Method for detecting dopamine by acidified graphdiyne nanotube/short multi-walled carbon nanotube modified electrode

A technology of multi-walled carbon nanotubes and acidified graphite, which is applied in the direction of measuring devices, electrochemical variables of materials, and material analysis through electromagnetic means, can solve the problems of insufficient sensitivity of DA quantification and high detection sensitivity, so as to improve electron transmission efficiency, High enrichment capacity and low cost effect

Active Publication Date: 2020-07-31
HUNAN UNIV OF SCI & TECH
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Problems solved by technology

[0006] The purpose of the present invention is aimed at the average content of DA in the human body at 10 -6 ~10 -9 In the M range, many traditional electrochemical techniques are not sensitive enough for DA quantifica

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  • Method for detecting dopamine by acidified graphdiyne nanotube/short multi-walled carbon nanotube modified electrode
  • Method for detecting dopamine by acidified graphdiyne nanotube/short multi-walled carbon nanotube modified electrode
  • Method for detecting dopamine by acidified graphdiyne nanotube/short multi-walled carbon nanotube modified electrode

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Embodiment Construction

[0027] The present invention will be further described in detail below in conjunction with specific embodiments and accompanying drawings.

[0028](1) Preparation of short multi-walled carbon nanotubes: disperse 10 mg multi-walled carbon nanotubes in 1:2 10 mL concentrated HNO 3 (68%) and H 2 SO 4 (98%) mixture, sonicated in 80°C water bath for 4 hours, then cooled with ice water and slowly diluted to prevent further reaction, then centrifuged at 15000 rpm, washed thoroughly with distilled water, repeated cycle until The pH value of the supernatant was 7, and after centrifugation, it was dried in an oven at 60°C for 24 hours;

[0029] (2) Treatment of graphyne nanotubes: Disperse 5 mg graphyne nanotubes in 5 mL concentrated HNO at a ratio of 1:2 3 (68%), and H 2 SO 4 (98%) and the mixture, treated in a 70°C water bath for 8 hours, cooled with ice water, then centrifuged at 12,000 rpm for 15 min to remove mixed acids, and then washed repeatedly with distilled water until t...

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Abstract

The invention relates to a method for detecting dopamine by an acidified graphdiyne nanotube/short multi-walled carbon nanotube modified electrode. By using composite graphdiyne nanotubes GDY and short multi-walled carbon nanotubes S-MWCNTs as electrode modification materials, a GDY/S-MWCNTs modified electrode for detecting dopamine with high sensitivity and high selectivity is prepared. As the GDY has a tremella-shaped three-dimensional surface structure, the GDY has a great effective surface area and shows ultrahigh DA enrichment capacity. The S-MWCNTs are obtained by ultrasonically treatingthe multi-walled carbon nanotubes in mixed acid, can be inserted into acupuncture points on the GDY nanotubes and are in full contact with the GDY nanosheets, so that a good way is provided for accelerating electron transmission of a sensor interface. Because the surfaces of the acidified GDY and S-MWCNT contain a large number of chemical oxygen-containing groups, some interferent molecules can be eliminated through electrostatic repulsion, so that the selectivity of a sensor interface to DA is improved. A modified electrode prepared from the material has good response performance to dopaminedetection, and the lowest detection limit can reach 8 pmol/mL.

Description

technical field [0001] The invention belongs to the field of biochemical detection, and in particular relates to a method for detecting dopamine at an acidified graphyne nanotube / short multi-wall carbon nanotube modified electrode. Background technique [0002] Graphdiyne (GDY) is a kind of sp and sp 2 Synthetic carbon allotropes with hybridized carbon atoms and π-conjugation. According to the prediction, it has many attractive properties including high fluorescence efficiency, good heat resistance, excellent electrical conductivity, etc. Since the first synthetic graphyne was reported in 2010, it has been widely used in catalysts, rechargeable batteries, solar cells, electronic devices, detectors, biomedicine, water purification and other fields. The team of Li Yuliang of the Chinese Academy of Sciences has prepared high-quality GDY nanotubes composed of entangled ultrathin GDY nanosheets. GDY is bendable and ultra-light. It has been used in lithium-ion battery negative...

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Application Information

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IPC IPC(8): G01N27/30
CPCG01N27/308
Inventor 邓克勤王毫李春香李筱芳
Owner HUNAN UNIV OF SCI & TECH
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