Fluorescent compound and application thereof in measuring solution viscosity

A technology of fluorescent compounds and compounds, which is applied in the field of fluorescent compounds, can solve problems such as the quantitative analysis of undisclosed solution viscosity, and achieve the effect of realizing microanalysis and highlighting substantive characteristics

Pending Publication Date: 2022-07-01
CHANGSHU INSTITUTE OF TECHNOLOGY
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, the patent application with the invention publication number CN113845462 discloses a fluorescent probe compound composed of indole and indole iodine salt. To characterize the size of the solution viscosity, but there is no disclosure of the performance of the quantitative analysis of the solution viscosity

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Fluorescent compound and application thereof in measuring solution viscosity
  • Fluorescent compound and application thereof in measuring solution viscosity
  • Fluorescent compound and application thereof in measuring solution viscosity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Synthesis of Organic Small Molecular Fluorescent Compounds Abbreviated as PB-16

[0027] 1) Synthesis of pyridinium salt (compound II)

[0028] Combine 4-methylpyridine (1.1 mL, 10 mmol) and CH 3 (CH 2 ) 15 I (3.52 g, 10 mmol) was dissolved in a toluene solution (20 mL), placed in a flask and stirred for 1 hour. Then, the mixture in the flask was refluxed for 8 hours. After cooling and filtration, the obtained solid was washed three times with absolute ethanol, and the obtained white solid after drying was compound II. And compound Ⅱ was characterized by hydrogen spectrum, the results are as follows:

[0029] 1 H NMR (400 MHz, DMSO- d 6 ) δ (ppm): 8.92 (d, J = 6.40 Hz, 2H), 7.98 (d, J = 6.42 Hz, 2H), 4.51 (t, J = 7.43 Hz, 2H), 2.61 (s, 3H), 1.23 (s, 28H), 0.85 (t, J = 6.85 Hz, 3H).

[0030] The hydrogen spectrum of compound II is shown as figure 1 shown.

[0031] 2) Synthesis of fluorescent compound PB-16

[0032] Compound 2 (0.331 g, 1 mmol) and compoun...

Embodiment 2

[0037] Test Experiment of Photophysical Properties of PB-16 in Different Solvents

[0038] The test solutions containing 10 μM PB-16 were prepared with different kinds of organic solvents, and the absorption spectra and fluorescence emission spectra of the above solutions were tested by ultraviolet spectrophotometer and fluorescence spectrometer. see the results Figure 5 .

[0039] from figure 1 It can be seen that the absorbance and fluorescence intensity of the organic small molecule fluorescent compound in pure glycerol are larger, and the absorbance and fluorescence intensity in other low viscosity solvents are smaller, which indicates that the organic small molecule fluorescent compound is sensitive to viscosity.

Embodiment 3

[0041] Viscosity Response Test Experiment of PB-16

[0042] put H 2 O and glycerol were mixed in different proportions to prepare mixed solvents with different viscosity values, and then PB-16 was added to prepare a test solution containing 10 μM PB-16. The above solution was tested with a fluorescence spectrometer for its fluorescence emission spectrum, and its fluorescence spectrum was fitted to obtain a corresponding curve.

[0043] exist Image 6 In (A), with the increase of the proportion of glycerol, the fluorescence intensity of the organic small molecule fluorescent compound gradually increases, indicating that the organic small molecule fluorescent compound responds obviously to the change of viscosity. from Image 6 In (B), it can be seen that the fluorescence intensity of the organic small molecule fluorescent compound PB-16 I F and viscosity η fit the Förster–Hoffmann equation, and the equation log obtained by fitting I F =1.26 +0.38logη. Therefore, the vis...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides a fluorescent compound and application thereof in measuring solution viscosity, the chemical structural formula of the fluorescent compound is shown in the specification, and R is methane group or ethyl group. The fluorescent compound provided by the invention can be applied to the determination of the viscosity of a solution, and has the advantage of micro determination.

Description

technical field [0001] The invention relates to the field of fluorescent compounds, in particular to a viscosity-responsive fluorescent compound and its application in measuring solution viscosity. Background technique [0002] Viscosity is the ability of a fluid to resist deformation. It is a physical quantity that indicates the internal friction of the fluid when it flows. It is an important indicator used to identify the quality of some finished or semi-finished products. At present, the main method for detecting viscosity is viscometer method, and the measuring instruments include falling ball viscometer, rotational viscometer, etc. These methods of detecting viscosity require the direct contact between the viscometer and the solution to be measured. The viscometer may not be reused after being contacted. Therefore, there is a need for a method for measuring the viscosity of the liquid without contacting the solution with the measuring instrument and requiring a small am...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C07D401/06C09K11/06G01N21/64
CPCC07D401/06C09K11/06G01N21/643C09K2211/1029
Inventor 魏蒙蒙杨锐张惠国刘玉申钱斌韩志达况亚伟
Owner CHANGSHU INSTITUTE OF TECHNOLOGY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap