Pharmaceutical composition for treating limb spastic diseases as well as preparation method, preparation and application thereof
A composition and disease technology, applied in the field of medicine, can solve the problems of muscle atrophy, joint contracture, deformation and the like of the affected limb
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preparation example Construction
[0016] The preparation method of the pharmaceutical composition for treating spasticity of limbs according to the present invention includes pretreatment, extraction and posttreatment steps, specifically including:
[0017] A. Pretreatment: Weigh the raw materials of the formula ratio, pulverize and sieve to obtain material a for subsequent use;
[0018] B. Extraction: add an alcohol solution 3 to 8 times the weight of material a to material a and extract to obtain extract b;
[0019] C. Concentrate, dry, pulverize and sieve the extract b to obtain a pharmaceutical composition for treating spasticity of limbs.
[0020] The crushing and sieving described in step A is crushing through a 10-50 mesh sieve.
[0021] The extraction described in step B is one or more of immersion extraction, percolation extraction, and reflux extraction.
[0022] The extraction is extraction by dipping.
[0023] The temperature of the dipping extraction is 20-60° C., and the extraction time is 10-...
Embodiment 1
[0029] Weigh 100g of papaya, 50g of safflower, and 80g of Aconitum aconitum, add it into an 80% alcohol solution with a volume percentage concentration 8 times the total weight of the medicinal materials, and extract it under reflux for 48 hours at a temperature of 60°C to obtain an extract, which is concentrated, dried, and pulverized Sieve to obtain the target pharmaceutical composition.
Embodiment 2
[0031] Weigh 120g of papaya, 70g of safflower, and 100g of Aconitum aconitum, add it into a 60% alcohol solution with a volume percentage concentration 3 times the total weight of medicinal materials, extract by percolation at a temperature of 20°C for 72h to obtain an extract, concentrate, dry, Pulverize and sieve to obtain the target pharmaceutical composition.
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