Supercharge Your Innovation With Domain-Expert AI Agents!

External skin preparation containing povidone iodine and used for treating psoriasis

A technology of povidone-iodine and psoriasis, which is applied in the field of medicine, can solve the problems of undetected psoriasis, achieve the effect of reducing psoriatic skin and nail damage, reducing skin plaques and scales, and reducing reinfection

Pending Publication Date: 2022-04-05
IVEW THERAPEUTICS (ZHUHAI) CO LTD
View PDF2 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After searching the patents and literature at home and abroad, no relevant patents and literature reports on the combination of povidone-iodine and film-forming agent for the treatment of psoriasis were found

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • External skin preparation containing povidone iodine and used for treating psoriasis
  • External skin preparation containing povidone iodine and used for treating psoriasis
  • External skin preparation containing povidone iodine and used for treating psoriasis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Example 1: Preparation of samples containing povidone-iodine and polyvinyl butyral and detection of film-forming time

[0029] Sample formulation (Table 1)

[0030] Table 1: Sample formulations containing povidone-iodine and different concentrations of polyvinyl butyral

[0031] sample Povidone iodine polyvinyl butyral castor oil Absolute ethanol sample 1 5g 6g 2g 87g sample 2 5g 8g 2g 85g sample 3 5g 10g 2g 83g

[0032] Sample configuration

[0033] Accurately weigh the prescribed amount of anhydrous ethanol in the container, stir at room temperature, respectively accurately weigh the prescribed amount of polyvinyl butyral, slowly add it to each container, continue to stir until it is completely dissolved, and then accurately weigh Take the povidone-iodine of the prescribed amount, slowly add it to each container, and continue to stir until it is completely dissolved. Finally, accurately weigh the castor oil of the pre...

Embodiment 2

[0039] Example 2: Determination of Film Ductility of Sample 2 in Example 1

[0040] Film-making method: cut the self-adhesive paper containing silicone oil layer with an area of ​​25mm*150mm and place it in a shallow groove mold of 25mm*150mm, then weigh about 1.2g of sample 2, add it dropwise and spread it on the self-adhesive On the paper, dry it with hot air from a hair dryer for about 3 minutes, and slowly tear off the film.

[0041] Testing equipment: tensile testing machine, cutting tools, stopwatch.

[0042] Detection method: Cut out a representative film with a width of (25.0±0.5)mm from the test material, let it relax for at least 300s after removing the material, and make two parallel films with a distance of (100.0±10)mm on the sample Mark, and make the two distances to the two ends equidistant, clamp the sample beyond the mark in the two grips of the tensile testing machine, and elongate the sample by 20% at a tensile speed of (300±10) mm / min. Record the maximum lo...

Embodiment 3

[0047] Embodiment 3: Determination of water vapor transmission rate of sample 2 in embodiment 1.

[0048] Film-making method: Cut the self-adhesive paper containing the silicone oil layer with an area of ​​5*5cm and place it in a shallow groove mold of 5*5cm, then weigh about 1.2g of sample 2, add it dropwise and spread it on the self-adhesive On the paper, dry it with hot air from a hair dryer for about 3 minutes, and slowly tear off the film.

[0049] Testing equipment: five clean drying cylinders (made of corrosion-resistant materials, with a flange at each end, can only hold 20ml of deionized water, electronic balance, hygrometer, drying box, surgical blade.

[0050] Detection method: use the flange of the splint as a template, cut off the sample of the material to be tested, add enough water at room temperature, make the air gap between the liquid surface and the placed sample be (5±1)mm, place the circle Cover the flange of the test container with the shaped sample accu...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a povidone-iodine-containing external skin preparation for treating psoriasis. The povidone-iodine-containing external skin preparation comprises the following components: povidone-iodine, a film-forming agent and a non-aqueous solvent. After the skin preparation is applied to the skin, a smooth and uniform closed film can be rapidly formed, povidone iodine is gradually released, and various infectious microorganisms at the smearing part are killed; meanwhile, the formed closed film can be firmly adhered to the skin, and the effects of isolating the skin from external infection microorganisms, avoiding secondary infection, accelerating wound healing, reducing rash, reducing skin plaques and scales, reducing psoriasis skin and nail damage, blocking water and ventilating can be achieved.

Description

technical field [0001] The invention relates to the field of medicine, in particular to an external skin preparation containing povidone iodine for treating psoriasis. Background technique [0002] Psoriasis is an abnormal immune disease caused by abnormal T cells in a polygenic genetic background. The specific pathogenesis has not yet been fully understood, and studies suggest that it may be the following mechanisms: 1) Cellular immune-mediated; 2) Angiogenesis-related factors; 3) Neuroimmunity; 4) Nuclear factor-KB; 5) Interleukin 10; 6 ) phosphorylase kinase, etc. [0003] According to the "Guidelines for the Diagnosis and Treatment of Psoriasis in China" released in 2018, the prevalence rate of psoriasis in Europe and the United States is 1%-3%, and the prevalence rate in 6 cities surveyed in my country in 2008 is 0.47%. Based on this, the domestic psoriasis patients are estimated The number of people is about 6.5 million. [0004] The severity of psoriasis can be defi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/79A61K9/00A61K47/32A61K47/10A61P17/06A61P17/02
CPCA61P17/02A61K47/32A61K33/18A61K9/7015
Inventor 梁波王炜彭海洲
Owner IVEW THERAPEUTICS (ZHUHAI) CO LTD
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com