Unlock instant, AI-driven research and patent intelligence for your innovation.

Preparation method of photo-thermal antibacterial near-infrared carbon quantum dots as well as product and application thereof

An infrared carbon and quantum dot technology, applied in the field of bioimaging and antibacterial carbon nanometers, can solve the problems of drug resistance, cytotoxicity of metal element nanomaterials, side effects of antibacterial materials, etc., achieving low cost, good low toxicity, and small side effects. Effect

Active Publication Date: 2020-11-10
NANJING NORMAL UNIVERSITY
View PDF6 Cites 11 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Purpose of the invention: Aiming at the problems existing in existing antibacterial materials, the present invention prepares a kind of photothermal antibacterial near-infrared carbon quantum dots (referred to as RCQDs). The preparation method of the near-infrared carbon quantum dots prepared by the present invention is simple and convenient and does not require expensive instruments , can make up for the gaps in this technology and the gaps in multiple fields at the same time; solve: 1. The cytotoxicity problem of nanomaterials containing metal elements; 2. The problem of drug resistance in the process of treating bacterial infections; 3. The problem of side effects

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of photo-thermal antibacterial near-infrared carbon quantum dots as well as product and application thereof
  • Preparation method of photo-thermal antibacterial near-infrared carbon quantum dots as well as product and application thereof
  • Preparation method of photo-thermal antibacterial near-infrared carbon quantum dots as well as product and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Preparation of near-infrared carbon quantum dots

[0042] Step 1: Weigh 6g of urea, 2g of citric acid, and 0.5g of copper chloride into a clean 80mL beaker, add 30mL of dimethyl sulfoxide, and stir magnetically at 800rpm for 30min at 25°C.

[0043] Step 2, transfer the solution to a polytetrafluoroethylene hydrothermal reaction kettle, place it in an oven, and heat it at a constant temperature of 160° C. for 8 hours.

[0044] Step 3, after the reaction is completed, the product to be synthesized is cooled to 25°C.

[0045] Step 4, mix the obtained brown-black solution and ethanol according to the volume ratio of 1:3, place in a centrifuge and centrifuge at a speed of 10000r / min for 15min, add 25mL deionized water to the obtained precipitate, and Sonicate for 30min to disperse.

[0046] In step 5, the obtained solution was dialyzed in a 1000 Da dialysis bag for 3 days, and the water was changed every 12 hours.

[0047] Step 6: Place the solution obtained after dialysi...

Embodiment 2

[0051] Preparation of near-infrared carbon quantum dots:

[0052] Step 1: Weigh 6g of urea, 2g of citric acid, and 0.5g of copper chloride into a clean 80mL beaker, add 30mL of dimethyl sulfoxide, and stir magnetically at 800rpm for 30min at 25°C.

[0053] Step 2, transfer the solution to a polytetrafluoroethylene hydrothermal reaction kettle, place it in an oven, and heat it at a constant temperature of 160° C. for 6 hours.

[0054] Step 3, after the reaction is completed, the product to be synthesized is cooled to 25°C.

[0055] Step 4, mix the obtained brown-black solution and ethanol according to the volume ratio of 1:3, place in a centrifuge and centrifuge at a speed of 10000r / min for 15min, add 25mL deionized water to the obtained precipitate, and Sonicate for 30min to disperse.

[0056] In step 5, the obtained solution was dialyzed in a 1000 Da dialysis bag for 3 days, and the water was changed every 12 hours.

[0057] Step 6: Place the solution obtained after dialys...

Embodiment 3

[0060] Preparation of near-infrared carbon quantum dots:

[0061] Step 1: Weigh 6g of urea, 2g of citric acid, and 0.5g of copper chloride into a clean 80mL beaker, add 30mL of dimethyl sulfoxide, and stir magnetically at 800rpm for 30min at 25°C.

[0062] Step 2, transfer the solution to a polytetrafluoroethylene hydrothermal reaction kettle, place it in an oven, and heat it at a constant temperature of 160° C. for 4 hours.

[0063] Step 3, after the reaction is completed, the product to be synthesized is cooled to 25°C.

[0064] Step 4, mix the obtained brown-black solution and ethanol according to the volume ratio of 1:3, place in a centrifuge and centrifuge at a speed of 10000r / min for 15min, add 25mL deionized water to the obtained precipitate, and Sonicate for 30min to disperse.

[0065] In step 5, the obtained solution was dialyzed in a 1000 Da dialysis bag for 3 days, and the water was changed every 12 hours.

[0066] Step 6: Place the solution obtained after dialys...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
The average particle sizeaaaaaaaaaa
Login to View More

Abstract

The invention discloses a preparation method of photo-thermal antibacterial near-infrared carbon quantum dots as well as a product and application of the photo-thermal antibacterial near-infrared carbon quantum dots. The preparation method comprises the following steps: adding urea, citric acid and copper chloride into dimethyl sulfoxide, uniformly stirring and mixing, carrying out high-temperature reaction, cooling a reaction product, mixing the reaction product with ethanol, centrifuging, and dissolving an obtained precipitate into deionized water to obtain a mixed solution; dialyzing, freezing and drying to obtain the near-infrared carbon quantum dots. Compared with other carbon quantum dots, the near-infrared carbon quantum dot obtained in the invention can realize photo-thermal sterilization and cell imaging in the biomedical field, has good biocompatibility, low toxicity and good sterilization performance, does not produce bacterial drug resistance and the like, and has good application prospects. Therefore, the method has a wide application prospect in the fields of biological imaging and antibiosis in the future.

Description

technical field [0001] The invention belongs to the technical fields of biological imaging and antibacterial carbon nanometers, and in particular relates to a preparation method of photothermal antibacterial near-infrared carbon quantum dots and its products and applications. Background technique [0002] Bacterial infection is one of the biggest global challenges facing human health. The traditional antibacterial strategy is mainly based on antibiotic treatment. However, the extensive use of antibiotics has caused the problem of drug resistance of bacterial strains, threatening human life and increasing the economic burden of treating infection. , therefore, there is an urgent need to develop new antimicrobial therapies. In recent years, with the rapid development of nanotechnology, many nanomaterials have been applied in the field of antibacterial, such as metal nanoparticles, metal sulfides / oxides have shown excellent antibacterial properties, however, the excellent antib...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C09K11/65B82Y20/00B82Y30/00A61K41/00A61P31/04G01N21/64
CPCC09K11/65B82Y30/00B82Y20/00A61K41/0057A61P31/04G01N21/6428G01N21/6458
Inventor 沈健周宁琳楚晓红王玉丽张启成孙宝宏张盼李开行孙鑫垚吕欣彤
Owner NANJING NORMAL UNIVERSITY
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com