Preparation method of mussaenda pubescens heat-clearing preparation

A kind of jade leaf golden flower and preparation technology, which is applied in the directions of antipyretics, anti-inflammatory agents, pharmaceutical formulations, etc., can solve the problems of easy sticking of materials to the inner wall of equipment, low content of active components in finished products, and difficulty in disintegration of finished products, etc. Oral bioavailability, improved powder fluidity, and the effect of avoiding thermal degradation

Inactive Publication Date: 2021-09-24
GUANGXI CHUNZHENGTANG PHARM CO LTD
View PDF2 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of this application is to provide a preparation method of Yuye Jinhua heat-clearing preparation, aiming to solve the problems in the prior art that in the preparation process of traditional Chinese

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of mussaenda pubescens heat-clearing preparation
  • Preparation method of mussaenda pubescens heat-clearing preparation

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0023] The first aspect of the embodiment of the present application provides a preparation method of Yuyejinhua heat-clearing preparation, comprising the following steps:

[0024] S01. Provide 14-19 parts of Yuye Jinhua heat-clearing preparation extract extract, 28-42 parts of surfactant, 15-30 parts of sweet taste additive, 2-3 parts of β-cyclodextrin, 0.25-0.5 part of Yuye Jinhua Qingre The preparation extracts volatile oil, 4 to 7 parts of lubricant, and 1 to 5 parts of adhesive;

[0025] S02. Mix β-cyclodextrin and water to form a saturated solution of β-cyclodextrin, perform the first mixing treatment with the volatile oil extracted from Yuye Jinhua Qingre preparation and the saturated solution of β-cyclodextrin to obtain the first mixture, and carry out the first mixture Purification treatment to obtain volatile oil clathrate;

[0026] S03. Drying and pulverizing the Jade Leaf and Golden Flower heat-clearing preparation extract extract powder to obtain the Jade Leaf an...

Embodiment 1

[0067] Yuyejinhua heat-clearing preparation and preparation method

[0068] The preparation method of Yuye Jinhua heat-clearing preparation is adopted to prepare the Yuye Jinhua heat-clearing preparation, and the preparation method comprises the following steps:

[0069] Provide 14 parts of Yuye Jinhua heat-clearing preparation extract extract, 28 parts of inulin lauryl carbamate, 15 parts of lactose, 2 parts of β-cyclodextrin, 0.25 parts of Yuye Jinhua heat-clearing preparation extract volatile oil, 4 parts of porous silica , 1 part of absolute ethanol;

[0070] Mix β-cyclodextrin and water to form a saturated solution of β-cyclodextrin, heat it to 40°C with a constant temperature water bath, and extract volatile oil from Yuye Jinhua Qingre preparation under stirring (900r / min) (β-cyclodextrin: jade Extract volatile oil from Yejinhua heat-clearing preparation = 7:1) Add dropwise, react for 30 minutes, let stand at room temperature for 24 hours, filter with suction, wash the wh...

Embodiment 2

[0082] Yuyejinhua heat-clearing preparation and preparation method

[0083] In the preparation method of the Yuye Jinhua heat-clearing preparation in Example 2, "β-cyclodextrin: Yuye Jinhua heat-clearing preparation extracts volatile oil = 7:1" in Example 1 is replaced by "β-cyclodextrin: Yuye Jinhua heat-clearing preparation extracts Volatile oil = 11:1", other unchanged, prepared Yuye Jinhua heat-clearing preparation.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Particle sizeaaaaaaaaaa
Particle sizeaaaaaaaaaa
Particle sizeaaaaaaaaaa
Login to view more

Abstract

The invention provides a preparation method of a mussaenda pubescens heat-clearing preparation. The method comprises the following steps: mixing beta-cyclodextrin and water to form a beta-cyclodextrin saturated solution, extracting volatile oil from the mussaenda pubescens heat-clearing preparation, and carrying out first mixing treatment and purification treatment on the volatile oil and the beta-cyclodextrin saturated solution to obtain a volatile oil inclusion compound; drying and crushing the mussaenda pubescens heat-clearing preparation extract extractum to obtain mussaenda pubescens heat-clearing preparation extract powder, and performing second mixing treatment on the mussaenda pubescens heat-clearing preparation extract powder, a surfactant, a lubricant and an organic solvent to obtain a second mixture; performing spray drying and coarse granulation on the second mixture to obtain coarse preparation particles; and mixing and granulating the coarse preparation particles, a sweet additive, a volatile oil clathrate compound and an adhesive to obtain the mussaenda pubescens heat-clearing preparation. The obtained finished product preparation has strong effects of clearing heat, relieving exterior syndrome, relieving sore-throat and diminishing swelling, and the preparation process is simple, few in flow and beneficial to effectively improving the production efficiency.

Description

technical field [0001] The application belongs to the technical field of traditional Chinese medicines, and in particular relates to a preparation method of Yuyejinhua heat-clearing preparation. Background technique [0002] Acute pharyngitis is acute inflammation of pharyngeal mucosa, submucosal tissue and lymphoid tissue. This disease is often the prodromal symptom of various other infectious diseases. It can occur alone, and it is often secondary to acute rhinitis or tonsillitis. It occurs frequently in autumn and winter. And the turn of winter and spring; often due to cold, excessive fatigue, excessive smoking and alcohol, etc., the systemic and local resistance decreases, and pathogenic microorganisms take advantage of the weak point to cause the disease; malnutrition, chronic heart, kidney, joint diseases, life and Poor working environment and so on are all susceptible to this disease. The pathogenic microorganisms are mainly hemolytic streptococcus, pneumococcus, infl...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K36/808A61K36/74A61K9/16A61K47/40A61P11/04A61P29/00A61K35/413
CPCA61K36/74A61K36/19A61K36/744A61K36/21A61K36/808A61K35/413A61K9/1652A61P29/00A61P11/04A61K2236/331A61K2300/00Y02A50/30
Inventor 管悦琴刘亚东罗雪峰
Owner GUANGXI CHUNZHENGTANG PHARM CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap