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Matrine vaginal gel

A technology of vaginal gel and matrine, which is applied in drug delivery, organic active ingredients, diseases, etc., can solve the problems of difficult drug release, easy damage to vaginal efficacy, and short drug action time, so as to achieve convenient administration, Good vaginal retention and long drug action time

Inactive Publication Date: 2003-04-16
盛俊泰 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most of the medicines widely used clinically to treat this disease are external suppositories, i.e. vaginal suppositories and vaginal effervescent suppositories, which have inconvenience in administration, poor retention in the vagina, short drug action time, and difficulty in taking all the medicines. Disadvantages of release, foreign body sensation in the vagina, easy to damage the vagina, and not very obvious curative effect
And the suppository is easy to contaminate the clothes after use

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Take: Matrine 50Kg Carbomer 50Kg

[0030] Glycerin 500Kg Distilled water 4500Kg The above formula is prepared according to the known technology and then put into the vaginal applicator and sealed.

Embodiment 2

[0032] Take: Matrine 5Kg Carbomer 5Kg

[0033] Glycerin 25Kg Distilled water 400Kg The above formula is prepared according to the known technology and then put into the vaginal applicator and sealed.

Embodiment 3

[0035] Take: Matrine 20Kg Carbomer 20Kg

[0036] Glycerin 200Kg Distilled water 2000Kg The above formula is prepared according to known technology and then put into the vaginal applicator and sealed. Example 4

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PUM

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Abstract

A matrine vagina gel is prepared from matrine (5-50 wt. portions) Kapomu (5-50), glycerine (25-500) and distilled water (400-4500). Its advantages are high curative effect, long stay time, no damage to vagina and no pollution to clothes.

Description

technical field [0001] The invention relates to the technical field of gynecological medicine. Background technique [0002] Matrine (Matrine) is a monomeric alkaloid isolated from the traditional Chinese medicine Sophora flavescens. It can improve immunity, increase white blood cell count, strengthen the body's immunity, play a significant role in antibacterial and anti-inflammatory, and has antiviral, anti-inflammatory, anti- Various pharmacological activities such as tumor and liver function protection. Because matrine has good anti-infection effects on dysentery liver bacteria, skin fungi, trichomonas, amoeba, etc., it is mostly used in the treatment of chronic cervicitis, cervical erosion, trichomonas and fungal vaginitis, senile Vaginitis, adnexitis, genital itching, genital eczema and other diseases. [0003] Cervicitis is a common disease in women of childbearing age. The pathogens are mainly Staphylococcus, Streptococcus, Escherichia coli and anaerobic bacteria, f...

Claims

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Application Information

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IPC IPC(8): A61K9/00A61K31/4375A61P15/02A61P31/00A61P33/02
Inventor 盛俊泰张瑞琛
Owner 盛俊泰
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