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Method for enzyme hydrolyzing zein through two steps method

A zein and method enzyme technology, which is applied in the technical field of zein hydrolysis, can solve the problems of ineffective production of corn depressor peptide, insoluble prolamin components, prolaminase inability to hydrolyze prolamin, etc. Achieve high social and economic benefits, increase added value, and high hydrolysis efficiency

Inactive Publication Date: 2006-11-22
SOUTH CHINA UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main defect of this method is that the prolamin components in zein cannot be dissolved in water, protease cannot hydrolyze prolamin, and the main components of zein depressant peptide are all derived from zein
Therefore, this method is not an effective method for producing corn antihypertensive peptide

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] 1 Weigh 3 grams of zein and fully dissolve it with 150mL 65% ethanol solution to make a 2% protein ethanol solution, and adjust the pH value to 8.0 with 0.2mol / L NaOH solution;

[0029] 2 Prepare an alkaline protease with disodium hydrogen phosphate-sodium dihydrogen phosphate buffer solution with a pH value of 8.0 to prepare 1% enzyme solution (enzyme activity unit is 1800U / mL);

[0030] 3 The first enzymatic hydrolysis: Measure 150mL of protein solution, add 6mL of 1% protease solution, mix well, enzymolyze in a water bath at 48°C, add 0.1mol / L NaOH solution dropwise, and keep the pH value of the solution at 8.0;

[0031] 4 After 20 minutes of enzymatic hydrolysis, the reaction solution was quickly distilled under reduced pressure at 50°C, and stopped after distilling out 35mL of ethanol solution;

[0032] 5 Add deionized water to the above concentrated solution to 150mL, adjust the pH to 8.0 with 0.1mol / L NaOH solution, then add 14mL 1% protease solution for hydrolys...

Embodiment 2

[0035] 1 Weigh 7.5 grams of zein and fully dissolve it with 150mL 75% ethanol solution to make a 5% protein ethanol solution, and adjust the pH value to 8.0 with 0.25mol / L KOH solution;

[0036] 2 Prepare an alkaline protease with disodium hydrogen phosphate-sodium dihydrogen phosphate buffer solution with a pH value of 8.0 to prepare 1% enzyme solution (enzyme activity unit is 1800U / mL);

[0037] 3 The first enzymatic hydrolysis: Measure 150mL of protein solution, add 25mL of 1% protease solution, mix well, enzymolyze in a water bath at 55°C, add 0.1mol / L NaOH solution dropwise, and keep the pH value of the solution at 8.0;

[0038] 4 After 20 minutes of enzymatic hydrolysis reaction, the reaction solution was quickly distilled under reduced pressure at 50°C, and stopped after distilling out 65mL of ethanol solution;

[0039] 5 Add deionized water to the above concentrated solution to 150mL, adjust the pH to 8.0 with 0.25mol / L KOH solution, then add 25mL of 1% protease soluti...

Embodiment 3

[0042] 1 Weigh 4.5 grams of zein and fully dissolve it with 150mL 70% isoalcohol solution to make a 3% protein ethanol solution, and adjust the pH value to 8.0 with 0.5mol / L NaOH solution;

[0043] 2 Prepare an alkaline protease with disodium hydrogen phosphate-sodium dihydrogen phosphate buffer solution with a pH value of 8.0 to prepare 1% enzyme solution (enzyme activity unit is 1800U / mL);

[0044] 3 The first enzymatic hydrolysis: Measure 150mL of protein solution, add 18mL of 1% protease solution, mix well, enzymolyze in a water bath at 60°C, add 0.1mol / L NaOH or KOH solution dropwise to keep the pH of the solution at 8.0;

[0045] 4 After 20 minutes of enzymatic hydrolysis, the reaction solution was quickly distilled under reduced pressure at 50°C, and stopped after distilling out 55mL of ethanol solution;

[0046] 5 Add deionized water to the above concentrated solution to 150mL, adjust the pH to 8.0 with 0.5mol / L NaOH solution, then add 18mL of 1% protease solution for...

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PUM

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Abstract

A two-step method for enzymolyzing the corn gliadin to obtain the hydrolyzed product used for health-care food to lower blood pressure includes such steps as proportionally adding proteinase to the solution of corn gliadin, hydrolyzing evaporating part of organic solvent (ethanol or propanol), adding deionized water, regulating pH=8, proportionally adding proteinase, hydrolyzing again, vacuum concentrating and freeze drying.

Description

technical field [0001] The invention relates to the technological field of zein hydrolysis, in particular to a production process of two-step enzymatic hydrolysis of zein in an organic phase and an aqueous phase. Background technique [0002] Zein is a high value-added product extracted from corn raw material or corn gluten meal, a by-product of the corn starch production process. Since zein is insoluble in water, it has no food value. If it can be hydrolyzed, its water solubility can be increased and its functional properties can be improved, and it may be widely used in food production. [0003] According to some recent research reports, a small peptide can be obtained after hydrolysis of zein, which is currently used in antihypertensive peptide products made of biological protein materials, and has inhibitory activity on ACE (angiotensin converting enzyme) The strongest kind of inhibitor. This discovery doubles the value of zein hydrolyzate...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12P21/00A23L1/305C07K1/00A23J1/12A23J3/14A23L33/18
Inventor 黄国平温其标杨晓泉
Owner SOUTH CHINA UNIV OF TECH