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A composition for treating pharyngitis and its preparation method

A composition and technology for pharyngitis, applied in the direction of drug combination, active ingredients of hydroxyl compounds, medical preparations of non-active ingredients, etc., can solve the problems of short residence time of drugs in the throat, limited therapeutic effect of pharyngitis, prolonged healing time of pharyngitis, etc. , achieve the effect of overcoming the side effects of drugs, improving throat dryness and congestion, and shortening the treatment time

Active Publication Date: 2022-03-29
BLOOMAGE BIOTECHNOLOGY CORP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The above-mentioned spray preparations need to spray the medicine on the throat for treatment. However, due to the particularity of the throat, frequent swallowing and breathing are required, and the amount of medicine sprayed is limited, which often causes the medicine to stay in the throat for a short time. Disadvantage of needing repeated dosing
Although chitosan and other ingredients are added in the above-mentioned patents to increase the retention time of the drug in the throat, it only contains Chinese medicine ingredients, which has limited therapeutic effect on pharyngitis and prolongs the healing time of pharyngitis.

Method used

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  • A composition for treating pharyngitis and its preparation method
  • A composition for treating pharyngitis and its preparation method
  • A composition for treating pharyngitis and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] A spray for treating pharyngitis, which includes the following components in mass percentage: 0.15% of large molecular weight sodium hyaluronate (molecular weight 70WDa), 0.15% of small molecular weight sodium hyaluronate (molecular weight of 9500Da), 1.5% of ectoine, 0.2% γ-aminobutyric acid, 2.5% bellflower extract, 0.6% verbena extract, 1.2% forsythia extract, 0.2% menthol, and the balance is purified water.

[0041] The preparation method is as follows:

[0042] Step 1: Weigh high-molecular-weight sodium hyaluronate and low-molecular-weight sodium hyaluronate, dissolve them in an appropriate amount of purified water, and obtain solution A;

[0043] Step 2: adding ectoine, γ-aminobutyric acid, bellflower extract, verbena extract, and forsythia extract into solution A under stirring, and stirring evenly to obtain solution B;

[0044] Step 3: Add menthol to Tween-80 at a ratio of 1:1 (w:w), and mix well to obtain solution C;

[0045] Step 4: Add solution C to solutio...

Embodiment 2

[0050] Prepare the spray according to the formula and method of Example 1, the difference is: 0.18% of large molecular weight sodium hyaluronate (molecular weight 80WDa), 1.8% of small molecular weight sodium hyaluronate (molecular weight 5000Da), 0.3% of ectoine, γ - 0.8% aminobutyric acid, 1.6% bellflower extract, 0.7% verbena extract, 0.82% forsythia extract, 0.3% menthol, and the balance is purified water. The preparation method is the same as in Example 1.

Embodiment 3

[0052] Prepare the spray according to the formula and method of Example 1, the difference is: 0.2% of large molecular weight sodium hyaluronate (molecular weight 110WDa), 1.0% of small molecular weight sodium hyaluronate (molecular weight of 2500Da), 1.0% of ectoine, γ - 0.6% GABA, 1.8% bellflower extract, 1.2% verbena extract, 0.6% forsythia extract, 0.1% menthol, and the balance is purified water. The preparation method is the same as in Example 1.

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Abstract

The invention discloses a composition for treating pharyngitis and a preparation method thereof, comprising 0.3%~2.0% of hyaluronic acid substances, 0.3%~1.5% of ectoine substances, and 0.2%~ 0.8%. The composition of the present invention overcomes the shortcomings of the commonly used clinical medicines for treating pharyngitis, which have large side effects, cannot be taken for a long time, and cannot effectively cure pharyngitis, effectively protects and repairs damaged throat mucosa, blocks external irritating substances, and reduces the need for medication. The number of times of medicine can be used for a long time without side effects.

Description

technical field [0001] The invention relates to a composition for treating pharyngitis and a preparation method thereof, belonging to the technical field of medicines. Background technique [0002] Pharyngitis is a general term for pharyngeal mucosal, submucosal and lymphoid tissue inflammation caused by bacterial infection, viral infection, environment and other factors. The cause of disease of pharyngitis comprises the following aspects: unreasonable cooking and diet are the most important factors causing chronic pharyngitis, including nutritional deficiency type, overnutrition and overstimulation type; surrounding adjacent organ infection factors, Chronic pharyngitis caused by diseases of adjacent organs of the pharynx is not uncommon in clinical practice, such as acute and chronic rhinitis, sinusitis, nasal polyps, deviated nasal septum, allergic rhinitis, adenoid hypertrophy, acute and chronic tonsillitis, etc. can cause chronic pharyngitis, some scholars It is believe...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/728A61K31/505A61K36/85A61K9/12A61K47/18A61P11/04A61K31/045
CPCA61K31/728A61K31/505A61K36/346A61K36/85A61K36/634A61K31/045A61K9/12A61K47/183A61K9/0073A61P11/04A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 庞萌萌李超李敏刘建建郭学平
Owner BLOOMAGE BIOTECHNOLOGY CORP LTD