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Intravascular stent system and preparation method thereof

A vascular stent and transportation system technology, applied in the field of vascular stent system and its preparation, can solve the problems of vascular restenosis, vascular wall damage, etc., and achieve the effect of reducing the feeling of intervention, low delivery resistance, and good support strength

Pending Publication Date: 2022-07-29
SHANGHAI BIO HEART BIOLOGICAL TECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the existing vascular stents are made of medical stainless steel. With the gradual repair of vascular function, the vascular stent made of medical stainless steel will remain inside the blood vessel for a long time, which is likely to cause vascular restenosis, damage to the vascular wall, and a series of complications.

Method used

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  • Intravascular stent system and preparation method thereof
  • Intravascular stent system and preparation method thereof
  • Intravascular stent system and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] like figure 1 As shown, a vascular stent system includes a stent and a balloon delivery system for transporting the stent to the lesion. The balloon delivery system includes a balloon 2. By changing the state of contraction and expansion of the balloon 2, the The stent is delivered to the lesion and disengaged from the stent. The stent includes a stent base 4 and a drug coating disposed on the stent base 4. In this embodiment, the material of the stent base is a biodegradable material, specifically polylactic acid. In this embodiment, the in vivo degradation time of the stent matrix 4 is 24-48 months, and the degradation time will vary depending on the physical condition of the patient. The melt flow index of the polylactic acid described in this example is 42045g / 10min, and the test conditions for the melt flow index are: GB / T3682-2000 190°C / 2.16Kg. The tensile strength of the polylactic acid is greater than or equal to 50MPa, and the test reference standard for the ...

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Abstract

The invention provides a degradable intravascular stent system which comprises a stent, the stent comprises a stent base body and a drug coating arranged on the stent base body, and the stent base body is made of a biodegradable material; the balloon conveying system conveys the stent to a lesion site, the balloon conveying system comprises a balloon, and the state of connection or disconnection between the balloon and the stent base body can be achieved by changing the state of the balloon and the stent base body. According to the technical scheme, the stent in the intravascular stent system is made of the degradable material and carries the medicine layer, the radial expansion supporting effect on the blood vessel can be achieved, medicine can be released for a long time, the effect of long-term treatment on an injured part is achieved, the stent is gradually degraded along with gradual repairing and perfecting of the blood vessel, and the treatment effect is good. Carbon dioxide and water which can be absorbed by a human body are generated, the stent is prevented from being retained in the human body for a long time, and secondary injuries such as vascular restenosis or complications are avoided.

Description

technical field [0001] The invention belongs to the technical field of medical devices, and in particular relates to a blood vessel stent system and a preparation method thereof. Background technique [0002] Vascular stent refers to the purpose of placing an inner stent in the diseased segment on the basis of the expansion of the lumen balloon to support the narrowed and occluded blood vessels, reduce the elastic retraction and remodeling of the blood vessels, and maintain the smooth blood flow in the lumen. Some stents also have the effect of preventing restenosis. Most of the existing vascular stents are made of medical stainless steel. With the gradual restoration of vascular function, the vascular stent made of medical stainless steel will remain in the blood vessel for a long time, which is likely to cause vascular restenosis, damage to the vascular wall and cause a series of complications. Especially when using vascular stents for under-knee treatment, due to the spe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/90A61L31/06A61L31/08A61L31/10A61L31/14A61L31/16A61L31/18A61M31/00A61F2/958
CPCA61F2/90A61M31/002A61L31/06A61L31/08A61L31/16A61L31/14A61L31/18A61L31/10A61F2002/9583A61L2300/602A61L2300/606A61L2300/406C08L67/04C08L39/06C08L77/00C08L87/005
Inventor 汪立蔡涛王君毅张晨朝
Owner SHANGHAI BIO HEART BIOLOGICAL TECHNOLOGY CO LTD
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