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Preparation for resisting helicobacter pylori infection and preparation method of preparation

An anti-Helicobacter pylori and preparation technology, applied in the field of allicin preparations, can solve problems such as difficulty in preventing and controlling Helicobacter pylori infectious diseases, and achieve the effects of remarkable bactericidal effect and unique antibacterial mechanism.

Inactive Publication Date: 2021-03-26
GUANGZHOU HONGKANG PHARM TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the biggest problem encountered in the clinical treatment of chronic gastritis and gastric ulcer is the drug resistance of Helicobacter pylori. Despite the efforts of various disciplines, there is still no ideal way to solve this problem. very difficult

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0020] A kind of preparation method of the anti-helicobacter pylori infection preparation, comprises the following steps:

[0021] S1. Put an appropriate amount of Cortex Phellodendri in an extraction container, use ethanol as a solvent, soak Cortex Phellodendri for 2-3 hours, decoct for 2 hours, then filter to obtain filtrate, collect the filtrate, collect all the filter residue, and put it back in the extraction container , repeat the above steps 2-3 times, and finally concentrate the combined filtrate under reduced pressure and freeze-dry to obtain Phellodendron Phellodendri extract, and then weigh the Phellodendron Phellodendri extract according to the formula ratio.

[0022] S2. Take the deionized water of the formula ratio, and then add the emulsifier, surfactant, suspending agent and Phellodendron Phellodendri extract in the formula ratio into the deionized water and stir;

[0023] S3, then concentrate the mixed solution obtained in step S2 to a relative density of 1-1....

Embodiment 1

[0025] Embodiment 1, a kind of anti-helicobacter pylori infection preparation, each component counts according to its mass percentage: allicin: 40%, berberine hydrochloride: 35%, phellodendron cortex extract: 10%, emulsifier: 1% , Surfactant: 2%, suspending agent: 3%, deionized water: 9%.

[0026] Material Allicin Berberine Hydrochloride Phellodendron Extract Glyceryl monostearate sodium lauryl sulfate gum arabic Deionized water percentage 40% 35% 10% 1% 2% 3% 9%

[0027] A kind of preparation method of the anti-helicobacter pylori infection preparation, comprises the following steps:

[0028] S1. Put an appropriate amount of Cortex Phellodendri in an extraction container, use ethanol as a solvent, soak Cortex Phellodendri for 2 hours, decoct for 2 hours, then filter to obtain filtrate, collect the filtrate, and collect all the filter residues, put them in the extraction container again, The above steps were repeated twice, and finally t...

Embodiment 2

[0032] Embodiment 2, a kind of anti-helicobacter pylori infection preparation, each component counts according to its mass percentage: allicin: 35%, berberine hydrochloride: 30%, phellodendron cortex extract: 20%, emulsifier: 2% , Surfactant: 2%, suspending agent: 2%, deionized water: 9%.

[0033] Material Allicin Berberine Hydrochloride Phellodendron Extract Glyceryl monostearate sodium lauryl sulfate gum arabic Deionized water percentage 35% 30% 20% 2% 2% 2% 9%

[0034] A kind of preparation method of the anti-helicobacter pylori infection preparation, comprises the following steps:

[0035] S1. Put an appropriate amount of Cortex Phellodendri in an extraction container, use ethanol as a solvent, soak Cortex Cortex Phellodendri for 3 hours, decoct for 2 hours, then filter to obtain filtrate, collect filtrate, and collect all filter residues, put them in the extraction container again, The above steps were repeated three times, and fina...

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Abstract

The invention discloses a preparation for resisting helicobacter pylori infection and a preparation method of the preparation. The preparation comprises the following components in percentage by mass:1%-40% of allicin, 1%-40% of berberine hydrochloride, 1%-25% of a cortex phellodendri extract, 1%-2% of an emulsifier, 1%-5% of surfactant, 1%-4% of suspending aid and the balance of deionized water.The preparation has the beneficial effects that the allicin preparation is obtained by mixing allicin, berberine hydrochloride and various traditional Chinese medicines, the recurrence rate of chronic gastritis can be reduced while the eradication rate is ensured by a sterilization and anti-inflammatory method, and meanwhile, the preparation is unique in antibacterial mechanism and remarkable inhelicobacter pylori sterilization effect.

Description

technical field [0001] The invention relates to the technical field of allicin preparations, in particular to a preparation for resisting Helicobacter pylori infection and a preparation method thereof. Background technique [0002] In existing life, Helicobacter pylori disease is a spiral-shaped, micro-anaerobic, and very demanding on growth conditions. It was successfully isolated from the gastric mucosal biopsy tissue of a patient with chronic active gastritis in 1983. The only microbial species that can survive in the human stomach, Helicobacter pylori disease includes gastritis, peptic ulcer, lymphoproliferative gastric lymphoma, etc. caused by Helicobacter pylori infection. [0003] At present, the biggest problem encountered in the clinical treatment of chronic gastritis and gastric ulcer is the drug resistance of Helicobacter pylori. Despite the efforts of various disciplines, there is still no ideal way to solve this problem. Very difficult. Contents of the invent...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61P31/04A61P1/04A61K31/255A61K31/4375
CPCA61K31/255A61K31/4375A61K36/756A61P31/04A61P1/04A61K2236/33A61K2236/39A61K2300/00
Inventor 肖军宏
Owner GUANGZHOU HONGKANG PHARM TECH CO LTD