56 results about "Alkyl bromide" patented technology

The invention relates to the technical field of material preparation, and particularly discloses a functionalized NH2-MIL-125 (Ti)-based material as well as a preparation method and application thereof. The preparation method comprises the following steps: firstly, under the action of an organic base catalyst, grafting an imidazole group to an amino group of NH2-MIL-125 (Ti) to obtain imidazole grafted NH2-MIL-125 (Ti); then, the imidazole modified NH2-MIL-125 (Ti) material and alkyl bromide are subjected to a coordination reaction, and the functionalized NH2-MIL-125 (Ti)-based material is obtained. The functionalized NH2-MIL-125 (Ti)-based material provided by the invention has the advantages of high adsorption capacity, high selectivity, high adsorption rate, high reduction efficiency, stable structure and the like in the aspect of adsorbing and reducing the noble metal, and a very potential solution is provided for recycling and reusing the noble metal.

The application discloses a kind of using cobalt catalyst by unreported double migration coupling strategy, realizes migration asymmetric nitrogen hetero Nozaki-Hiyama-Kishi (aza-NHK) reaction, and the selective preparation α-chiral (E)-allyl amine starting from simple and easy to obtain ortho halogen phenyl ethylene or corresponding E / Z-alkyl bromide or its mixture belongs to the field of organic chemistry and medicinal chemistry.The application under the action of metal cobalt source, ligand, organic additive, inorganic additive etc., makes cyclic sulfonamide and ortho alkenyl substituted aryl halide or alkenyl halide react in organic solvent, to obtain a series of polysubstituted olefins with excellent regioselectivity, stereoselectivity and good yield, which can be used as active drug molecules and important synthetic intermediates.The application uses cheap transition metal cobalt as catalyst, and uses ortho alkenyl substituted aryl iodine and cyclic sulfonamide as raw material, and the reaction condition is warm, simple operation, and good functional group compatibility.

The invention relates to the field of oilfield chemistry, and relates to a composite clean fracturing fluid for compact oil and gas reservoir fracturing and a fracture water plugging method. The composite clean fracturing fluid is prepared by compounding the following components in percentage by weight: 0.005 to 0.03 percent of nano particles, 0.5 to 3 percent of a viscoelastic surfactant, 0.5 to 2 percent of sodium p-toluenesulfonate and 94.97 to 98.995 percent of water. Wherein the nano particles are hydrophobic fluorine modified nano silicon dioxide, and the viscoelastic surfactant is octadecyl dimethyl hydroxypropyl ammonium bromide synthesized by N, N-dimethyl propanolamine and long-chain alkyl bromide. The composite clean fracturing fluid injection process is used for compact oil and gas reservoirs. The composite clean fracturing fluid has dual effects of fracturing and filtration loss reduction, and has higher shear resistance and viscoelasticity, and the used nanoparticles are prepared by a simple process, so that the composite clean fracturing fluid is beneficial to industrial popularization.

The invention relates to the technical field of flotation, in particular to a preparation process of a lepidolite ore flotation reagent, which comprises the following steps: reacting epoxidized soybean oil with N-methyltaurine, and reacting with alkyl bromide to obtain the lepidolite ore flotation reagent. The lepidolite ore flotation reagent contains a large amount of hydroxyl, quaternary ammonium salt cations and sulfonate anions, a unique betaine zwitterionic group is formed, the betaine zwitterionic group and the surface of the lepidolite ore have stronger hydrogen bond, static electricity and other adsorption effects, the flotation reagent is tightly and firmly adsorbed on the surface of the lepidolite ore, and the flotation efficiency is improved. And meanwhile, the flotation agent contains hydrophobic soybean oil molecular chains, so that the lepidolite ore has better hydrophobic flotation performance, and the recovery rate of the lepidolite ore is remarkably increased.

The invention discloses a preparation method and application of a catalyst for synthesizing 6-aminocapronitrile, and belongs to the field of catalysis. Comprising the following steps: mixing a carrier with an alkyl ammonium bromide solution, carrying out hydrothermal modification, drying I and roasting to obtain a modified carrier; mixing an active component precursor solution with the modified carrier, dipping, and drying II to obtain a catalyst precursor; and carrying out water vapor treatment on the catalyst precursor to prepare the catalyst for synthesizing 6-aminocapronitrile. The preparation method has the advantages of simple preparation process, low cost and easiness in large-scale production.

The invention discloses a hydroxy sulfobetaine gemini surfactant, which is simply recorded as DTH-n, the synthesis method comprises the following steps: (1) adding N, N-dimethylethylenediamine and alkyl bromide (carbon chain lengths are respectively 10, 12, 14 and 16) into a reaction container, carrying out reflux stirring at 70 DEG C for 16-20 hours by taking absolute ethyl alcohol as a solvent and KOH as an alkaline agent, carrying out suction filtration, carrying out rotary evaporation on filtrate to remove the solvent, dissolving a product into n-hexane, adding concentrated hydrochloric acid, stirring to separate out a white solid, carrying out suction filtration to obtain a solid gemini alkyl tertiary amine acidified substance, and drying the solid gemini alkyl tertiary amine acidified substance; dissolving the solid acidified substance in absolute ethyl alcohol, carrying out liquid separation, taking a lower-layer solution, and adding solid KOH to reduce the gemini alkyl tertiary amine acidified substance into an intermediate product gemini alkyl tertiary amine under the protection condition of normal hexane; and (2) adding the product, 3-chloro-2-hydroxypropane sodium sulfonate and an isopropanol aqueous solution as a solvent and sodium carbonate as an alkaline agent into a reaction container to maintain the pH value of the reaction solution at 8-10, carrying out reflux reaction at 90 DEG C for 48 hours, separating liquid, taking a lower-layer solution, evaporating in a vacuum oven to remove the solvent, dissolving residues in a 70% ethanol solution, carrying out suction filtration, standing the filtrate at 0 DEG C for 12 hours, separating out a viscous oil substance, and drying to obtain the product. Separating liquid, re-precipitating and purifying, evaporating in a vacuum oven to remove the solvent, and grinding to obtain a faint yellow powdery solid. According to the invention, a two-step method is adopted, the reaction steps are few, the operation is simple, the product is easy to separate and purify, and the surface activity and foam performance are excellent.

The present invention belongs to the field of tertiary oil recovery technology, and in particular to a zwitterionic drainage agent and a synthesis method thereof. The synthesis method is as follows: N-(2-aminoethyl)morpholine, ethanol, and benzyl chloride are sequentially added to a four-necked flask, the pH value is adjusted with a sodium hydroxide solution, heated, kept warm, and the pH is maintained to be not less than 8; sodium chlorosulfonate is added, heated to reflux, and the pH is maintained to be not less than 8; vacuum distillation, heating to dissolve, adjusting the pH value, extraction, and liquid separation are performed; the extract is transferred to a four-necked flask, dodecyl bromide and solid potassium carbonate are added, refluxed, filtered, the filtrate is cooled, a solid is precipitated, and dried overnight to obtain a product drainage agent. The present invention has the advantages of simple synthesis process, low surface interfacial tension, low critical micelle concentration, and high drainage rate.

The invention discloses a porphyrin dication covalent metal organic framework material as well as a preparation method and application thereof, and belongs to the technical field of biological medicines. The porphyrin dication covalent metal organic framework material is obtained by copolymerization of porphyrin with methyl, a bipyridine ruthenium (II) complex with aldehyde group and alkyl ammonium bromide. The porphyrin with methyl is tetra (6-methylpyridine-3-yl) porphyrin; the dipyridyl ruthenium (II) complex with the aldehyde group is tris (4, 4 '-dicarboxyaldehyde-2, 2'-dipyridyl) ruthenium (II); the alkyl ammonium bromide is 2-bromoethyl trimethyl ammonium bromide. According to the invention, the CRuP-COF is prepared by utilizing a Knoevenagel condensation reaction and an SN2 nucleophilic substitution reaction through a one-pot method. The CRuP-COF can be used as an intelligent therapeutic agent and can be used as a trinity intelligent treatment platform, photo-thermal / photodynamic / cation cascade collaborative treatment is realized, and healing of open bacterial infected wounds is remarkably accelerated.

The application belongs to the technical field of organic synthesis, and particularly relates to a benzimidazole alkyl bromide salt-anemarrhena saponin aglycone derivative, a preparation method and application thereof. The benzimidazole alkyl bromide salt-anemarrhena saponin aglycone derivative provided by the application has a structure shown in formula 1 or formula 2. The application combines an anemarrhena saponin aglycone skeleton and a benzimidazole skeleton, and the obtained benzimidazole alkyl bromide salt-anemarrhena saponin aglycone derivative with the structure shown in formula 1 or formula 2 has significant antitumor activity. The antitumor growth inhibition activity of the benzimidazole alkyl bromide salt-anemarrhena saponin aglycone derivative provided by the application is better than that of cisplatin (DDP), an anticancer drug.

The application provides a hydrophobic associating polymer and a preparation method thereof, and a polymer reinforced foam system, the hydrophobic associating polymer is copolymerized by a hydrophobic monomer and acrylamide and sodium acrylate; wherein the hydrophobic monomer is obtained by quaternary ammonium reaction of methacrylamidopropyl dimethyl amine and alkyl bromide with a molar ratio of 1:1-1.15. The foam system of the application has good foaming property and foam stability under strong oil wet conditions.

The invention belongs to the field of organic synthesis. The method comprises the following steps: mixing 1, 2-cyclohexane dicarboxylic acid anhydride, alkyl bromide and an organic solvent (N, N-dimethylacetamide) under the action of a transition metal catalyst bis ((1, 5-cyclooctadiene) nickel), a reducing agent (zinc powder) and a nitrogen ligand (2, 2 '-bipyridine ligand), and carrying out electrophilic reduction cross-coupling reaction to synthesize the gamma-alkyl ketonic acid compound. The cheap nickel is used as the metal catalyst, the use of an organic metal catalyst is avoided, the synthesis method is simple, the synthesis steps are few, the operation is convenient, the application range is wide, and various gamma-alkyl ketonic acid compounds can be synthesized.

The present invention belongs to the technical field of photocatalysts, and discloses a Cu 1.95 S 1‑x photocatalyst with surface Cu and S dual defect sites, its preparation method and application. By adding cetyltrimethylammonium bromide and hexamethylenetetramine to an ethylene glycol solution containing copper element, adding a certain amount of thioacetamide, stirring for a certain time at a certain temperature and then pouring it into a reaction kettle, and carrying out hydrothermal reaction at a certain temperature for a certain time, after washing and drying, a Cu 1.95 S 1‑x photocatalyst with surface Cu and S dual defect sites is obtained. The specific surface area of the photocatalyst prepared by the present invention is larger, and it has higher photocatalytic activity. In particular, the photocatalytic reduction activity of CO2 is enhanced, and the preparation method of the catalyst reduces the production cost and simplifies the production process. The prepared Cu 1.95 S 1‑x photocatalyst with surface Cu and S dual defect sites can photocatalytically reduce CO2 to CH4.

The invention belongs to the technical field of organic chemical synthesis, and discloses a synthesis method of an organosilicon compound. According to the invention, successful synthesis of the 1, 3-site double-silicon compound from acrylonitrile, chlorosilane and alkyl bromide at room temperature is realized for the first time, and the blank in the prior art is filled. The method provided by the invention has the advantages of mild process conditions, short flow, simple steps and wide substrate applicability, and meets industrial production requirements. Research finds that the yield of the product can reach 85%, and the generated alkyl silicon compound has wide application prospects in organic synthesis and drug research and development. Therefore, the method has important application value.

The invention provides a method for preparing 6-hydroxy-2H-pyran-3-ketone, which comprises the following steps: by taking meso-carboxyl phenyl porphyrin (H2TCPP) as a catalyst, oxygen (O2) as an oxidant, cetyl ammonium bromide (CTAB) and potassium phosphate (K3PO4) as auxiliaries and water as a reaction medium, carrying out catalytic oxidation reaction on furfuryl alcohol under natural sunlight for 1 hour, thereby preparing the 6-hydroxy-2H-pyran-3 (6H)-ketone (6-HPO). The 6-hydroxy-2H-pyran-3 (6H)-ketone is obtained through a one-step catalytic oxidation process under mild conditions, a cleaner and more economical catalytic process is achieved, the yield is as high as 98.94%, and the method is low in cost, few in by-product, environmentally friendly, high in atom economic efficiency and good in industrial application prospect.

The present invention provides a culture medium for amplifying hematopoietic cells having cell division ability, the culture medium containing a compound (I) represented by formula (1) or a physiologically acceptable salt thereof: in the formula (1), R1, R2, and R3 are each independently any one of hydrogen, a linear or branched C1-C4 alkyl group, bromine, and iodine, R4 is any one of a linear or branched C1-C4 alkyl group, bromine, and iodine, and R1, R2, and R3 are each independently any one of hydrogen, linear or branched C1-C4 alkyl groups, bromine, and iodine. R5 is any one of oxygen, methylene and a chemical bond, R6 is hydrogen or-NH2, R7 is hydrogen or-COOH, and R6 and R7 are not hydrogen at the same time.

The application discloses a kind of filter aids for reducing iron ore pulp moisture content and preparation method thereof, belong to filter aid technical field.The filter aid is with starch as matrix, cooperate bromoalkane, bromo quaternary ammonium salt and other raw materials, by pre-oxidation, alkaline activation, double bromination grafting and post-processing are obtained;Among them, bromoalkane is the normal monovalent alkyl bromide of carbon chain length 8-14, and bromo quaternary ammonium salt is 2-bromoethyl trimethyl ammonium bromide or 6-bromoethyl trimethyl ammonium bromide.The present application realizes the synchronous grafting of hydrophobic alkyl chain and cationic quaternary ammonium salt through covalent bond, which can not only destroy the mineral surface hydration film and convert attached water, but also flocculate fine particles and impurities, and optimize the pore structure of filter cake.The filter aid solves the defects of single function and poor synergy of traditional technology, significantly improves the filtration efficiency, reduces the moisture content of filter cake and the turbidity of filtrate, and the raw materials are environmentally friendly, the preparation process is simple, suitable for industrial production, and suitable for iron ore pulp solid-liquid separation filtering scene.

The invention relates to a method for synergistically catalyzing a decarbonylation alkylation reaction of alkyl aldehyde through nickel electrochemistry, which comprises the following steps: in an inert solvent, under the action of a metal catalyst, a ligand, an electrode and an electrolyte, carrying out catalytic reaction on an aldehyde compound containing unsaturated alkyl and alkyl bromide to obtain an alkane compound. According to the present invention, the non-activated alkyl aldehyde is adopted as the alkylation reagent, the raw materials are easily available, the operation is simple, the condition is mild, the expensive active metal catalyst or additive is not required to participate in the reaction, the good atom economy is provided, the high value-added alkane compound is obtained under the cheap and easily available current condition, and the synthesis process is environmentally friendly.

The invention discloses a filter aid for reducing the water content of iron ore slurry and a preparation method of the filter aid, and belongs to the technical field of filter aids. The filter aid is prepared by taking starch as a matrix and cooperating with raw materials such as brominated alkane and brominated quaternary ammonium salt through pre-oxidation, alkaline activation, dibromo-grafting and post-treatment. Wherein the alkyl bromide is normal monoalkyl bromide with the carbon chain length of 8-14, and the brominated quaternary ammonium salt is 2-bromoethyl trimethyl ammonium bromide or 6-bromoethyl trimethyl ammonium bromide. Synchronous grafting of hydrophobic alkyl chains and cationic quaternary ammonium salt is achieved through covalent bonds, hydration membranes on the surfaces of minerals can be destroyed, attached water can be converted, fine particles and impurities can be flocculated, and the pore structure of a filter cake is optimized. The filter aid overcomes the defects that a traditional technology is single in function and poor in synergism, the filtering efficiency is remarkably improved, filter cake moisture and filtrate turbidity are reduced, raw materials are environmentally friendly, the preparation technology is simple, and the filter aid is suitable for industrial production and suitable for iron ore slurry solid-liquid separation and filtering scenes.

The invention provides a preparation method of polystyrene with controllable molecular weight, which comprises the following steps: under the protection of inert atmosphere, adding a reducing agent into a water-free and oxygen-free organic solvent, then adding a styrene monomer, a catalyst and a dormancy initiator, and controlling the temperature to carry out polymerization reaction; after the reaction is finished, terminating the reaction, and carrying out post-treatment to obtain polystyrene; wherein the catalyst is a copper bromide / pentamethyldiethylenetriamine complex; the dormancy initiator comprises any one or a combination of at least two of alkyl chloride, alkyl bromide or alkyl iodide; the reducing agent is graphene oxide grafted with a phenolic hydroxyl group, and the active component phenolic hydroxyl group is grafted on the carrier graphene oxide. The supported reducing agent is adopted, the dynamic environment of polymerization reaction is fundamentally changed, and the free radical concentration in the system is controlled at an extremely low level, so that the occurrence rate of side reaction is fundamentally and greatly reduced, and controllable molecular weight is realized; belongs to the technical field of organic synthesis.

The invention provides a hydrophobic associated polymer, a preparation method thereof and a polymer reinforced foam system. The hydrophobic associated polymer is formed by copolymerization of a hydrophobic monomer, acrylamide and sodium acrylate. Wherein the hydrophobic monomer is obtained by carrying out quaternization reaction on methacrylamide propyl dimethyl amine and alkyl bromide in a molar ratio of 1: (1-1.15). The foam system provided by the invention has good foamability and foam stability under strong oil-wet conditions.

The invention discloses a polysiloxane-based polyurethane / quaternary ammonium-zwitterionic pressure-sensitive adhesive double-layer film as well as a preparation method and application thereof. The preparation method comprises the following steps: reacting amino-terminated polysiloxane with isophorone diisocyanate, hexamethylene diisocyanate and isophorone diamine to obtain a polysiloxane-based polyurethane elastomer; the preparation method comprises the following steps: reacting polyethylene glycol, polytetramethylene ether glycol, isophorone diisocyanate and N-methyldiethanolamine to obtain a polyurethane pressure-sensitive adhesive containing a tertiary amine group, and reacting the polyurethane pressure-sensitive adhesive with 1, 3-propane sultone and alkyl bromide to obtain a quaternary ammonium-zwitterionic polyurethane pressure-sensitive adhesive; and finally, coating the polysiloxane-based polyurethane elastomer with the quaternary ammonium-zwitterionic polyurethane pressure-sensitive adhesive, and evaporating the solvent to obtain the double-layer film. The raw materials are simple and easy to obtain, and the obtained product has good biocompatibility, adhesion, vapor permeability, water absorption, antibacterial property and protein adsorption resistance, so that the product is suitable for being used as a wound dressing for chronic infection.

The present invention relates to the technical field of polyurethanes, and discloses a TPU antistatic masterbatch formula and method, including 100 parts by weight of polyol, 10.7-16.2 parts by weight of diisocyanate, 8.6-15.2 parts by weight of tertiary amine sulfone chain extender, 1.4-3.7 parts by weight of alkyl bromide, 0.3-0.4 parts by weight of dibutyltin dilaurate, and 0.1-0.13 parts by weight of antioxidant; the present invention introduces an antistatic quaternary ammonium salt group into the main chain of the polyurethane, and the obtained TPU antistatic masterbatch has low surface resistivity, good electrical conductivity, and excellent antistatic performance. In addition, the introduction of a heat-resistant diphenyl sulfone structure is conducive to improving the heat resistance of the polyurethane TUP.

The invention discloses a method for constructing an aromatic derivative through a reductive cross-coupling reaction, and belongs to the technical field of organic synthesis. The preparation method comprises the following steps: co-dissolving aryl bromide, alkyl bromide, an iron-containing reagent, a ligand, a reducing agent and alkali in a solvent, and reacting at 45-100 DEG C for 14-18 hours to obtain an aromatic derivative; wherein the iron-containing reagent is ferrous bromide, the ligand is tetramethylethylenediamine, the alkali is lithium methoxide, the reducing agent is bis (pinacolato) diboron, and the solvent is methyl tert-butyl ether. Cheap and low-toxicity metal iron is used for replacing other transition metals for catalytic reaction, meanwhile, aryl bromide and alkyl bromide which are easy to obtain are used as reaction raw materials, construction of carbon-carbon bonds is completed through one-step reaction, and the aromatic derivative is obtained; the technical problems that precious metal or multi-metal catalysis is needed for alkyl modification of traditional transition metal catalysis aromatic compounds, and reaction substrates are difficult to obtain are solved.

The invention belongs to the technical field of organic chemical synthesis, and discloses a method for catalytically synthesizing a 1, 3-site silicon-boron compound by using transition metal. According to the invention, the successful synthesis of the 1, 3-site silicon-boron compound from acrylonitrile, halogenated silane and alkyl bromide at room temperature is realized for the first time, and the blank in the prior art is filled. The method provided by the invention has the advantages of mild process conditions, short flow, simple steps and wide substrate applicability, and meets industrial production requirements. Research finds that the yield of the product can reach 85%, and the generated alkyl silicon boron compound has wide application prospects in organic synthesis and drug research and development. Therefore, the method has important application value.

The present invention belongs to the field of photovoltaic materials. The present invention relates to a macromolecular light conversion agent and a preparation method thereof, a photovoltaic encapsulation light conversion adhesive film, and the preparation method of the macromolecular light conversion agent comprises the following steps: subjecting benzotriazole to a substitution reaction with liquid bromine to obtain an intermediate product I; subjecting the intermediate product I to a substitution reaction with a bromoester to obtain an intermediate product II; subjecting the intermediate product II to a coupling reaction with a vinyl phenyl boronic acid derivative to obtain an intermediate product III; subjecting bromofluorene to a substitution reaction with an alkyl bromide to obtain an intermediate product IV; subjecting the intermediate product IV to a coupling reaction with a vinyl phenyl boronic acid derivative to obtain an intermediate product V; subjecting the intermediate product III to an intermediate product V to a free radical polymerization reaction to obtain a macromolecular light conversion agent. The self-made macromolecular light conversion agent effectively solves the problems of narrow and single absorption peak, low light utilization, poor stability, and easy precipitation of the organic light conversion agent benzotriazole commonly used in the current photovoltaic plugging eye adhesive film.

The invention discloses a micromolecular sizing agent, a synthesis method thereof, a sizing agent solution and application, and belongs to the technical field of papermaking chemicals. The sizing agent has a double-long-chain secondary amine structure as shown in a general formula R2N (C3H6) N (CH3) 2, in which R is long-chain alkyl CnH2n + 1, and n is 14, 16 or 18. The synthesis method of the micromolecular sizing agent comprises the following steps: mixing 3-dimethylaminopropylamine and alkyl bromide in a molar ratio of 1: (2.0-2.5), and adding absolute ethyl alcohol as a solvent to prepare a mixture; and carrying out a heating reflux reaction on the mixture, and after the reaction is completed, sequentially carrying out reduced pressure distillation and recrystallization to prepare the micromolecular sizing agent. A brand new physical and chemical mechanism of electrostatic anchoring-hydrophobic shielding is utilized, and cellulose-based materials such as paper and the like are efficiently and instantly endowed with excellent hydrophobic performance under a neutral or alkaline mild condition.

The invention specifically discloses a negative electrode material, a preparation method thereof and a battery using the negative electrode material. The negative electrode material comprises titanium diselenide, long-chain alkyl ammonium bromide and a carbon material. The long-chain alkyl ammonium bromide comprises at least one of hexadecyl trimethyl ammonium bromide, octadecyl trimethyl ammonium bromide and dodecyl trimethyl ammonium bromide; the carbon material comprises at least one of carbon spheres and carbon nanotubes. The anode material disclosed by the invention is excellent in electrochemical performance and cycle performance.

The application discloses a method for preparing star-shaped block copolymer based on light-controlled in-situ bromine-iodine conversion reversible-deactivation radical polymerization, which comprises the following steps: mixing and dissolving MMA, alkyl bromide initiator, iodide and amine catalyst, and obtaining star-shaped homopolymer through BIT-RDRP reaction under blue light irradiation; mixing and dissolving PEGMA300, iodide and amine catalyst, mixing with the star-shaped homopolymer, and obtaining amphiphilic star-shaped block copolymer through BIT-RDRP reaction under blue light irradiation. The BIT-RDRP reaction is adopted, and the BIT-RDRP reaction is introduced into a continuous flow micro-tube reactor to prepare amphiphilic star-shaped block copolymer with controllable block ratio; the method has the advantages of mild conditions, simple components and high efficiency, can realize continuous preparation, and provides a simple and efficient method for controllable large-scale preparation of star-shaped block copolymer.

The invention relates to the technical field of bactericides, and discloses a preparation process of a bactericide, which comprises the following steps: carrying out substitution reaction on secondary amine in N1, N3-diacetyl diethylenetriamine and 1, 4-dibromobutane to obtain an intermediate product 1, hydrolyzing amido bonds of the intermediate product 1 under the action of a water system and sodium hydroxide to obtain an intermediate product 2, and carrying out reaction on the intermediate product 2 and the intermediate product 3 to obtain the bactericide. The preparation method comprises the following steps: carrying out a ring-opening reaction on cinnamyl aldehyde and aziridine to obtain an intermediate product 3, carrying out an aldehyde-amine condensation reaction to condense carbonyl of cinnamyl aldehyde and amino of the intermediate product 3 to obtain an intermediate product 4, and carrying out a quaternization reaction on tertiary amine in the intermediate product 4 and alkyl bromide to obtain the bactericide. The bactericide prepared by the invention has an excellent bactericidal effect on escherichia coli and staphylococcus aureus, and the highest bactericidal effect can reach 99.9%.

The present invention discloses a porphyrin-based dicationic covalent metal-organic framework material, its preparation method and application, belonging to the technical field of biomedicine. The porphyrin-based dicationic covalent metal-organic framework material is obtained by copolymerizing a porphyrin with a methyl group, a ruthenium(II) bipyridine complex with an aldehyde group and an alkyl ammonium bromide. The porphyrin with a methyl group is tetrakis(6-methylpyridin-3-yl)porphyrin; the ruthenium(II) bipyridine complex with an aldehyde group is tris(4,4'-dicarboxaldehyde-2,2'-bipyridine)ruthenium(II); the alkyl ammonium bromide is 2-bromoethyltrimethylammonium bromide. The present invention prepares CRuP-COF by a one-pot method using the Knoevenagel condensation reaction and the SN2 nucleophilic substitution reaction. CRuP-COF can be used as an intelligent therapeutic agent and can serve as a "trinity" intelligent therapeutic platform to achieve photothermal / photodynamic / cationic cascade synergistic therapy, significantly accelerating the healing of open bacterial infection wounds.