Supercharge Your Innovation With Domain-Expert AI Agents!

Pharmaceutical composition for treating limb spastic diseases as well as preparation method, preparation and application thereof

A composition and disease technology, applied in the field of medicine, can solve the problems of muscle atrophy, joint contracture, deformation and the like of the affected limb

Inactive Publication Date: 2020-09-29
昆明市中医医院
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

With the improvement of living standards, there are more and more people owning private cars. Due to various reasons, car accident injuries are on the rise. The number of patients with craniocerebral trauma and spinal cord injury caused by car accident injuries is increasing day by day. Increased muscle tension or spasm will occur in paralyzed limbs. If the increased muscle tension cannot be treated in a timely and effective manner, it will not only cause pain in the affected limb, but also cause muscle atrophy, joint contracture and deformation of the affected limb, resulting in limited range of motion and Rehabilitation training is difficult, which ultimately affects the recovery of mobility in stroke patients
At present, there are few western medicines for reducing muscle tension, more side effects, and higher cost. There are also few internal and external Chinese patent medicines for the increase of muscle tension or spasm in paralyzed limbs. Therefore, it is necessary to develop a product that can fundamentally solve the above problems. is very necessary

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0016] The preparation method of the pharmaceutical composition for treating spasticity of limbs according to the present invention includes pretreatment, extraction and posttreatment steps, specifically including:

[0017] A. Pretreatment: Weigh the raw materials of the formula ratio, pulverize and sieve to obtain material a for subsequent use;

[0018] B. Extraction: add an alcohol solution 3 to 8 times the weight of material a to material a and extract to obtain extract b;

[0019] C. Concentrate, dry, pulverize and sieve the extract b to obtain a pharmaceutical composition for treating spasticity of limbs.

[0020] The crushing and sieving described in step A is crushing through a 10-50 mesh sieve.

[0021] The extraction described in step B is one or more of immersion extraction, percolation extraction, and reflux extraction.

[0022] The extraction is extraction by dipping.

[0023] The temperature of the dipping extraction is 20-60° C., and the extraction time is 10-...

Embodiment 1

[0029] Weigh 100g of papaya, 50g of safflower, and 80g of Aconitum aconitum, add it into an 80% alcohol solution with a volume percentage concentration 8 times the total weight of the medicinal materials, and extract it under reflux for 48 hours at a temperature of 60°C to obtain an extract, which is concentrated, dried, and pulverized Sieve to obtain the target pharmaceutical composition.

Embodiment 2

[0031] Weigh 120g of papaya, 70g of safflower, and 100g of Aconitum aconitum, add it into a 60% alcohol solution with a volume percentage concentration 3 times the total weight of medicinal materials, extract by percolation at a temperature of 20°C for 72h to obtain an extract, concentrate, dry, Pulverize and sieve to obtain the target pharmaceutical composition.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a pharmaceutical composition for treating limb spastic diseases as well as a preparation method, preparation and application thereof. The pharmaceutical composition for treating the limb spasmodic diseases comprises the following raw material medicines in parts by weight: 100-120 parts of fructus chaenomelis, 50-70 parts of flos carthami and 80-100 parts of radix aconiti preparata. The pharmaceutical composition is prepared by the steps of pretreatment, extraction and post-treatment. The preparation method comprises the steps of pretreatment, extraction and post-treatment. The preparation is a tincture and an external lotion prepared by adding pharmaceutically acceptable auxiliary materials into the pharmaceutical composition for treating the limb spasmodic diseases. The application is the application of the pharmaceutical composition for treating the limb spastic diseases in preparation of drugs for treating the limb spastic diseases after stroke, craniocerebral trauma and spinal cord injury. The pharmaceutical composition for treating the limb spastic diseases has a relatively good curative effect for relieving paralyzed limb hypermyotonia or spasm by external use, and is low in price.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for treating spasticity of limbs, a preparation method, preparation and application thereof. Background technique [0002] Stroke is a disease with high morbidity, mortality and disability. During the development of limb paralysis, the muscle tension or spasm of the paralyzed limb will almost always appear. Spastic paralysis is one of the common sequelae of stroke patients. With the improvement of living standards, there are more and more people owning private cars. Due to various reasons, car accident injuries are on the rise. The number of patients with craniocerebral trauma and spinal cord injury caused by car accident injuries is increasing day by day. Increased muscle tension or spasm will occur in paralyzed limbs. If the increased muscle tension cannot be treated in a timely and effective manner, it will not only cause pain in the ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/732A61K36/8905A61K47/10A61P21/02
CPCA61K9/0014A61K36/236A61K36/286A61K36/704A61K36/714A61K36/732A61K36/8905A61K47/10A61K2236/333A61P21/02A61K2300/00
Inventor 刘朵顾力华陈奇刚和智娟林珑耿春梅
Owner 昆明市中医医院
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More