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Micro-nano alginate fiber dressing and preparation method thereof

A kind of alginate fiber, micro-nano technology, applied in the field of medical materials, can solve the problems of chaotic internal structure, porosity and fiber shape of alginate fiber dressing, and achieve high bacterial barrier performance, low cost and high absorption The effect of liquid performance

Pending Publication Date: 2020-11-27
GUANGDONG VOCATIONAL & TECHNICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, the preparation method of the existing alginate fiber dressing is relatively simple, mainly through the cross-linking of the sodium alginate aqueous solution and the solution containing calcium ions or strontium ions to obtain water-insoluble alginate, which is broken into alginic acid after washing Salt short fiber material, formed by pressing etc.
The internal structure of the prepared alginate fiber dressing is chaotic, and the porosity and fiber shape cannot be controlled.

Method used

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  • Micro-nano alginate fiber dressing and preparation method thereof
  • Micro-nano alginate fiber dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Example 1, a micronano alginate fiber dressing. Specifically include steps:

[0024] 1) Using the hygroscopic non-woven fabric layer as the receiving base fabric for spinning, using microfluidic spinning technology, the sodium alginate solution is spun on the hygroscopic non-woven fabric layer, so that the fiber size of the micro-nano alginate fiber layer is 0.1 μm~5 μm, the pore size is 0.1 μm~5 μm, and the hygroscopic non-woven fabric layer is immersed in the solution containing calcium ions or strontium ions, so that the sodium alginate solution and the solution containing calcium ions or strontium ions are cross-linked and Cured on the moisture-absorbing non-woven fabric layer to obtain composite A;

[0025] 2) The moisture-absorbing non-woven fabric layer of composite A is laminated with the polypropylene melt-blown cloth layer, and hot-pressed and laminated by point bonding to obtain composite B;

[0026] 3) The polypropylene melt-blown cloth layer of compound B...

Embodiment 2

[0030] Embodiment 2, a kind of micronano alginate fiber dressing, such as figure 2 shown. The difference from Example 1 is that an adhesive layer 005 is also provided between the polypropylene melt-blown cloth layer 003 and the non-woven fabric surface layer 004 . The adhesive layer 005 is formed by curing medical acrylate adhesive. The micro-nano alginate fiber layer 001, the moisture-absorbing non-woven fabric layer 002, and the polypropylene melt-blown cloth layer 003 together form a composite B, and the area of ​​the non-woven fabric surface layer 004 and the adhesive layer 005 is larger than the composite B, and A margin area of ​​more than 0.5 cm is extended on the periphery of the composite B, so that the whole can become a medical product that directly covers the patient's wound and adheres to the peripheral skin of the wound.

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Abstract

The invention discloses a micro-nano alginate fiber dressing. The micro-nano alginate fiber dressing sequentially comprises a micro-nano alginate fiber layer, a moisture absorption non-woven fabric layer, a polypropylene melt-blown fabric layer and a non-woven fabric surface layer, wherein the micro-nano alginate fiber layer is formed by spinning a sodium alginate solution with the fiber size of micron to nanometer according to the gap size of micron to nanometer and crosslinking and curing the sodium alginate solution and a solution containing calcium ions or strontium ions. Because of a micro-nano structure of the micro-nano alginate fiber layer and the use of the polypropylene melt-blown fabric cloth, compared with an alginic acid dressing product on the market, the micro-nano alginatefiber dressing has high-efficiency liquid absorption performance and bacterium blocking performance (because the diameter of most bacteria is between 0.5[mu]m and 5[mu]m, the micro-nano structure of the material has the bacterium blocking performance), because the composite structure is adopted, compared with the commercially available alginic acid dressing with the same liquid absorption performance, a smaller amount of alginate material can be used, and the cost is lower.

Description

technical field [0001] The invention relates to the technical field of medical materials, in particular to a micronano alginate fiber dressing and a preparation method thereof. Background technique [0002] The main ingredient of alginate medical dressing is alginate, which is a natural polysaccharide carbohydrate extracted from seaweed, and is a kind of natural cellulose. The medical dressing can form a soft gel after being exposed to wound exudate, provide an ideal moist environment for wound healing, promote wound healing, relieve wound pain, and reduce scar formation. At the same time, it is safe, non-toxic, highly hygroscopic, hemostatic, and gel-forming. [0003] However, the preparation method of the existing alginate fiber dressing is relatively simple, mainly through the cross-linking of the sodium alginate aqueous solution and the solution containing calcium ions or strontium ions to obtain water-insoluble alginate, which is broken into alginic acid after washing ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/24A61L15/28A61L15/42D01F9/04A61F13/00A61F13/02
CPCA61L15/24A61L15/28A61L15/42D01F9/04A61F13/00063A61F13/0206A61F13/0289A61L2400/12A61F13/05C08L23/12C08L5/08
Inventor 杨璧玲吴佳林王磊梁海先李竹君
Owner GUANGDONG VOCATIONAL & TECHNICAL COLLEGE