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Preparation method of intestinal stent

A kind of intestinal and part technology, applied in the field of preparation of intestinal stents, can solve problems such as inability to fit intestinal stents, inability to reduce internal stress of stents, difficult to cure, etc., to avoid complications and safety hazards, good application prospects, easy to The effect of the control operation

Pending Publication Date: 2021-07-02
孔海海
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Metal self-expanding stents, due to the excessive stress of the stent itself, cause secondary damage to the lesion itself, directly lead to intestinal fistula, and indirectly lead to peritonitis, which is difficult to cure
In addition, the tip of the metal wire that makes up the stent penetrates the intestinal wall, resulting in granulation hyperplasia; the tumor re-elongates inward through the stent gap, resulting in restenosis of the stent; moreover, the metal stent is too hard and is a permanent non-degradable material
After the operation, the patient will feel uncomfortable, especially in the state of motion, and the pain will increase, which also reduces the quality of life of the patient; even, the secondary operation rate is high due to pain, reocclusion, perforation, slippage and infection, and The intestinal stent cannot fit the individual anatomical structure, nor can it reduce the internal stress of the stent, and it is easy to fail in complex anatomical areas

Method used

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Experimental program
Comparison scheme
Effect test

Embodiment

[0014] A method for preparing an intestinal stent according to the present invention, establishing a three-dimensional model of the intestinal structure of an individual subject including the intestinal stenosis or obstruction part, adjusting it, and selecting the part corresponding to the stenosis or obstruction in the three-dimensional model , the diameter corresponding to the stenosis or obstruction in this part of the three-dimensional model is expanded by 5-7 mm as the virtual stent body;

[0015] 2) Based on the design of the virtual intestinal stent, use a 3D printed intestinal stent mold as the stent body, select polydioxane copper monofilament with a diameter of 0.1-0.5mm, and use a braiding machine to weave , the bending depth is 3-4mm, the knitting speed is 2.5-3.5m / min, the warp direction mixture filament density is 0.2-0.3mm, the weft direction mixture filament density is 0.4-0.5mm, and then the support The main body is decontaminated, cleaned and heat-set;

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PUM

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Abstract

The invention relates to the field of medical instruments, in particular to a preparation method of an intestinal stent. The method comprises the following steps: establishing a three-dimensional model of an intestinal tract structure of an individual object containing an intestinal tract stenosis or obstruction part, adjusting the three-dimensional model, selecting a part corresponding to the stenosis or obstruction part in the three-dimensional model, expanding the diameter of the part corresponding to the stenosis or obstruction part in the three-dimensional model by 5-7 mm, and taking the part as a virtual stent body. The preparation method is easy to control and operate; and compared with a copolymer system product, the preparation method is simple in process, higher in yield, more stable in quality and suitable for industrial production; and medical degradable materials are adopted as the raw materials, continuous inflammation or toxic reaction is not caused after implantation, complications and potential safety hazards caused by residues are effectively avoided, and good application prospects are achieved.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to a preparation method of an intestinal stent. Background technique [0002] Bowel stenting has been increasingly used as a nonsurgical palliative treatment for patients with intestinal strictures or intestinal obstruction. Although the traditional intestinal stent with a simple cylindrical structure is suitable for most of the flat parts of the esophagus and intestinal tract, but in curved parts such as the stomach-duodenum or intestinal-intestinal transition, the traditional stent and intestinal The actual structure fits poorly, which is very easy to cause sliding failure; [0003] In recent years, various studies have been carried out on the material, coating and drug-carrying aspects of intestinal stents. An ideal stent should have good histocompatibility, absorbability, and local targeted treatment of lesions. The stent-coated drug film technology is to apply the targeted ther...

Claims

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Application Information

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IPC IPC(8): A61F2/82B33Y10/00D01D5/00D04C1/06D04H1/728
CPCA61F2/82A61F2240/002A61F2240/005A61F2250/0067B33Y10/00D01D5/0015D04C1/06D04H1/728
Inventor 孔海海
Owner 孔海海