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Blood-fat regulating medicinal composition and use thereof

A composition and a technology for regulating blood lipids, which can be used in drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc.

Inactive Publication Date: 2007-08-01
HANGZHOU XINFU TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] So far, there is no similar composition drug on the market

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Example 1 tablet

[0021] (1) Ingredients

[0022] Soy Isoflavones

4 tablets (1400mg)

Ginkgo biloba total flavonoids

1400mg in 4 tablets)

Simvastatin

20mg

20mg

pantethine

500mg

500mg

Soy Isoflavones

225mg

-

Ginkgo flavonoids

-

225mg

Crystalline Cellulose

120mg

120mg

Magnesium aluminate metasilicate

-

-

Sucrose Fatty Acid Ester

140mg

140mg

Hydroxypropyl Cellulose

48mg

48mg

Magnesium stearate

24mg

24mg

Crospovidone

48mg

48mg

lactose

Appropriate amount

Appropriate amount

[0023] (2) Method

[0024] Measure the above-mentioned ingredients according to the amount of each of the above-mentioned ingredients, and prepare tablets according to the item "Granules" of the General Provisions of Preparations in the Chinese Pharmacopoeia.

Embodiment 2

[0025] Example 2 Granules

[0026] (1) Ingredients

[0027] Soy Isoflavones

[0028] Polysorbate 80

[0029] (2) Preparation method: Measure the above-mentioned ingredients according to the amount of each of the above-mentioned ingredients, and prepare granules according to the item "Granules" in the general provisions of the Chinese Pharmacopoeia.

Embodiment 3

[0030] Example 3 Capsules

[0031] (1) Ingredients

[0032] Soy Isoflavones

[0033] (2) Preparation method: Measure the above-mentioned ingredients according to the amount of each of the above-mentioned ingredients, and prepare capsules according to the item "Capsules" of the general provisions of the Chinese Pharmacopoeia.

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PUM

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Abstract

A composite medicine for regulating blood fat and treating hyperlipemia is prepared from simavastatin, pantethine, flavone, and pharmacologically acceptable additives. It can also be used to prepare the medicine for decreasing the content of cholesterol in blood.

Description

technical field [0001] The invention relates to a blood lipid improving agent composition, in particular to a composition containing simvastatin, pantethine and flavonoids, and is used in the preparation of blood lipid-regulating medicines such as improving blood cholesterol content. Background technique [0002] Hyperlipidemia characterized by elevated low-density lipoprotein and very low-density lipoprotein can cause atherosclerotic endothelial cell dysfunction, hyperplatelet aggregation, foam cell formation, etc., and is a major risk factor for premature coronary heart disease in humans One, so the blood lipid improving agent has a broad market prospect. [0003] Simvastatin is a fully synthetic novel hydroxymethylglutaryl-CoA reductase inhibitor. It is one of the most effective lipid-lowering drugs at present. This product is well absorbed after oral administration. After absorption, the concentration in the liver is higher than that in other tissues. After extensive f...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/366A61P3/06A61K31/352
Inventor 过鑫富楼宜嘉
Owner HANGZHOU XINFU TECH CO LTD