A compound pharmaceutical composition for coronary heart disease

A composition and technology for coronary heart disease, applied in the direction of drug combinations, cardiovascular system diseases, active ingredients of heterocyclic compounds, etc., can solve the problem that there are no literature reports on the combined application of atorvastatin calcium and atraleuton, and no literature reports The compound pharmaceutical composition and atrileutone have little anti-inflammatory effect, so as to prevent and treat thrombosis and complications, reduce high-sensitivity C-reactive protein and plasma interleukin, and have a good protective effect
CN111494369BActive Publication Date: 2022-07-01THE FIFTH PEOPLES HOSPITAL OF SHANGHAI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
THE FIFTH PEOPLES HOSPITAL OF SHANGHAI
Publication Date
2022-07-01

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Abstract

The invention discloses the use of atorvastatin calcium and atraliuton in the preparation of medicine for treating and preventing coronary heart disease, and a compound medicine composition for treating coronary heart disease. Inhibition of high-sensitivity C-reactive protein and plasma interleukin, etc., and can stabilize the size of coronary plaque, and even have the effect of reversing plaque, and can effectively prevent and treat atherosclerotic plaque by inhibiting inflammation Thrombosis and the formation of complications in the block have a good protective effect on the cardiovascular system.
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Description

technical field

[0001] The invention belongs to the field of medicinal chemistry, in particular to the use of combined administration of atorvastatin calcium and atraruton for treating coronary heart disease and a compound pharmaceutical composition. Background technique

[0002] Coronary heart disease is coronary heart disease, which mainly refers to a series of clinical symptoms resulting from the accumulation of lipid substances in the arterial intima to form atherosclerotic lesions due to abnormal lipid metabolism. With the improvement of people's living standards, changes in living habits, and the acceleration of the aging society, the incidence of coronary heart disease is increasing, and the risk factors affecting the occurrence and development of coronary heart disease are increasing, which seriously endangers human health. At present, the common drugs for the treatment of coronary heart disease mainly include anticoagulants, vasodilators, nitrates, antiplatelet aggr...

Claims

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