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Application of traditional Chinese medicine composition in preparation of anti-inflammatory medicine and/or immunomodulatory medicine

A technology of immunomodulatory drugs and anti-inflammatory drugs, which can be used in drug combinations, anti-inflammatory agents, and resistance to vector-borne diseases, etc., can solve problems such as drug listing, and achieve the effect of regulating immunity and restoring balance.

Active Publication Date: 2021-11-16
BEIJING CHINESE MEDICINE HOSPITAL AFFILIATED CAPITAL MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, there are no related drugs on the market

Method used

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  • Application of traditional Chinese medicine composition in preparation of anti-inflammatory medicine and/or immunomodulatory medicine
  • Application of traditional Chinese medicine composition in preparation of anti-inflammatory medicine and/or immunomodulatory medicine
  • Application of traditional Chinese medicine composition in preparation of anti-inflammatory medicine and/or immunomodulatory medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] This embodiment provides a Chinese medicine composition, including 15g of bran-fried Atractylodes atractylodes, 10g of raw ephedra, 15g of patchouli, 6g of mountain bean root, 10g of catechu, 15g of shegan, 10g of brocade lantern and 10g of raw licorice.

[0068] This embodiment provides a pharmaceutical preparation comprising the above-mentioned traditional Chinese medicine composition, and its preparation method is as follows: take bran-fried Chinese herb and patchouli according to the prescription weight of the traditional Chinese medicine composition, add 10 times the amount of water, and extract the volatile oil by steam distillation Extract for 2 hours, collect volatile oil, and set aside; collect the distilled water in another device, set aside; take raw ephedra, shegan, mountain bean root, catechu, brocade lantern, and raw licorice according to the prescription, add water and decoct three times, add 10 for the first time Double the amount of water, decoct for 1 h...

Embodiment 2

[0070] This example provides a traditional Chinese medicine composition, which includes 13g of bran-fried Atractylodes atractylodes, 8g of raw ephedra, 18g of Huoxiang, 4g of mountain bean root, 8g of catechu, 18g of shegan, 8g of brocade lantern and 13g of licorice.

[0071] This embodiment provides a pharmaceutical preparation comprising the above-mentioned traditional Chinese medicine composition. Its preparation method is as follows: according to the prescription weight of the traditional Chinese medicine composition, take bran-fried Atractylodes atractylodis, Huoxiang, raw ephedra, Shegan, Shandougen, catechin, broccoli Lanterns and licorice, add water to decoct twice, add 10 times the amount of water for the first time, decoct for 6 hours, add 5 times the amount of water for the second time, decoct for 0.5 hours, combine the decoction liquid, filter, and the filtrate and the above distillation The water and liquid are combined, concentrated under reduced pressure to a thi...

Embodiment 3

[0073] This embodiment provides a traditional Chinese medicine composition, including 18g of Atractylodes atractylodes Rhizome, 13g of Raw Ephedra, 13g of Huoxiang, 9g of Shandougen, 13g of Catechin, 13g of Shegan, 13g of Jindenglan and 8g of Licorice.

[0074]This embodiment provides a pharmaceutical preparation comprising the above-mentioned traditional Chinese medicine composition, and its preparation method is as follows: take Artemisia annua, Atractylodes atractylodes and Huoxiang according to the prescription weight of the traditional Chinese medicine composition, add 20 times the amount of water, and extract the volatile oil by steam distillation , the extraction time is 3 hours, collect the volatile oil, and set aside; the distilled water liquid is collected in another device, set aside; according to the prescription, take raw ephedra, raw gypsum, Bupleurum, astragalus, verbena and licorice, add water and decoct twice, add water for the first time 3 times the amount of ...

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Abstract

The invention relates to the field of traditional Chinese medicine, in particular to application of a traditional Chinese medicine composition in preparation of anti-inflammatory medicine and / or immunomodulatory medicine, the traditional Chinese medicine composition is obtained by repeatedly optimizing composition and content of compound traditional Chinese medicine through clinical research and fundamental research, in the formula, rhizoma atractylodis is used as a monarch medicine, and herba ephedrae and agastache rugosus are combined as a ministerial medicine. And blackberry lily, subprostrate sophora, catechu and calyx seu fructus physalis are used as adjuvant drugs. And finally, liquorice is used as a conductant drug. Atractylodes lancea can resolve dampness, ephedra can sweate and dispel cold, and wrinkled gianthyssop herb can warm the blackberry lily, the vietnamese sophora root, the catechu and the calyx seu fructus physalis clear heat and relieve sore-throat, the liquorice is used for harmonizing the medicines, and the medicines jointly have the effects of resolving dampness, tonifying spleen, clearing away heat and toxic materials and have a positive regulation effect on body immunity.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to the application of a traditional Chinese medicine composition in the preparation of immunomodulatory medicines. Background technique [0002] The body's immune system plays an important role in clearing cancerous tissue and pathogen invasion, and cellular immunity is an important part of the body's immune system. In cellular immunity, lymphoid T cells and lymphoid B cells occupy a central position, and lymphoid T cells are mainly divided into CD8 and CD8 cells according to their surface markers. + Cytotoxic T cells, CD4 + helper T cells, CD4 + CD25 + regulatory T cells, etc. According to different surface markers, lymphoid B cells are mainly divided into CD45RB cells, B1 cells, B2 cells, etc. Lymphatic T cells and lymphoid B cells express a variety of cytokines, including IL-IR, IL-2R, IL-4, IL-6, IL-10, etc. Under normal circumstances, the body's immune respons...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P29/00A61P37/02
CPCA61K36/284A61K36/17A61K36/532A61K36/489A61K36/48A61K36/88A61K36/81A61K36/484A61P29/00A61P37/02A61K2236/331A61K2236/39A61K2236/333A61K2236/51A61K2300/00Y02A50/30
Inventor 郭玉红崔煦然刘清泉
Owner BEIJING CHINESE MEDICINE HOSPITAL AFFILIATED CAPITAL MEDICAL UNIV
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