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Blood sugar reducing composition containing lithocarpus litseifolius and preparation method and application method thereof

A composition and blood sugar-lowering technology, applied in the field of blood-sugar-lowering composition containing Mujiang Yeke and its preparation, can solve the problems of single drug action mechanism, aggravation of cardiovascular complications, difficulty in ensuring drug efficacy and drug quality, and achieve The effect of reducing the source of blood sugar and increasing the outlet of blood sugar

Pending Publication Date: 2021-06-04
良甜生物医药科技江苏有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although some chemical drugs can lower blood sugar, they have different side effects or liver and kidney toxicity, and can easily lead to aggravation of cardiovascular complications
For example, DPP-IV inhibitor drugs, because of their inhibitory effect on a large class of enzymes in the body, will change the distribution of body fat, and the actual effect of administration is relatively poor
Although various Chinese patent medicines for treating diabetes have a certain therapeutic effect, it is difficult to guarantee the curative effect and quality of medicines due to the single mechanism of action of the medicine or the unclear mechanism of action and active ingredients.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Example 1: A blood sugar-lowering composition containing Ketchiba japonica, calculated according to parts by weight, comprising the following components: 15 parts of dry extract of young leaves of Keji japonica, 25 parts of dry powder of old leaf extract of phyllocarpus, mulberry leaf extract 10 parts of dry powder, 5 parts of Caulis Spatholobus extract dry powder, 10 parts of mulberry buds, 15 parts of kudzu root extract dry powder and 35 parts of auxiliary materials.

[0035] Among them, the leaf age of the young leaves of Mujiang Yeke is 1 to 2 weeks, and the leaf age of the old leaves of Mu Jiang Ye Ke is more than 8 months. According to the mass calculation, the content of trilobatin in the dry powder of the young leaves of Mu Jiang Ye Ke is 1 to 5%. The content of phlorizin in the dry powder of the leaf extract is 2-8%, the content of 1-deoxynojirimycin in the dry powder of the mulberry leaf extract is 0.1-1%, the content of the total flavonoids in the dry powder o...

Embodiment 2

[0038] Embodiment 2: A kind of hypoglycemic composition containing Caeberia japonica, calculated according to parts by weight, includes the following components: 20 parts of dry extracts of young leaves of Caeberia caebeia, 30 parts of dry powder of old leaves of Caeberia caebeia, and extracts of mulberry leaves 20 parts of dry powder, 10 parts of Caulis Spatholobus extract dry powder, 30 parts of mulberry buds, 10 parts of kudzu root extract dry powder and 30 parts of auxiliary materials.

[0039]Among them, the leaf age of the young leaves of Mujiang Yeke is 1 to 2 weeks, and the leaf age of the old leaves of Mu Jiang Ye Ke is more than 8 months. According to the mass calculation, the content of trilobatin in the dry powder of the young leaves of Mu Jiang Ye Ke is 1 to 5%. The content of phlorizin in the dry powder of the leaf extract is 2-8%, the content of 1-deoxynojirimycin in the dry powder of the mulberry leaf extract is 0.1-1%, the content of the total flavonoids in the...

Embodiment 3

[0045] Example 3: A blood-sugar-lowering composition containing Caeberia japonica, calculated in parts by weight, includes the following components: 20 parts of dry extract of young leaves of Caeberia phylloxera, 20 parts of dry powder of old leaf extracts of Caeberia phylloxera, and extract of mulberry leaves 20 parts of dry powder, 5 parts of Caulis Spatholobus extract dry powder, 30 parts of mulberry buds, 20 parts of kudzu root extract dry powder and 60 parts of auxiliary materials.

[0046] Among them, the leaf age of the young leaves of Mujiang Yeke is 1 to 2 weeks, and the leaf age of the old leaves of Mu Jiang Ye Ke is more than 8 months. According to the mass calculation, the content of trilobatin in the dry powder of the young leaves of Mu Jiang Ye Ke is 1 to 5%. The content of phlorizin in the dry powder of the leaf extract is 2-8%, the content of 1-deoxynojirimycin in the dry powder of the mulberry leaf extract is 0.1-1%, the content of the total flavonoids in the d...

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PUM

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Abstract

The invention belongs to the technical field of health-care food, and particularly relates to a blood sugar reducing composition containing lithocarpus litseifolius and a preparation method and an application method thereof. The blood sugar reducing composition is characterized by being prepared from the following components in parts by weight: 11 to 20 parts of lithocarpus litseifolius tender leaf extract dry powder, 11 to 30 parts of lithocarpus litseifolius old leaf extract dry powder, 5 to 20 parts of mulberry leaf extract dry powder, 5 to 10 parts of caulis spatholobi extract dry powder, 10 to 30 parts of mulberry bud dry powder, 10 to 20 parts of radix puerariae extract dry powder and 30 to 60 parts of auxiliary materials. According to the blood sugar reducing composition disclosed by the invention, through compound use of phlorizin in lithocarpus litseifolius old leaves and trilobatin in lithocarpus litseifolius tender leaves, a blood sugar source is reduced, and a blood sugar outlet path is increased; and meanwhile, 1-deoxynojirimycin in mulberry leaves is matched for inhibiting alpha-glycosidase and prompting insulin B cells to secrete insulin, so that the effect of reducing blood sugar is achieved.

Description

technical field [0001] The invention belongs to the technical field of health food, and in particular relates to a blood sugar-lowering composition containing Mujiang Yeke and its preparation method and application method. Background technique [0002] Diabetes Mellitus (DM) is a series of clinical syndromes caused by absolute or relative insufficiency of insulin in the body. The disease will also cause some complications during the development process, such as: hypoglycemia (Hypoglycemia), ketoacidosis (Ketoacidosis), nonketotic hyperosmolar coma (Nonketotic HyperosmolarComa), cardiovascular disease, chronic renal failure, retinopathy , neuropathy, and microvascular disease. [0003] Commonly used drugs for diabetes treatment mainly include: biological drugs, such as insulin (Insulin); chemical drugs, such as sulfonylureas (Sulfonylurea), biguanides (Biguanides), and glitazones (Glitazone); and natural drugs, such as Chinese herbal medicines. Due to the lack of mature non...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/10A23L33/105A23L2/38A61K36/605A61K9/22A61P3/10
CPCA23L33/10A23L33/105A23L2/38A61K36/49A61K36/605A61K36/486A61K36/20A61K9/2054A61P3/10A61K2236/333A61K2236/51A23V2002/00A61K2300/00A23V2200/328A23V2250/21A23V2250/5028A23V2250/5108A23V2250/5112A23V2250/511A23V2250/6422A23V2250/6418
Inventor 汤德良汤梦甜周卫军
Owner 良甜生物医药科技江苏有限公司
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