Polyhydroxypropyl arginine and its derivative polyhydroxy saccharide compound as well as preparation method and application thereof

A technology of polyhydroxypropyl arginine and hydroxypropyl arginine, which is applied in the field of daily chemical products, can solve the problem of low adsorption performance and deposition efficiency of moisturizing agent and skin/hair surface, and it is difficult to form an intermolecular network composite film structure. , can not form a complex hydrogen bond structure and other problems, to achieve excellent moisturizing effect, the preparation method is simple and easy to operate, and the preparation method is simple.

Active Publication Date: 2021-06-15
茵素科技(广州)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] (1) The adsorption performance and deposition efficiency of humectant and skin/hair surface are low;
[0010] (2) Modification and modification of biologically active sugars by biochemical methods are complex and have many application limitations;
[0011] (3) It is difficult to form

Method used

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  • Polyhydroxypropyl arginine and its derivative polyhydroxy saccharide compound as well as preparation method and application thereof
  • Polyhydroxypropyl arginine and its derivative polyhydroxy saccharide compound as well as preparation method and application thereof
  • Polyhydroxypropyl arginine and its derivative polyhydroxy saccharide compound as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] Example 1: an aqueous solution of 1% trehalose and 0.5% dihydroxypropyl arginine. Wherein, the structure of dihydroxypropyl arginine is as shown in formula I, wherein X=H, Y=H; that is, the structure of dihydroxypropyl arginine is as shown in formula X:

[0053]

Embodiment 2

[0054] Example 2: 1% trehalose, 0.5% glycerin aqueous solution.

[0055] Calculated as figure 1 As shown, when the system is in balance, there is a strong hydrogen bond between the molecules of Example 1, especially the hydrogen bond between the dihydroxypropyl arginine molecule and the biologically active sugar trehalose molecule, which is far greater than that between the glycerol molecule and the trehalose molecule. Hydrogen bonding between trehalose. By observing the intermolecular hydrogen bond conformation after the system reaches thermodynamic equilibrium, such as figure 2 As shown, there are mainly two hydrogen bond conformations between the dihydroxypropyl arginine molecule and the trehalose molecule used in the present invention, OH-N hydrogen bond and OH-H hydrogen bond. It does not exist in the system of small molecule glycerol and trehalose. The above results verified the special intermolecular strong hydrogen bond interaction mechanism between dihydroxypropyl...

Embodiment 3

[0061] Example 3: 1% trehalose aqueous solution.

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PUM

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Abstract

The invention discloses a polyhydroxypropyl arginine and its derivative polyhydroxy saccharide compound as well as a preparation method and application thereof. The polyhydroxypropyl arginine and its derivative and polyhydroxy saccharide are associated through hydrogen bonds to form a composite structure. The polyhydroxypropyl arginine and its derivative are active components formed by fusing glycerol, arginine and derivatives thereof; the glycerin is an efficient moisturizing component; the arginine and its derivative are natural moisturizing factor components, positive charges carried by the arginine and its derivative generate strong electrostatic adherence force with skin or damaged hair, combining with hydroxyl oxygen of the glycerin part and nitrogen groups of the arginine and the its derivative, hydrogen bonds can be easily formed with other hydrogen bond donors such as the skin or the damaged hair, and a long-acting and lasting moisturizing effect is achieved. A special composite structure and the cationic electrostatic interaction of the polyhydroxypropyl arginine and its derivative are further utilized to achieve more efficient interface adsorption performance, the moisturizing performance is good, the skin feeling is excellent, which can be applied to various daily chemical washing care and skin care formula systems.

Description

technical field [0001] The invention relates to the technical field of daily chemical products, in particular to a polyhydroxypropyl arginine and its derivative-polyhydroxy sugar complex as well as its preparation method and application. Background technique [0002] Efficient and long-lasting moisturizing properties are one of the important concerns of cosmetic formulations. Due to various external stimuli, including environmental damage, the skin epidermal cells are damaged, and the damaged skin epidermal cells are prone to dry skin and lack of water. Conventional small molecule moisturizers can bring immediate hydration to the skin, but cannot achieve long-lasting hydration. However, the use of closed moisturizers such as vaseline and white mineral oil in traditional cosmetics cannot give the skin sufficient air permeability, but it is easy to block pores, and oily skin is prone to pimples and acne. Bioactive sugar is a kind of natural active ingredients with good bioco...

Claims

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Application Information

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IPC IPC(8): A61K8/60A61K8/73A61K8/44A61Q19/00A61Q19/10A61Q1/14
CPCA61K8/60A61K8/735A61K8/73A61K8/736A61K8/442A61Q19/00A61K2800/10A61Q19/10A61Q1/14
Inventor 李东翠徐炎明
Owner 茵素科技(广州)有限公司
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