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Gel for treating pet skin diseases and preparation method thereof

A technology for dermatology and gel, applied in the field of veterinary drug preparation, can solve problems such as poor treatment effect, and achieve the effects of less use times, enhanced curative effect, and high availability of effective drugs

Inactive Publication Date: 2020-07-03
YANGTZE UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to overcome the above-mentioned technical deficiencies, propose a gel for treating pet skin diseases and its preparation method, and solve the technical problem of poor therapeutic effect of veterinary drugs in the prior art

Method used

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  • Gel for treating pet skin diseases and preparation method thereof
  • Gel for treating pet skin diseases and preparation method thereof

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preparation example Construction

[0031] A second aspect of the present invention provides a method for preparing a gel for treating pet skin diseases, comprising the following steps:

[0032] S1: Mix carbomer, propylene glycol, ethyl paraben and distilled water accounting for 90-95% of the total weight of distilled water, stir evenly, put in a water bath at 60-80°C for 50-70 minutes, stir and dissolve continuously, take it out, and age at room temperature for 10 ~14h, a gel matrix was formed.

[0033] S2: Mix sodium hydroxide with distilled water accounting for 5-10% of the total weight of distilled water to prepare a sodium hydroxide solution.

[0034] S3: Add honeysuckle extract, white moss bark extract, cnidium extract, Phellodendron extract, Sophora flavescens extract, menthol, lincomycin, mometasone furoate, ornidazole, Thymol, terbinafine hydrochloride and lidocaine are stirred evenly, and the above-mentioned sodium hydroxide solution is added to obtain a gel for treating skin diseases of pets.

[003...

Embodiment 1

[0048] This embodiment provides a gel for treating skin diseases in pets, which consists of the following components:

[0049] Honeysuckle extract 2.00g, white moss bark extract 2.50g, cnidium fruit extract 3.00g, Phellodendron phellodendri extract 3.00g, flavescens extract 2.00g, menthol 3.50g, lincomycin 0.60g, mometasone furoate 0.12g, Ornidazole 4.50g, Thymol 0.25g, Terbinafine Hydrochloride 1.20g, Lidocaine 0.40g, Carbomer 1.00g, Propylene Glycol 12.00g, Ethylparaben 0.15g, Sodium Hydroxide 0.36 g, distilled water 63.42g. Wherein, the mass ratio of traditional Chinese medicine components, western medicine components and other components is 1:0.442:4.808.

[0050] The preparation method is as follows:

[0051] (1) Mix 1.00g of carbomer, 12.00g of propylene glycol, 0.15g of ethylparaben and 58g of distilled water, stir at a speed of 300r / min for 3 minutes, put it in a water bath at 65°C for 60 minutes, and then mix it with 300r / min Stir at a speed of min for 8 minutes to...

Embodiment 2

[0055] This embodiment provides a gel for treating skin diseases in pets, which consists of the following components:

[0056] Honeysuckle extract 1.99g, white moss bark extract 2.48g, cnidium fruit extract 2.98g, Phellodendron phellodendri extract 2.98g, Sophora flavescens extract 1.99g, menthol 3.48g, lincomycin 0.66g, mometasone furoate 0.13g, Ornidazole 4.92g, Thymol 0.27g, Terbinafine Hydrochloride 1.31g, Lidocaine 0.44g, Carbomer 0.99g, Propylene Glycol 11.92g, Ethylparaben 0.15g, Sodium Hydroxide 0.36 g, distilled water 62.97g. Wherein, the mass ratio of traditional Chinese medicine components, western medicine components and other components is 1:0.486:4.808.

[0057] The preparation method is as follows:

[0058] (1) Mix 0.99g of carbomer, 11.92g of propylene glycol, 0.15g of ethylparaben and 57g of distilled water, stir at a speed of 300r / min for 3 minutes, put it in a water bath at 65°C for 60 minutes, and then mix it with 300r / min Stir at a speed of min for 8 mi...

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Abstract

The invention discloses a gel for treating pet skin diseases and a preparation method thereof. The gel for treating pet skin diseases is prepared from the following raw materials based on weight percentages of 1-3% of flos lonicerae extract, 1-3% of dictamni cortex extract, 2-4% of fructus cnidii extract, 2-4% of cortex phellodendri extract, 1-3% of radix sophorae flavescentis extract, 3-5% of menthol, 0.4-0.8% of lincomycin, 0.1-0.2% of mometasone furoate, 3-6% of ornidazole, 0.2-0.4% of thymol crystals, 1-2% of terbinafine hydrochloride, 0.3-0.6% of lidocaine, 0.5-1.5% of carbomer, 5-20% ofpropylene glycol, 0.1-0.2% of ethylparaben, 0.3-0.5% of sodium hydroxide and 45.8-79.1% of distilling water. According to the gel for treating pet skin diseases, through the cooperation of Chinese andWestern medicines, the curative effect is enhanced, restrict is achieved between each other and the side effects are reduced; and the gel for treating pet skin diseases, such as skin itching, swelling, scales, ulceration and the like has the characteristics of wide antibacterial spectrum, high effective medicine utilization rate, less use times per day, low production cost, less medication, goodcurative effect, high safety and high economic benefit.

Description

technical field [0001] The invention relates to the technical field of veterinary drug preparation, in particular to a gel for treating skin diseases of pets and a preparation method thereof. Background technique [0002] In recent years, the number of family pets has increased significantly, and some pets have become members of the family. However, because pets often play outdoors and have thick coats, they are prone to skin diseases caused by pathogenic factors. While accompanying people, pets' skin diseases may be transmitted to family members due to close contact. Pet skin disease is a general term for pet skin itching, redness, scales, ulceration and other diseases. There are many causes of pet skin diseases. When veterinarians treat the etiology in clinical practice, due to the shortcomings of the existing clinical veterinary drugs, such as narrow antibacterial spectrum, low utilization of effective drugs, many times of daily use, large dosage, and the need for multip...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K9/06A61P17/00A61P17/04A61P17/02A61P31/02A61K31/045A61K31/7056A61K31/58A61K31/4164A61K31/05A61K31/137A61K31/167
CPCA61K9/0014A61K9/06A61K31/045A61K31/05A61K31/137A61K31/167A61K31/4164A61K31/58A61K31/7056A61K36/234A61K36/355A61K36/489A61K36/75A61K36/756A61K47/32A61K2236/33A61K2236/51A61P17/00A61P17/02A61P17/04A61P31/02A61K2300/00
Inventor 杨丰利万春云刘诗雨赵懿侔赵梦杉吕熙邱实
Owner YANGTZE UNIVERSITY