Healthy aging diagnosis marker and application

A technology for diagnosing markers and markers, applied in the field of biomedicine, to achieve the effects of high accuracy and sensitivity, high sensitivity and high accuracy
CN111380979AInactive Publication Date: 2020-07-07KUNMING INST OF ZOOLOGY CHINESE ACAD OF SCI

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
KUNMING INST OF ZOOLOGY CHINESE ACAD OF SCI
Publication Date
2020-07-07
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a healthy aging diagnosis marker and application thereof. The marker is prepared from one or more of alpha-N-phenylacetyl-L-glutamine, 4-methylphenol, N6-methyladenosine, N1-methyl-2-pyridone-5-carboxamide, 3-phenyllactic acid, 5-hydroxyindoleacetic acid, dopamine, 4-hydroxyphenylpyruvic acid, propionylglycine, 4-aminohippuric acid, indoxyl sulfate, 3,4-dihydroxybutyric acid, O-acetylserine, N2,N2-dimethyl guanosine, N-ticagrelor glycine, threitol, methoxyacetic acid, indole-3-pyruvic acid, L-histidine, homoarginine and arachidonic acid. The marker has the characteristics of high accuracy and high sensitivity, and can be directly used as an index for healthy aging.
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Description

Technical field

[0001] The invention belongs to the field of biomedical technology, and specifically relates to a diagnostic marker for healthy aging and its application. Background technique

[0002] The aging rate of my country's population is more than twice that of Western countries. Among them, the number of people over 65 will increase from 119 million in 2010 to 360 million in 2050 (accounting for 25.6% of the total population). The intensification of the aging process and the high incidence of senile diseases have seriously affected the quality of life of Chinese people. Considering that senile diseases are often difficult to cure after they occur, it is very necessary to discover the key markers of healthy aging and to evaluate the healthy aging characteristics of the aging population.

[0003] At present, the internationally recognized and known factors of healthy aging mainly focus on the discovery of longevity genes, such as the longevity genes FOXO3 and APOE. However...

Claims

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