Compound probiotics, bacterial agents and their application in the preparation of bacterial agents for the prevention and treatment of Candida albicans vaginitis

Abstract

The invention provides a compound probiotic, a bacterial agent and its application in the preparation of a bacterial agent for preventing and treating Candida albicans vaginitis. The compound probiotics include Lactobacillus plantarum SD‑H9, Lactobacillus reuteri WX‑94 and Lactobacillus rhamnosus SD‑L8, all of which are preserved in the China General Microorganism Collection Management Center (CGMCC), the deposit numbers are CGMCC NO.16649, CGMCC NO.15062, CGMCC NO.16650. The composite probiotic bacteria agent, measured in parts by mass, includes the following components: 80-90 parts of composite probiotics, 6-8 parts of isomaltose and 0.5-1 part of cyclodextrin. The compound probiotics and their bacterial preparations provided by the invention can effectively reduce the inflammatory response, relieve and improve the symptoms of Candida albicans vaginitis, and have great application in preventing and treating Candida albicans vaginitis, an infectious disease of female reproductive tract. development prospects.

Description

technical field [0001] The invention belongs to the technical field of microorganisms, and in particular relates to a composite probiotic, a bacterial agent and its application in the preparation of a bacterial agent for preventing and treating Candida albicans vaginitis. Background technique [0002] Candida vaginitis (VVC) is a common fungal infection of vaginal mucosa in women of childbearing age. According to statistics, about 3 / 4 of women of childbearing age in China have suffered from the disease at least once, and Candida albicans is the main cause of the disease. Pathogenic bacteria (60%-80%). A variety of factors can affect a woman's susceptibility to C. albicans, most commonly fluctuating hormone levels and antibiotic use. More than 75% of women suffer from the disease at least once in their lifetime, and about 10% of them can be transformed into recurrent candidal vaginitis (RVVC), that is, experiencing ≥4 episodes of candidal vaginitis in a year, vaginal inflamm...

AI Technical Summary

Problems solved by technology

[0003] In the traditional treatment plan, antibiotics are the main means of clinical treatment of candidal vaginitis, but the use of antibiotics has side effects such as high recurrence rate and drug dependence

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