Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Electrochemiluminescence active particle, and preparation method and application thereof

An active particle and electrochemical technology, applied in the field of electrochemiluminescence, can solve the problems of low solubility, no report of aqueous ECL, etc., and achieve the effect of improving detection accuracy and eliminating background fluorescence interference

Pending Publication Date: 2021-05-28
GUANGZHOU UNIVERSITY
View PDF1 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, TADF luminescent materials essentially belong to the charge transfer state (CT) luminescence. Due to the high polarity of the water solvent in the aqueous phase ECL test environment and the destructive effects of its own high concentration of dissolved oxygen on the TADF material and its own low solubility, At present, there is no report to realize the aqueous phase ECL of TADF system

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Electrochemiluminescence active particle, and preparation method and application thereof
  • Electrochemiluminescence active particle, and preparation method and application thereof
  • Electrochemiluminescence active particle, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] This embodiment provides an electrochemiluminescent active particle and a preparation method thereof. The electrochemiluminescence active particle comprises an inner core and a polymer shell covering the inner core, the inner core is a thermally activated delayed fluorescent material, and the polymer material of the polymer shell is an amphiphilic polymer.

[0068] In this example, 2,4,5,6-tetrakis(9-carbazolyl)-isophthalonitrile (2,4,5,6-tetrakis(carbazol-9-yl) -1,3-dicyanobenzene, referred to as 4CzIPN), which does not contain metal elements, is cheap and easy to obtain, has low toxicity and good chemical stability. The synthesis method of this small molecular compound has been reported in the literature (Nature, 2012, 492, 234–238). The chemical structural formula is as follows:

[0069]

[0070] In this embodiment, distearoylphosphatidylethanolamine-polyethylene glycol 2000 (DSPE-PEG2000 for short) is selected as the amphiphilic polymer, and its chemical struct...

Embodiment 2

[0085] This embodiment provides an electrochemiluminescence detection solution of an "oxidation-reduction" type co-reactant aqueous phase electrochemiluminescence system, which differs from the electrochemiluminescence detection solution in Example 1 in that it also includes a co-reactant, Specifically, it is tripropylamine (TPrA) with a final concentration of 30 mmol / L.

[0086] Performance Testing

[0087] The detection solutions of the blank group and the control group were set respectively, wherein the blank group was 0.1mol / L PBS buffer solution containing 30mmol / L TPrA, and 4CzIPN with a final concentration of 0.025mg / mL was added in the detection solution of the control group blank group.

[0088] Using a three-electrode system (with a glassy carbon electrode as a working electrode, an Ag / AgCl electrode as a reference electrode, and a platinum wire electrode as a counter electrode) was used to detect the electrochemiluminescence analyzer in this embodiment under a nitro...

Embodiment 3

[0091] This embodiment provides an electrochemiluminescent active particle and a preparation method thereof. The electrochemiluminescence active particle comprises an inner core and a polymer shell covering the inner core, the inner core is a thermally activated delayed fluorescent material, and the polymer material of the polymer shell is an amphiphilic polymer.

[0092] In this example, poly-3,6-carbazole-9,9-dihexyl-10-(4-(4,6-di-tert-butyl-1,3,5-tri Oxyzin-2-yl)phenyl)-9,10-dihydroacridine (poly-3,6-carbazole-9,9-dihexal-10-(4-(4,6-di-tert-butyl-1 ,3,5-triazin-2-yl)phenyl)-9,10-dihydroacridine, referred to as PCzAPT), wherein the APT unit (9,9-dihexal-10-(4-(4,6-di-tert-butyl- 1,3,5-triazin-2-yl)phenyl)-9,10-dihydroacridine) has a molar ratio of 10, so it is referred to as PCzAPT10. The synthesis of this material has been reported in literature and patents (Adv.Opt.Mater.2018, 6, 1701320; ZL201710115395.3.), and can be synthesized and prepared by referring to the corresp...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an electrochemiluminescence active particle, and a preparation method and application thereof. The electrochemiluminescence active particle comprises an inner core and a polymer shell coating the inner core, and the inner core comprises a thermally-activated delayed fluorescent material. According to the electrochemiluminescence active particle provided by the embodiment of the invention, the polymer shell layer is added on the outer side of the thermally-activated delayed fluorescent material, and when the electrochemiluminescence active particle is used as a luminescent material in a water-phase electrochemiluminescence system, on the basis of the environment barrier effect of the polymer shell layer, on one hand, the influence of the polar effect of water in the water environment on the thermally-activated delayed fluorescent material is removed, and on the other hand, the direct contact between dissolved oxygen in the water environment and the thermally-activated delayed fluorescent material is blocked, so that the influence of oxygen quenching is fully inhibited. Therefore, all singlet-state and triplet-state excitons generated under the environment electrical excitation condition of a water-phase system can be completely utilized to realize efficient electrochemical luminescence.

Description

technical field [0001] The present application relates to the technical field of electrochemiluminescence, in particular to electrochemiluminescence active particles and their preparation method and application. Background technique [0002] Electrochemiluminescence (Electrochemiluminescence or Electrogenerated chemiluminescence, referred to as ECL) is a process in which an active material is electrically excited to cause a high-energy electron transfer reaction on the electrode surface, thereby generating an excited state and radiating light when it transitions back to the ground state. According to different specific processes, it can be further divided into annihilation ECL and co-reactant ECL. Annihilation-type ECL applies an alternating potential to the working electrode, causing the electrochemically active material to undergo self-oxidation and reduction reactions on the electrode surface, rapidly generating corresponding cation radicals and anion radicals, and the tw...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C09K11/06C09K11/02C08J3/12G01N21/76G01N21/64C08L65/00C08L71/02
CPCC09K11/06C09K11/025C08J3/126G01N21/76G01N21/64C08J2365/00C08J2471/02C09K2211/1029C09K2211/1007C09K2211/1458C09K2211/1433C09K2211/1416C09K2211/1425C09K2211/1466
Inventor 牛利张保华曾梓晖罗野林张玉微陈丽娟
Owner GUANGZHOU UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com