High-flux filter method of composite polyphase catalysis materials

Abstract

A high-throughput screening method for combined heterogeneous catalytic materials, in which each reaction tube in a parallel combined heterogeneous catalytic reactor is connected to a multi-valve mass spectrometry detection system through a capillary tube. The multi-channel reaction gas generated in the reaction furnace enters the multi-way valve of the mass spectrometry detection system through the capillary, and any part of the gas is selected by the multi-way valve to enter the mass spectrometer detector for analysis. Any one of the capillary tubes is connected to any one of the multi-way valves through a six-way valve, and the six-way valve is connected to a gas chromatograph at the same time. Switch the six-way valve to control the gas in the capillary to enter the gas chromatograph or enter the multi-way valve through the quantitative tube; when the reaction gas in the capillary enters the gas chromatograph and the multi-way valve, a chromatographic result and a mass spectrometry result are obtained , using the coefficient relationship between the two sets of values ​​to correct the mass spectrometry results of all gases to obtain the selectivity of each product in the reaction gas. The calculation of the reaction conversion rate is realized by comparing the mass spectrometry data of each reaction gas with the blank reaction tube.

Description

technical field [0001] The invention relates to a combined method for rapidly screening heterogeneous catalysts. Background technique [0002] Combinatorial chemistry is a new method for the rapid synthesis of a large number of compounds developed in the past 20 years. Combinatorial chemical synthesis technology has brought revolutionary changes to traditional organic synthetic chemistry, and is another revolution in the history of organic synthesis, so it is called one of the important scientific achievements in recent years. [0003] Attempts at combinatorial methods are not new. In 1963, Merrifield reported solid-phase peptide synthesis, which earned him the Nobel Prize in Chemistry in 1984. In the 1980s, with the introduction of the concept of hybrid splitting by Furka and the optimization of the coding scheme for solid-phase synthesis by Geysen and Houghten, the concept of combination was greatly developed. These early works laid the groundwork for today's successful ...

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Problems solved by technology

[0013] Although the above HTS technology has solved the screening of the heterogeneous catalyst sample library to a certain extent, the methods are not perfect, and the operating conditions of all reactions are very different from the reaction conditions on the traditional single-tube reactor. Makes it difficult to compare combined screening results with traditional screening results

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