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Method for separating synephrine from hesperidin waste liquid

A technology for hesperidin and hesperidin mother, applied in the field of separation of synephrine, can solve the problems of high COD content, difficult sewage treatment, complex composition of mother liquor, etc., so as to improve the recovery rate, solve the problem of sewage treatment, and the operation method can be improved. control effect

Active Publication Date: 2021-05-25
LIANYUAN KANGLU BIOLOGICAL TECH CO LTD +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The present invention provides a method for separating synephrine from hesperidin waste liquid, to solve the complex components of the mother liquor after extracting hesperidin and high COD content , sewage treatment is difficult, and the synephrine rich in hesperidin mother liquor has not been effectively developed and utilized, resulting in a technical problem of waste of resources

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  • Method for separating synephrine from hesperidin waste liquid
  • Method for separating synephrine from hesperidin waste liquid

Examples

Experimental program
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Effect test

Embodiment 1

[0050] The method for separating synephrine from hesperidin waste liquid, comprises the following steps:

[0051] S1. Put 300kg of pretreated C100E strong acid cationic resin into the stainless steel cylinder, put 10t of hesperidin mother liquor on the C100E strong acid cationic resin, and the speed of loading the hesperidin mother liquor is 7BV / h. After the sample is finished, it is eluted with water. The volume of water elution is 3.3BV, and the speed of water elution is 2BV / h. After the water elution, it is eluted with a strong alkali mixture. %NaOH and mass fraction are 0.3%KOH mixed solution, the volume of strong alkali mixed solution is 3.3BV, the flow rate of strong alkali mixed solution is 2BV / h, collect the eluate after strong alkali mixed solution elution, adopt the concentration of 10% hydrochloric acid adjusts the pH value of the eluent to 7 to obtain a neutralizing solution;

[0052] S2. Ultrafilter the neutralization solution with a 100nm ceramic membrane, then ...

Embodiment 2

[0055] S1. Put 300kg of pretreated C100E strong acid cationic resin into the stainless steel cylinder, put 15t of hesperidin mother liquor on the C100E strong acid cationic resin, and the speed of loading the hesperidin mother liquor is 10BV / h. After the sample is finished, it is eluted with water. The volume of water elution is 3.34BV, and the speed of water elution is 3BV / h. After the water elution, it is eluted with a strong alkali mixed solution. %NaOH and mass fraction of 0.1% Ca(OH) 2 The mixed solution, the volume of the strong base mixed solution is 3.34BV, the flow rate of the strong base mixed solution is 3BV / h, the eluate after the strong base mixed solution is collected, and the concentration is 20% hydrochloric acid to adjust the pH of the eluent The value is 6.5, and the neutralizing solution is obtained;

[0056] S2. Ultrafilter the neutralization solution with a 50nm ceramic membrane, then concentrate it through a 50Da nanofiltration membrane, stir the concent...

Embodiment 3

[0059] S1. Put 300kg of pretreated C100E strong acid cationic resin into the stainless steel cylinder, put 15t of hesperidin mother liquor on the C100E strong acid cationic resin, and the speed of loading the hesperidin mother liquor is 10BV / h. After the sample is finished, it is eluted with water. The volume of water elution is 3.5BV, and the speed of water elution is 3BV / h. After the water elution, it is eluted with a strong alkali mixture. %Ca(OH) 2 And the mixed solution of the mixed solution whose mass fraction is 0.1% KOH, the volume of the strong alkali mixed solution is 3.5BV, the flow rate of the strong alkali mixed solution is 3BV / h, collect the eluate after the strong alkali mixed solution is eluted, and adopt the concentration Adjust the pH value of the eluent to 7 with 20% hydrochloric acid to obtain a neutralizing solution;

[0060] S2. Ultrafilter the neutralization solution with a 500nm ceramic membrane, then concentrate it through a 500Da nanofiltration membr...

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Abstract

The invention discloses a method for separating synephrine from hesperidin waste liquid, which comprises the following steps: S1, loading a hesperidin mother liquid to strongly acidic cationic resin, after loading is finished, eluting with water, after water elution is finished, eluting with a strong alkali mixed liquid, collecting an eluate after elution with the strong alkali mixed liquid, and adjusting the pH value of the eluent to 5-7 to obtain a neutralized solution; and S2, carrying out ultrafiltration on the neutralized solution, then carrying out concentration through a nanofiltration membrane, and carrying out cooling crystallization, filtration and drying on the concentrated solution to obtain synephrine. According to the method for separating synephrine from the hesperidin waste liquid, the hesperidin waste liquid is reused, novel poncirin is extracted from the hesperidin waste liquid, the problem of sewage treatment is solved while economic benefits are obtained, and waste recycling is achieved. According to the method, ion exchange is carried out through the strongly acidic cationic resin, elution is carried out through the low-concentration strong alkali mixed solution, no strong pungent smell exists, the requirements for production equipment and the environment are low, and the requirement for green production is met.

Description

technical field [0001] The invention relates to the field of synephrine, in particular to a method for separating synephrine from hesperidin waste liquid. Background technique [0002] More than 1 billion adults are overweight (BMI) by about 25kg / m 2 ~29.9kg / m 2 ), at least 3 million people are obese (BMIP 30kg / m 2 ), directly lead to the increase of the morbidity and mortality of diseases such as diabetes, cardiovascular disease, hypertension, and cancer. Therefore, the treatment of obesity and hyperlipidemia has attracted the attention of the global medical community, and finding high-efficiency and low-toxic lipid-lowering drugs, especially natural active ingredients, has become one of the research hotspots. [0003] Synephrine, also known as p-hydroxyephrine, sympathol, and phenylephrine, exists in citrus plants of the Rutaceae family, and the young fruit of sour orange (Citrus anrantium L.) has the highest content. Synephrine has the effects of constricting blood ve...

Claims

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Application Information

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IPC IPC(8): C07C213/10C07C215/60
CPCC07C213/10C07C215/60
Inventor 肖业成魏有何刘冬敏廖深刻吴爱燕
Owner LIANYUAN KANGLU BIOLOGICAL TECH CO LTD
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