Deer blood buccal tablet and preparation method thereof

A buccal tablet, deer blood technology, applied in the biological field, can solve the problems of easy sticking in the oral cavity, fishy smell, unfavorable taking, etc.

Active Publication Date: 2021-04-30
苏州红冠庄国药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Deer blood powder is obtained by drying the blood of sika deer or red deer. When taken, it will have a fishy smell and make it difficult to swallow. In addition, because it is in powder form, it will absorb moisture after being ingested and easily stick to the mouth, so that it is difficult to swallow after taking it. Nausea or even vomiting will occur during the process, which is not conducive to taking

Method used

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  • Deer blood buccal tablet and preparation method thereof
  • Deer blood buccal tablet and preparation method thereof
  • Deer blood buccal tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0075] Formula: 25% deer blood powder, 2% colloidal silicon dioxide, 49% sorbitol, 20% mannitol, 2.5% croscarmellose sodium, 1.5% magnesium stearate.

[0076] Preparation method: after sieving and homogenizing fresh deer blood, add SteviAroma mellow and sweet essence (Ibixi (Beijing) Plant Medicine Technology Co., Ltd.), which accounts for 1 / 10,000 of the weight of deer blood, freeze-dry, grind and pulverize through 80 mesh . The specific freeze-drying process is as follows:

[0077] The freeze-drying process includes the pre-freezing stage, the first sublimation stage, the second sublimation stage, the third sublimation stage, the first analytical drying stage and the second analytical drying stage; the pre-freezing stage pre-freezes the material at a temperature of -25°C, The holding time is not less than three hours; the first sublimation stage raises the temperature from -25°C to -10°C at a uniform speed within one hour, and keeps at -10°C for not less than twelve hours; ...

Embodiment 2

[0080] Formula: 20% deer blood powder, 3% colloidal silicon dioxide, 54% sorbitol, 25% mannitol, 1.5% croscarmellose sodium, 2.5% magnesium stearate.

[0081] Preparation method: after sieving and homogenizing fresh deer blood, add SteviAroma mellow and sweet essence (Ibixi (Beijing) Plant Medicine Technology Co., Ltd.), which accounts for 1 / 10,000 of the weight of deer blood, freeze-dry, grind and pulverize through 80 mesh . The specific freeze-drying process is as follows:

[0082] The freeze-drying process includes the pre-freezing stage, the first sublimation stage, the second sublimation stage, the third sublimation stage, the first analytical drying stage and the second analytical drying stage; the pre-freezing stage pre-freezes the material at a temperature of -25°C, The holding time is not less than three hours; the first sublimation stage raises the temperature from -25°C to -10°C at a uniform speed within one hour, and keeps at -10°C for not less than twelve hours; ...

Embodiment 3

[0085] Formula: 30% deer blood powder, 1% colloidal silicon dioxide, 44% sorbitol, 15% mannitol, 3.5% croscarmellose sodium, 0.5% magnesium stearate.

[0086] Preparation method: after sieving and homogenizing fresh deer blood, add SteviAroma mellow and sweet essence (Ibixi (Beijing) Plant Medicine Technology Co., Ltd.), which accounts for 1 / 10,000 of the weight of deer blood, freeze-dry, grind and pulverize through 80 mesh . The specific freeze-drying process is as follows:

[0087] The freeze-drying process includes the pre-freezing stage, the first sublimation stage, the second sublimation stage, the third sublimation stage, the first analytical drying stage and the second analytical drying stage; the pre-freezing stage pre-freezes the material at a temperature of -25°C, The holding time is not less than three hours; the first sublimation stage raises the temperature from -25°C to -10°C at a uniform speed within one hour, and keeps at -10°C for not less than twelve hours; ...

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Abstract

The invention discloses a deer blood buccal tablet and a preparation method thereof. The buccal tablet is prepared by mixing and tabletting deer blood powder, colloidal silicon dioxide, sorbitol, mannitol, croscarmellose sodium and magnesium stearate. The buccal tablet can remove fishy smell in deer blood, is convenient for patients to take, and is also convenient to package and carry.

Description

technical field [0001] The invention belongs to the field of biotechnology, and in particular relates to a deer blood buccal tablet and a preparation method thereof. Background technique [0002] Deer blood is the blood of sika deer and red deer, which are animals of the deer family. It is a precious traditional Chinese medicine. The water content in deer blood is 80% to 81%, and organic matter accounts for 16% to 17%, mainly protein, which is rich in 19 kinds of amino acids and various enzymes, and also contains a variety of lipids, free fatty acids, phosphorus Esters, hormones, vitamins and polysaccharides, etc. Deer blood also contains γ-globulin, cystine, lysine, creatine phosphokinase related to heart function, etc. Li Shizhen of the Ming Dynasty recorded in "Compendium of Materia Medica" that "it can greatly tonify deficiency and damage, benefit essence and blood, relieve acne poison, drug poison, etc.". [0003] Deer blood powder is obtained by drying the blood of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/14A61K9/20A61K47/38A61K47/26A61K47/04A61K47/12A61P1/14A61P7/06A61P39/02
CPCA61K35/14A61K9/0056A61K9/2054A61K9/2018A61K9/2095A61K9/2009A61K9/2013A61P1/14A61P7/06A61P39/02Y02A50/30
Inventor 濮存海袁文婷
Owner 苏州红冠庄国药股份有限公司
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