Method for producing transgene paddy with amount of spikelet being increased
A technology of transgenic rice and genes, applied in the field of genetic engineering, can solve the problem of not getting it
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Embodiment 1
[0073] Isolation of OsCen1 and OsCen2 Genes in Rice CENTRORADIALIS(CEN)-like
[0074] Using the conservative fragment of the fourth exon of the CEN gene of Snapdragon as a probe, the rice (Guangluai 4, Indica) genomic DNA library was screened by in situ hybridization. After three rounds of screening, six positive clones were obtained. Two positive clones with the strongest signals, FD229 and FD322, were selected for physical map construction and subcloning, and sequencing was completed. Two CEN-like genes OsCen1 (also called FDR1) and OsCen2 (also called FDR2) were obtained.
[0075] According to the genome sequence of OsCen1 and OsCen2, specific primers were designed, and the reverse transcription product of the mRNA in the rice inflorescence meristem was used as the template, and the corresponding OsCen1 and OsCen2 genes were isolated by 5'RACE and 3'RACE methods. CDNA, and completed sequencing. OsCen1 cDNA is 907bp long, and OsCen2cDNA is 956bp long. Comparing cDNA and genomic ...
Embodiment 2
[0078] Obtain the complete ORF of OsCen1 and OsCen2
[0079] (A) Obtain the complete ORF of OsCen1
[0080] For transgenic needs, a complete ORF must be obtained, so the 5′ primer is designed before the start codon of the OsCen1 gene, namely OsCen1-ORF-5′:
[0081] ttacctgtccctccaaggc (SEQ ID NO: 3)
[0082] And design a 3′ primer after the stop codon, namely OsCen1-ORF-3′:
[0083] cacaatctag tgatgtggc (SEQ ID NO: 4)
[0084] And using the reverse transcription product of the mRNA in the rice inflorescence meristem as a template, the ORF of OsCen1 plus a 3′UTR region was amplified by conventional RT-PCR, and the total length was 643bp, which was cloned into the pGEM-T vector , The number of the positive clone is pCSL0034.
[0085] The amplified 643bp cDNA of OsCen1 is shown in Figure 1 and SEQ ID NO:1. The amino acid sequence of the encoded OsCen1 protein is shown in SEQ ID NO:2.
[0086] (A) Obtain the complete ORF of OsCen2
[0087] Design a 5′ primer before the start codon of ...
Embodiment 3
[0094] Construction of sense expression vector for OsCen1 and OsCen2
[0095] (A) Construction of OsCen1 sense expression vector
[0096] After digestion with SpeI, fill in, then digest with NcoI to cut the 643bp cDNA of OsCen1 in pCSL0034 plasmid, and connect it to the intermediate vector pJIT163 (available from the British JOIN INNES Research Center), and then add Two 35S strong promoters plus the forward OsCen1 cDNA gene and the fragment of CaMV polyA were cloned into the plant expression vector pCAMBIA1301 (available from the CAMBIA Research Center) to obtain the sense expression vector of OsCen1, named pCSL0040, this vector The total length is 14000bp, the resistance in E. coli is kanamycin resistance, and the resistance in plants is hygromycin resistance. The vector also carries the GUS gene in the T-DNA region. The plasmid map of pCSL0040 is shown in Figure 3.
[0097] (B) Construction of OsCen2 sense expression vector
[0098] The construction process of OsCen2 sense expre...
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