Sustained releasing huperzine preparation
A slow-release preparation, huperzine A technology, applied in the direction of pill delivery, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the impact of drug efficacy, patients can not remember the time of taking the medicine, and it is difficult to It is difficult to grasp the time and frequency of taking medicine to achieve the effect of feasible and reliable drug treatment
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Embodiment 1
[0013] Example 1: Huperzine water-soluble matrix sustained-release tablet with a single tablet weight of 300 mg.
[0014] Component weight percentage: drug Huperzine A 0.1-0.4, speed control part uses hydroxypropyl methylcellulose 15, excipients use micronized silica gel 0.5, magnesium stearate 0.5, microcrystalline cellulose 30.0 and lactose 53.9- 53.6, a total of 100.0%.
[0015] The specific steps are as follows: Weigh each component according to the above prescription. Take Huperzine A, mix with microcrystalline cellulose for 10 minutes, add hydroxypropyl methylcellulose, lactose and micronized silica gel for another 10 minutes, add magnesium stearate and mix for 5 minutes. Transfer the mixed pellets to the feed hopper of the tablet machine, and adjust the tablet weight regulator to make the tablet weight about 300 mg. Take 500 grams of the tablet, transfer it to a small coating machine, and coat it with a 10% coating powder solution, and stop when the tablet weight increases ...
Embodiment 2
[0016] Example 2: Huperzine B matrix sustained-release tablet with a single tablet weight of 300 mg.
[0017] Component weight percentage: drug Huperzine B 0.1-0.4, 0.25 can be used, hydroxypropyl methylcellulose 20 is used for the speed control part, micronized silica gel 0.5, magnesium stearate 0.5, and microcrystalline cellulose 30.0 are used as excipients And lactose 51.1%-50.8, a total of 100.0%.
[0018] The specific steps are as "Example 1"
Embodiment 3
[0019] Example 3: Melaleuca tower extract matrix sustained-release tablet with a single tablet weight of 300 mg.
[0020] Component weight percentage: Melaleuca extract (Huperzia serrata) 1-4, 2.5 can be selected, hydroxypropyl cellulose 20.0 is used for the speed control part, micronized silica gel 0.5, magnesium stearate 0.5, lactose 70 -75, a total of 100.0%.
[0021] The specific steps are as "Example 1"
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