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Composition containing ectoin and applications of composition in laser cosmetology

A technology of ectoine and composition, applied in the field of cosmetics, can solve problems such as adverse reactions and no obvious anti-inflammatory effect, and achieve the effect of perfect protection and enhanced preventive effect

Pending Publication Date: 2020-09-29
BLOOMAGE BIOTECHNOLOGY CORP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Publication number CN105477342A invented a traditional Chinese medicine repair cream for postoperative whitening and repairing, which contains many traditional Chinese medicine extracts such as Centella asiatica and Chuanxiong, but the natural source plant extracts contain unknown side effects or adverse reactions under synergistic effects, etc.
Publication No. CN110141627A invented a formula for wound care, including aloe vera gel, propolis, etc., but its efficacy is sterilization, pain relief, no obvious anti-inflammatory effect and is also used for postoperative care

Method used

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  • Composition containing ectoin and applications of composition in laser cosmetology
  • Composition containing ectoin and applications of composition in laser cosmetology

Examples

Experimental program
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Effect test

Embodiment

[0041] The experimental methods used in the following examples are conventional methods unless otherwise specified.

[0042] The ectoine used in the following examples was purchased from sigma, the polymer sodium hyaluronate was purchased from Bloomage Biotechnology Co., Ltd., the oligomeric hyaluronate was purchased from Bloomage Biotechnology Co., Ltd., and dermatan sulfate Sodium was purchased from China National Institute for the Control of Pharmaceutical and Biological Products, and butanediol was purchased from Sinopharm Group.

experiment example 1

[0043] Experimental Example 1: Preventive and repairing effects of the composition on photodamage

[0044] The damage caused by ultraviolet laser to the skin is mainly photodamage. In this experiment, the sample was used to treat the immortalized human keratinocyte cell line before ultraviolet light, and the cell proliferation was observed, so as to determine whether the composition had a certain effect of preventing photodamage. The experiment also carried out sample treatment on the cells after light exposure to observe whether it has certain repairing and anti-inflammatory effects.

[0045] 1. Experimental materials and instruments: ectoine (sigma, ectoine), polymer sodium hyaluronate (molecular weight 10×10 5 -18×10 5 Da, Bloomage Biotechnology Co., Ltd.), oligomeric sodium hyaluronate (molecular weight3 Da, Bloomage Biotechnology Co., Ltd.), dermatan sulfate sodium (3×10 4 -6×10 4 Da, National Institute for the Control of Pharmaceutical and Biological Products), butan...

experiment example 2

[0073] The preventive and repairing effect of experimental example 2 composition on heat damage

[0074] Infrared laser damage to the skin is mainly thermal damage. In this experiment, the sample is used to treat the immortalized human keratinocyte cell line before heating, and the cell proliferation is observed, so as to determine whether the composition has a certain effect of preventing heat damage. The experiment also conducted sample processing on the heated cells to observe whether it has certain repairing and anti-inflammatory effects.

[0075] 1. Experimental materials and instruments: ectoine (sigma, ectoine), polymer sodium hyaluronate (molecular weight 10×10 5 -18×10 5 Da, Bloomage Biotechnology Co., Ltd.), oligomeric sodium hyaluronate (molecular weight3 Da, Bloomage Biotechnology Co., Ltd.), dermatan sulfate sodium (3×10 4 -6×10 4 Da, National Institute for the Control of Pharmaceutical and Biological Products), butanediol (Sinopharm Group), immortalized human...

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Abstract

The invention relates to a composition containing ectoin and applications of the composition in laser cosmetology. The composition includes 2-3 parts by weight of ectoin, 0.1-0.5 part by weight of polymer sodium hyaluronate, 0.1-0.5 part by weight of oligomeric sodium hyaluronate, 2-9 parts by weight of dermatan sulfate sodium and 3-5 parts by weight of butanediol, complementing to 100 parts by weight with water. The composition has synergistic effect, and can prevent and repair the complications in laser therapy, such as various inflammatory reactions. The obtained composition is moisturizedand non-irritant, simple in preparation method and easy to compound, has no toxic and side effects, and can be applied to pharmaceutical preparations, cosmetics, etc.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to an ectoine-containing composition and its preventive and restorative anti-inflammatory effects and its application in laser cosmetology. Background technique [0002] Nowadays, people's pursuit of beauty is constantly improving, and the technology in the field of beauty is also improving. Laser beauty is one of the most effective. Laser therapy relies on the thermal effect of high-energy light waves to selectively and effectively destroy target cells and avoid damage to surrounding normal tissues. It has been used in the fields of pigmented lesions, wrinkle removal, and photorejuvenation. Although laser cosmetology has the advantages of good curative effect, less side effects and high safety compared with previous cosmetology techniques, it still requires postoperative care and has the disadvantages of postoperative complications. [0003] Postoperative complicatio...

Claims

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Application Information

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IPC IPC(8): A61K8/34A61K8/49A61K8/73A61Q19/00A61Q19/02A61K31/505A61K31/728A61P17/00A61P29/00
CPCA61K8/4953A61K8/735A61K8/345A61K8/73A61Q19/00A61Q19/02A61K31/728A61K31/505A61P29/00A61P17/00A61K2800/592
Inventor 陈晨王冠凤石艳丽钱晓路董艳美郭学平
Owner BLOOMAGE BIOTECHNOLOGY CORP LTD
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