Unlock instant, AI-driven research and patent intelligence for your innovation.

Method for modifying and preparing humulus lupulus

A technology of modifying hops, applied in the field of health care products and food, to achieve the effect of mild reaction conditions, easy industrial production, and simple process

Pending Publication Date: 2022-08-02
DALI UNIV
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] There is no publication of the same document as the technical solution of the present invention

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] (1) Disperse 100g of hops dry powder and 0.5g of cellulase in 500g of ethanol, ultrasonically disperse, and then keep the water bath at 50°C for 3h;

[0024] (2) Mix 0.1 g of cannabidiol, 0.05 g of polyethylene glycol, and 100 g of pure water, sonicate to disperse evenly, add the dispersion dropwise to the mixture in step (1), stir to mix evenly, and use sodium carbonate Adjust the pH of the mixture to 7;

[0025] (3) The mixture of step (2) is ultrasonically mixed at normal pressure in an ultrasonic mixer for 30min;

[0026] (4) Transfer the mixture in step (3) to a multi-effect external circulation evaporator, control the temperature at 60°C, and concentrate and dry under reduced pressure to obtain hops containing active cannabidiol.

[0027] The active cannabidiol hops prepared in this example were eluted isocratically with a chromatographic column: InertSustain C18 and methanol-water (volume ratio 85:15) as the mobile phase; under this chromatographic condition, ta...

Embodiment 2

[0029] (1) Disperse 200g of hops dry powder and 2g of cellulase in 500g of ethanol, ultrasonically disperse, and then keep the water bath at 60°C for 2h;

[0030] (2) Mix 2g of cannabidiol, 0.16g of polysorbate-80 and 200g of pure water, sonicate until dispersed evenly, add the dispersion dropwise to the mixture in step (1), stir to mix evenly, use hydrogen carbonate Sodium adjusts the pH of the mixture to 8;

[0031] (3) The mixture of step (2) is ultrasonically mixed at normal pressure in an ultrasonic mixer for 60min;

[0032] (4) Transfer the mixture in step (3) to a multi-effect external circulation evaporator, control the temperature at 50°C, and concentrate and dry under reduced pressure to obtain hops containing active cannabidiol.

[0033] The active cannabidiol hops prepared in this example were eluted isocratically with a chromatographic column: InertSustain C18 and methanol-water (85:15) as the mobile phase; The hop samples of active cannabidiol were injected and...

Embodiment 3

[0035] (1) Disperse 300g of hops dry powder and 6g of cellulase in 500g of ethanol, ultrasonically disperse, and then keep the water bath at 55°C for 2h;

[0036] (2) Mix 1.5 g of cannabidiol, 3 g of sodium dodecyl benzene sulfonate, and 300 g of pure water, sonicate until uniformly dispersed, drop the dispersion into the mixture in step (1), stir to mix uniformly, Adjust the pH of the mixture to 7 with sodium hydroxide;

[0037] (3) The mixture of step (2) is ultrasonically mixed at normal pressure in an ultrasonic mixer for 40min;

[0038] (4) Transfer the mixture in step (3) to a multi-effect external circulation evaporator, control the temperature at 60°C, and concentrate and dry under reduced pressure to obtain hops containing active cannabidiol.

[0039] The active cannabidiol hops prepared in this example were eluted isocratically with a chromatographic column: InertSustain C18 and methanol-water (85:15) as the mobile phase. Under this chromatographic condition, the C...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a method for modifying and preparing humulus lupulus, which comprises the following steps: carrying out ultrasonic dissolution on dried humulus lupulus powder, cellulase and ethanol by adopting a chelating method, keeping the temperature at 50-60 DEG C for 1-4 hours, carrying out ultrasonic dissolution on cannabidiol, a surfactant and pure water, adding into the solution, carrying out normal-pressure ultrasonic mixing in an ultrasonic mixer, and concentrating and drying under reduced pressure, thereby obtaining the humulus lupulus. The humulus lupulus containing the active cannabidiol is obtained; according to the method disclosed by the invention, active factors of the humulus lupulus are effectively improved, and a cannabidiol modifying substance is introduced, so that the modified humulus lupulus has the effects of resisting bacteria, diminishing inflammation, resisting pressure and the like, has a relatively good development prospect and is easy to realize industrial production.

Description

technical field [0001] The invention belongs to the field of food and health care products, and in particular relates to a method for preparing modified hops containing active cannabidiol. Background technique [0002] Hops are known as "the soul of beer" and become one of the indispensable raw materials in brewing beer. Hops not only act as a natural preservative in beer, but also impart its unique bitterness and aroma characteristics to beer. The quality or modification of hops will directly affect the quality of beer, among which resin components, volatile oils and polyphenols will affect the taste and flavor of beer. Hops itself has strong medicinal value: antibacterial effect, α-acid and β acid in hops have good antibacterial effect; antioxidant effect, α-acid and its hydrogenation products, β-acid and polyphenol in hops All kinds of substances have antioxidant effect; anti-tumor effect, resinous components in hops can inhibit human gastric adenocarcinoma cell CRL-179...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/10A23L33/105
CPCA23L33/10A23L33/105A23V2002/00A23V2200/30A23V2200/06A23V2250/21A23V2300/10A23V2300/48
Inventor 苏云鹏杨冠英张筱岚赵媛张颖
Owner DALI UNIV