Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for detecting multi-index component content of medicinal preparation

A detection method, a technology of pharmaceutical preparations, applied in the direction of measuring devices, material separation, analysis of materials, etc., to achieve the effect of good linear relationship, strong specificity, and accurate detection methods

Active Publication Date: 2020-08-21
SHANDONG BUCHANG SHENZHOU PHARMA
View PDF7 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The detection method overcomes the defects of thin layer chromatography and single component detection method in the prior art

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for detecting multi-index component content of medicinal preparation
  • Method for detecting multi-index component content of medicinal preparation
  • Method for detecting multi-index component content of medicinal preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] 1 Instruments and reagents

[0046] Waters 2695 high-performance liquid chromatography system (Waters Company); Chem Pattern 2017 pro software (Kermain (Beijing) Technology Co., Ltd.). XSE205 one hundred thousandth electronic balance (METTLER company); BK-600C ultrasonic cleaning instrument (Buck Ultrasonic Equipment Co., Ltd.).

[0047] Reference substances paeoniflorin (lot number 110736-201539, calculated by 96.4%), rosmarinic acid (lot number 111871-201706, calculated by 90.5%), baicalin (lot number 110715-201821, calculated by 95.4%), salvianolic acid B (batch number 111562-201615, calculated as 96.2%), wogonin (batch number 112002-201702, calculated as 98.5%) and paeonol (batch number 110708-201407, calculated as 99.9%) were all purchased from China National Institutes for Food and Drug Control ;

[0048] There are 13 batches of Xiaoru Sanjie Capsules, the listed drug product of the present invention (Shandong Shenzhou Buchang Pharmaceutical Co., Ltd., batch num...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a method for detecting the multi-index component content of a medicinal preparation. According to the detection method, an HPLC-DAD (High Performance Liquid Chromatography-Digital Analog Digital) method is adopted to simultaneously determine the content of six components including paeoniflorin, rosmarinic acid, baicalin, salvianolic acid B, wogonoside and paeonol in the medicinal preparation. The six components are adopted according to reference standards, and can reach the effects of comprehensively detecting the internal quality and stability of the medicine, and the medication safety and the effectiveness of the product are ensured.

Description

technical field [0001] The invention belongs to the field of detection and analysis of pharmaceutical components, and in particular relates to a method for detecting the content of multiple indicators of pharmaceutical preparations. Background technique [0002] The pharmaceutical preparation of the present invention is composed of sixteen medicines such as Bupleurum Radix, Radix Paeoniae Alba, Cyperi Cyperi, Prunella vulgaris, Angelica, Scutellaria Baicalensis, Salvia Miltiorrhiza and Moutan Cortex. The marketed drug prepared from the prescription of this pharmaceutical preparation is the core oral preparation product of gynecology (Xiaoru Sanjie Capsule) of Shandong Buchang Shenzhou Pharmaceutical Co., Ltd. In Chinese medicine, it is used clinically for diseases such as hyperplasia of mammary glands and distending pain of breast and bladder caused by stagnation of Qi due to stagnation of phlegm and stagnation of phlegm. The national drug approval number of this drug is Z2...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G01N30/02G01N30/06G01N30/14
CPCG01N30/02G01N30/06G01N30/14G01N2030/146
Inventor 胡孝文王明耿林永强许丽丽徐兴燕臧远芳林玉梅崔巧红李军
Owner SHANDONG BUCHANG SHENZHOU PHARMA
Features
  • Generate Ideas
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com