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Composition for improving skin care property of hyaluronic acid or salt thereof and method thereof

A technology of hyaluronic acid and sodium hyaluronate, which is applied in skin care preparations, pharmaceutical formulas, cosmetics, etc., can solve problems such as keratinocyte expansion and brick wall structure relaxation, so as to improve moisture retention, reduce negative effects, The effect of increasing the moisture content

Active Publication Date: 2022-02-15
BEIJING BLOOMAGE HYINC TECH CO LTD +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the water molecules themselves have a negative effect on the moisture retention of the skin, i.e., the water molecules bind to the keratinin of the skin, causing the keratinocytes to swell, thereby loosening the brick wall structure of the skin
Therefore, the moisturizing and skin care properties of hyaluronic acid or its salts cannot be maximized.

Method used

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  • Composition for improving skin care property of hyaluronic acid or salt thereof and method thereof
  • Composition for improving skin care property of hyaluronic acid or salt thereof and method thereof
  • Composition for improving skin care property of hyaluronic acid or salt thereof and method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0090] Mix the oil phase and sodium hyaluronate aqueous phase solution to obtain an emulsion, wherein the composition of the aqueous phase solution of sodium hyaluronate is shown in Table 2, and the composition of the oil phase is shown in Table 3 to make an emulsion The content of the oil phase in the emulsion is shown in Table 4, which is case-18-case-26.

experiment example 1

[0102] Experimental example 1 skin water content test method

[0103] This experiment selected 15 subjects, aged between 18-65 years old, except those who were pregnant or breastfeeding; those without serious systemic diseases, immune deficiency and autoimmune diseases; those who had not received skin treatment, beauty treatment and Other tests that may affect the results; no active allergic diseases; no highly sensitive constitution; no use of hormone drugs and immunosuppressants in the past month; no test site currently or in the past 3 months participating in other clinical experimenter.

[0104] The skin moisture content test was carried out on the forearm of the test subject, and the whole test process was carried out in a room at 20-22°C and 40%-60% relative humidity.

[0105] Volunteers were not allowed to touch the forearm with water for 3 hours before the test, and the flexor side of the forearm was wiped with facial tissue before the test. Three 3x 3cm square test ...

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Abstract

The invention discloses a composition and a method for improving skin care property of hyaluronic acid or salt thereof. The method comprises the following steps: mixing an oil phase with hyaluronic acid or salt water phase solution thereof to obtain emulsion, wherein the oil phase is triglyceride with fully alkylated side chains, the viscosity of the oil phase is less than 85 centipoises, and the mass percent of the oil phase in the emulsion is 45-75%. According to the method and the composition provided by the invention, the moisture retention property of the hyaluronic acid or the salt thereof can be improved, namely, the negative influence of water on the moisture retention property of the hyaluronic acid or the salt thereof is reduced, so that the moisture retention property of the hyaluronic acid or the salt thereof is fully exerted, and the skin barrier function can be improved.

Description

technical field [0001] The invention relates to the technical field of hyaluronic acid, in particular to a composition and a method for improving the skin care properties of hyaluronic acid or its salt. Background technique [0002] Hyaluronic acid or its salt is a natural skin moisturizer, and its application in cosmetics must be dissolved in the water phase. However, the water molecules themselves have a negative effect on the moisture retention of the skin, i.e., the water molecules bind to the keratinin of the skin, causing the keratinocytes to swell, thereby loosening the brick wall structure of the skin. Therefore, the moisturizing and skin care properties of hyaluronic acid or its salt cannot be brought into full play. Contents of the invention [0003] In view of the above problems, the present invention provides a method and composition for improving the skin care properties of hyaluronic acid or its salts, which can reduce the negative impact of water on the moi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/73A61K8/92A61K8/37A61Q19/00
CPCA61K8/735A61K8/922A61K8/375A61Q19/00
Inventor 刘喆王嫄
Owner BEIJING BLOOMAGE HYINC TECH CO LTD
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