Cream for treating herpes zoster and preparation method of cream
A herpes zoster and formula technology, applied in the field of medicine, can solve problems such as being unsuitable for clinical promotion and application, unclear preparation method, inaccurate curative effect, etc., and achieve the effects of no adverse reactions and sequelae, no toxic side effects, and significant therapeutic effects.
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Examples
Embodiment 1
[0024] The preparation of embodiment 1 composition of the present invention
[0025] (1) Pulsatilla extract extract: Pulsatilla medicinal material is reflux extracted 3 times with 70% ethanol with 8 times of v / w, ml / g, each time for 2 hours, the combined extracts are filtered, and the filtrate is concentrated to 60°C with a relative density of 1.05- 1.10, the filtrate was dissolved in water, passed through AB-8 resin, eluted with 50% ethanol, and the eluate was concentrated under reduced pressure to a thick paste with a relative density of 1.20 at 60°C.
[0026] (2) Oil phase: 8g of stearic acid, 4g of vaseline, 1g of lanolin, 8g of glyceryl monostearate, heated to 80°C to melt into an oil phase, stirred until uniform, and kept warm for later use.
[0027] (3) Water phase: 8 g of glycerin, 4 g of triethanolamine, and 0.1 g of ethylparaben, heated to 80° C. to dissolve into water phase, stirred until uniform, and set aside for later use.
[0028] (4) Under stirring, slowly add...
Embodiment 2
[0029] The preparation of embodiment 2 compositions of the present invention
[0030] (1) Pulsatilla extract extract: Pulsatilla medicinal material is extracted 3 times with 10 times the amount of 70% ethanol under reflux, each time for 2 hours, the combined extracts are filtered, the filtrate is concentrated to 60 °C relative density 1.05-1.10, the filtrate is dissolved in water and filtered AB-8 resin was eluted with 50% ethanol, and the eluate was concentrated under reduced pressure to a thick paste with a relative density of 1.20 at 60°C.
[0031] (2) Oil phase: stearic acid 10g, vaseline 5g, lanolin 2g, glyceryl monostearate 9g, heated to 80°C to melt into an oil phase, stirred until uniform, kept warm for later use.
[0032] (3) Water phase: 10 g of glycerin, 6 g of triethanolamine, and 0.2 g of ethylparaben were heated to 80° C. to dissolve into the water phase, stirred until uniform, and set aside for later use.
[0033] (4) Under stirring, slowly add the water phase ...
Embodiment 3
[0034] The preparation of embodiment 3 compositions of the present invention
[0035] (1) Pulsatillae extract extract: Pulsatilla medicinal material is extracted 3 times with 12 times the amount of 70% ethanol under reflux, each time for 2 hours, the combined extracts are filtered, and the filtrate is concentrated to a relative density of 1.05-1.10 at 60°C. The filtrate is dissolved in water and filtered. AB-8 resin was eluted with 50% ethanol, and the eluate was concentrated under reduced pressure to a thick paste with a relative density of 1.20 at 60°C.
[0036] (2) Oil phase: 12g of stearic acid, 6g of vaseline, 3g of lanolin, 10g of glyceryl monostearate, heated to 80°C to melt into an oil phase, stirred until uniform, kept warm for later use.
[0037] (3) Water phase: 12 g of glycerin, 8 g of triethanolamine, and 0.3 g of ethylparaben were heated to 80° C. to dissolve into the water phase, stirred until uniform, and set aside for later use.
[0038] (4) Under stirring, s...
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Description
Claims
Application Information
- IPC
- A61K36/71; A61K9/06; A61K9/08; A61K9/70; A61P31/22
- CPC
- A61K36/71; A61K9/06; A61K9/08; A61K9/7007; A61K9/0014; A61K47/44; A61P31/22; A61K2236/333
- Inventors
- 杨世林; 苏柘僮