepared by the method has the characteristics of high molecular weight and stable storage, and is convenient and rapid to dissolve and free from secondary pollution to the environment; and the product is widely applied to various sewage treatments, especially to the dehydration treatment of the raw sludge produced by urban sewage treatment as well as the excess sludge, the mixed sludge and the digested sludge which are produced by biological method treatment.

Non-slip, non-constrictive, self-adhesive ice bag device for use with confined patients that comprises a flexible, preferably water-impermeable outer cover with an open end that is sealable with a leak-proof closure means, said cover having a layer of adhesive to temporarily attach said cover, when it is filled with the cooling medium, or one or more cooling packs containing the cooling medium, to the inside or the outside of a patient-care fabric that is arranged to be in close contact with an injured area of the patient, such that said cooling medium is then in close contact with said injured area, without slippage, and without the need for a potentially constrictive strapping and / or wrapping means.

Treatment fluids comprising an aqueous base fluid, a viscosifying agent, and a compliant dual-functional additive are provided. The present invention provides methods of using the treatment fluids in subterranean formations. One example of a suitable method includes providing a fracturing fluid comprising an aqueous base fluid, a viscosifying agent, and a compliant dual-functional additive that acts as a fluid loss control agent and a breaker and introducing the fracturing fluid into at least a portion of a subterranean formation at a rate and pressure sufficient to create or enhance at least one or more fractures in the subterranean formation.