Preparation technology of chlorobenzene glyceryl ether

A technology for the preparation of chlorphenesin, which is applied in the direction of ether preparation, ester reaction to prepare ether, organic compound/hydride/coordination complex catalyst, etc., can solve the problem of inability to effectively control the reaction process and obtain chlorphenesin The problems such as instability of the production rate can be solved, and the effect of easy operation, simple preparation method and improved stability can be achieved.

Active Publication Date: 2021-07-23

菏泽新东方日化科技有限公司

3 Cites 0 Cited by

AI-Extracted Technical Summary

Problems solved by technology

[0007] In view of the above-mentioned related technologies, the inventor believes that the synthesis process of the above-mentioned te...

Method used

The data of comparative embodiment 9-11 and embodiment 8, and in conjunction with table 8 as known, the application is by controlling the kind of alkyl ammonium bromide, when alkyl ammonium chloride is dedecyl trimethyl ammonium bromide , octadecyltrimethylammonium bromide, and cetyltrimethylammonium bromide, the interaction between fumed silica, vitamin E, and alkylammonium bromide is stronger, thereby improving the The stability of the yield, among which cetyltrimethylammonium bromide has the strongest interaction with fumed silica and vitamin E.

The data of comparative example 12 and embodiment 11, and as can be known in conjunction with table 8, the application is by using dedecyl trimethyl ammonium bromide and hexadecyl trimethyl ammonium bromide composite, further improved The stability of the reaction between 3-chloro-1,2-propanediol and p-chlorophenol improves the stability of the yield of chlorophenesin.

The data of comparative example 13-15 and embodiment 12, and in conjunction with table 8 as can be known, the application further promotes fumed silica, vitamin E, alkylammonium bromide by controlling the specific surface area of fumed silica The synergistic effect between them improves the stability of the reaction be...

Abstract

The invention relates to the field of synthesis of cosmetic additives, and particularly discloses a preparation technology of chlorobenzene glyceryl ether. 3-chloro-1, 2-propylene glycol and parachlorophenol are adopted as main raw materials, and a catalyst is added to prepare the chlorobenzene glyceryl ether. The catalyst is prepared from, by weight, 3-12 parts of fumed silica, 1-10 parts of vitamin E and 3-7 parts of alkyl ammonium bromide. According to the preparation technology, the reaction process can be effectively controlled, and the stability of the yield of the chlorobenzene glyceryl ether is improved.

Application Domain

Organic-compounds/hydrides/coordination-complexes catalystsCatalytic reactions +1

Technology Topic

Alkyl bromidePropanediol +12

Image

Examples

Experimental program(10)
Comparison scheme(7)
Effect test(1)

Example Embodiment

[0037] Preparation 1

[0038] A catalyst, a preparation method is: 7 g of gas phase silica, 5 g vitamin E is dispersed in 15 g of anhydrous ethanol, followed by adding 5 g of alkyl bromide stirring well, heating to 40 ° C, continuingly stirring to anhydrous ethanol complete volatile That is, the catalyst is obtained.

[0039] The alkyl bromide is ammonium tetrapropropyl bromide, and the specific surface area of the gas phase silica is 350-410m. 2 / g, the vitamin E is α-tocopherol.

Example Embodiment

[0040] Preparation 2-3

[0041] Preparation Example 2-3 is based on Preparation Example 1, and the difference from Preparation Example 1 is only that the amount of raw materials is different, and Table 2 is specifically shown in Table 2.

[0042] Preparation example Preparation 1 Preparation 2 Preparation Example 3 Phase silica (g) 7 3 12 Vitamin E (g) 5 10 1 Alkyl bromide (G) 5 3 7

Example Embodiment

[0043] Preparation 4-6

[0044] Preparation Example 4-6 is based on Preparation Example 1, and the difference from the Preparation Example 1 is only in that the type of ammonium bromide used is different from the specifically shown in Table 3.

[0045] Preparation example Preparation 4 Preparation Example 5 Preparation 6 Alkyl bromide Tenalkyl trimethyl bromide Epternal alkyl trimethyl bromide Hexadalkyltrimel bromide

PUM

Property	Measurement	Unit
Specific surface area	170.0 ~ 230.0	m²/g

Description & Claims & Application Information

We can also present the details of the Description, Claims and Application information to help users get a comprehensive understanding of the technical details of the patent, such as background art, summary of invention, brief description of drawings, description of embodiments, and other original content. On the other hand, users can also determine the specific scope of protection of the technology through the list of claims; as well as understand the changes in the life cycle of the technology with the presentation of the patent timeline. Login to view more.

Classification and recommendation of technical efficacy words

Improve stability
Easy to prepare

Agent delivering system comprised of microparticle and biodegradable gel with an improved releasing profile and methods of use thereof

InactiveUS6287588B1increase stabilityimprove stability

Owner:BTG INT LTD

Preparation technology of chlorobenzene glyceryl ether

AI-Extracted Technical Summary

Problems solved by technology

Method used

Abstract

Image

Examples

Example Embodiment

Example Embodiment

Example Embodiment

PUM

Description & Claims & Application Information

Similar technology patents

Spinal implant with overlay

Traction control system including individual slip threshold reduction of the drive wheel on the outside of the curve

Parameter self-adaptive adjusting method and device

Monitoring system based on J2EE framework and method

Gemcitabine hydrochloride lyophilized powder injection

Classification and recommendation of technical efficacy words

Agent delivering system comprised of microparticle and biodegradable gel with an improved releasing profile and methods of use thereof

Gel stabilized nanoparticulate active agent compositions

Method for preparing silica aerogel material

Compositions and methods for protein design

Gas dielectric structure forming methods

Method for removing pollutants in sewage

Carbon nanofiber aerogel as well as preparation method and application thereof

Health care medicinal tea and preparation process thereof

Non-mercury catalyst for acetylene hydrochlorination and method of preparing the same

High-strength ultra-high-toughness concrete and preparation method thereof