Hepatic extracellular space information acquisition method

A technology of information collection and liver cells, which is applied in the field of information collection in the extracellular space of liver cells, can solve the problems of inability to study the whole liver comprehensively and have many influencing factors, and achieve the effect of realizing dynamic evaluation and avoiding invasive and invasive examination
CN111487248APending Publication Date: 2020-08-04THE SECOND HOSPITAL OF SHANDONG UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
THE SECOND HOSPITAL OF SHANDONG UNIV
Publication Date
2020-08-04

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Abstract

The invention discloses a hepatic extracellular space information acquisition method, and belongs to the technical field of data information processing. The method comprises the following steps: (1),performing pretreatment; cleaning a sample, marking the sample, and standing for later use; (2), performing primary detection; to be specific, carrying out paraffin embedding and HE dyeing on the sample obtained by pretreatment in the step (1); and (3), performing final inspection; to be specific, carrying out image scanning on the sample obtained by initial inspection in the step (2), and evaluating the extracellular space of the hepatic cell. According to the method, invasive examination is avoided, fibrosis evaluation and treatment response observation can be repeatedly carried out, dynamicevaluation of pathological hepatic cells can be achieved, and the method has a positive effect on understanding of the dynamic process of liver fibrosis and fibrinolysis.
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Description

technical field

[0001] The invention belongs to the technical field of data information processing, and in particular relates to a method for collecting extrahepatic space information. Background technique

[0002] The concept of hepatic fibroproliferative disease was proposed by the famous hepatologist Hans Popper in 1984. It is now known that liver fibrosis is a group of clinicopathological syndromes. Excessive extracellular matrix hyperplasia and deposition, the pathological change is the excessive deposition of collagen, resulting in decreased microcirculation perfusion under pressure of blood vessels, further development can cause portal hypertension and fatty degeneration and necrosis of liver cells, and finally become irreversible sclerosis. Therefore, hepatic fibrosis is a common and basic link for all types of liver parenchymal damage to cirrhosis. With the in-depth study of the mechanism of liver fibrosis, some scholars have confirmed that some liver fibrosis or e...

Claims

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