Unlock instant, AI-driven research and patent intelligence for your innovation.

A surface disinfectant for high-level biosafety laboratories and preparation method thereof

A biosafety and disinfectant technology, applied in the biological field, can solve problems such as reducing highly pathogenic pathogenic microorganisms, accidents, leakage of biosafety, etc., achieving the effects of no toxic side effects, reducing corrosiveness, and ensuring product efficacy

Active Publication Date: 2021-11-09
WUHAN INST OF VIROLOGY CHINESE ACADEMY OF SCI +1
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It not only solves the high-efficiency killing effect on highly pathogenic pathogenic microorganisms, but also solves the problem that existing disinfectants are highly corrosive to metals, especially stainless steel materials, and reduce the integrity of high-level biosafety laboratory facilities and equipment. Biosafety accidents caused by leakage of pathogenic pathogenic microorganisms

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A surface disinfectant for high-level biosafety laboratories and preparation method thereof
  • A surface disinfectant for high-level biosafety laboratories and preparation method thereof
  • A surface disinfectant for high-level biosafety laboratories and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] S1. Dissolving and mixing of materials: Take 60g of purified water to dissolve 8g of sodium sulfate and 2g of sodium carbonate, add 5g of propylene glycol and 5g of water-soluble silicone oil and mix evenly;

[0033] S2. Formation of a stable system: Add 0.2g liquid amylase, 0.1g lipase and 0.05g liquid alkaline protease to dissolve, add 8gNP-10, use a homogenizer to homogeneously emulsify at low temperature, and age for 8 hours to digest Bubble to form a stable system composed of 5g propylene glycol uniformly wrapped multi-enzyme substances, and then wrapped by emulsified microspheres formed by 8gNP-10;

[0034] S3, the final preparation of disinfectant: Slowly mix 0.01g tartrazine, 0.5g Tween-80, 2.5g dimethyl benzyl ammonium chloride, 2.25g dimethyl ethyl benzyl ammonium chloride respectively under stirring , 0.5g of C12-C16 alkyl benzyl dimethyl ammonium chloride and 0.1g of domiphene were added to the solution, after uniform stirring and mixing, 0.027g of nano-magn...

Embodiment 2

[0036] S1. Dissolving and mixing of materials: After dissolving 6g of butanediol and 4g of sodium carbonate in 60g of purified water, add 4g of glycerol and 6g of water-soluble silicone oil and mix evenly;

[0037] S2. Formation of a stable system: Add 0.2g cellulase, 0.1g lipase and 0.05g liquid alkaline protease to dissolve, add 8gNP-10, homogeneously emulsify with a homogenizer at low temperature, and age for 8 hours to eliminate Bubble, forming a stable system composed of 4g glycerol uniformly wrapped multi-enzyme substances, and then wrapped by emulsified microspheres formed by 8gNP-10;

[0038] S3, the final preparation of disinfectant solution: Slowly mix 0.01g tartrazine, 0.5g hexanediol, 2.5g dimethyl benzyl ammonium chloride, 2.25g C8-C10 dialkyl dimethyl ammonium chloride respectively under stirring , 0.5g of C12-C16 alkyl benzyl dimethyl ammonium chloride and 0.1g of domiphene were added to the solution, after uniform stirring and mixing, 0.015g of nano-magnesium w...

Embodiment 3

[0040] S1. Dissolving and mixing of materials: Take 60g of purified water to dissolve 8g of polyethylene glycol and 2g of sodium carbonate, add 5g of butanediol and 5g of water-soluble silicone oil and mix evenly;

[0041] S2. Formation of a stable system: add 0.2g liquid amylase, 0.1g cellulase and 0.05g liquid alkaline protease to dissolve, add 8gNP-10, homogenize and emulsify with a homogenizer at low temperature, and age for 8 hours Defoaming, forming a stable system composed of 5g butanediol uniformly wrapped with multi-enzyme substances, and then wrapped by emulsified microspheres formed by 8gNP-10;

[0042] S3. The final preparation of disinfectant solution: Slowly mix 0.01g tartrazine, 0.5g tetrasodium edetate, 2.5g dimethylbenzyl ammonium chloride, 2.25g dimethylethylbenzyl Add ammonium chloride, 0.5g C12-C16 alkyl benzyl dimethyl ammonium chloride and 0.1g domiphene to the solution, stir and mix evenly, add 0.035g nano-magnesium, make up the amount of water to determ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a surface disinfectant for high-level biological safety laboratories and a preparation method thereof, which comprises quaternary ammonium chloride, multi-enzyme solution, water-soluble silicone oil, emulsifier, preservative, nano-magnesium, chelating The combination of stabilizer and colorant, the invention relates to the field of biotechnology. The surface disinfectant not only has a killing effect on highly pathogenic pathogenic microorganisms such as Ebola virus, SARS coronavirus, new coronavirus and HIV, but also can significantly reduce the The corrosion effect on metals, especially stainless steel, so as to avoid the leakage of highly pathogenic pathogenic microorganisms after the metal components of high-level biosafety laboratory biosafety protection facilities are corroded and cause biosafety accidents. Magnesium is magnetized to make nano-magnesium magnetic and reduce its aggregation. Finally, nano-magnesium forms a stable dispersion system in the disinfectant, which significantly increases the stability of the disinfectant during storage and maintains the anti-metal corrosion effect of the disinfectant.

Description

technical field [0001] The invention relates to the field of biotechnology, in particular to a surface disinfectant for high-level biosafety laboratories and a preparation method thereof. Background technique [0002] There are various microorganisms in nature, some of which can cause diseases in humans or animals. These microorganisms are called pathogenic microorganisms. According to the different infectivity and pathogenicity of pathogenic microorganisms to humans and animals, they are divided into different categories. Among them Pathogenic microorganisms that can cause serious diseases in humans or animals are called highly pathogenic pathogenic microorganisms, such as Ebola virus, SARS coronavirus, new coronavirus and HIV. In order to study these highly pathogenic pathogenic microorganisms, a corresponding high-level biosafety laboratory is required, that is, a high-level biosafety laboratory. [0003] In the process of studying highly pathogenic pathogenic microorgan...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A01N33/12A01N63/50A01N25/04A01P3/00A01P1/00
CPCA01N25/04A01N33/12A01N63/50
Inventor 吴佳袁志明唐浩刘军秦颢刘毅王林
Owner WUHAN INST OF VIROLOGY CHINESE ACADEMY OF SCI