Glycosides compound monomer in Chinese herbaceous peony, and method for extracting and separating same

Abstract

A paeoniflorin monomer as a novel medicine is prepared from white (or red) peony through swelling in aqueous solution of alcohol, thermal reflux, concentrating, ultrasonic extracting in acetone solution, concentrating, mixing with gum powder, concentrating, vacuum chromatography, eluting, concentrating, separating by silica gel column, eluting and distribution chromatography. Its advantages are simple process, low cost and high yield.

Description

Technical field

[0001] The invention relates to the field of biomedicine, in particular to a glycoside compound monomer in paeoniflora, and a method for extraction and separation thereof. The monomers of glycoside compounds in paeoniflorin include paeoniflorin monomer, albiflorin monomer, benzoylpaeoniflorin monomer and oxypaeoniflorin monomer, wherein paeoniflorin The monomer content is above 90%, which meets the purity requirements of a new class of plant drugs. Background technique

[0002] White peony root or red peony root is a commonly used traditional Chinese medicine. It has been clinically used for thousands of years. It is listed as a medium product in the "Shen Nong's Materia Medica". It has the effects of calming the liver and relieving pain, nourishing blood and regulating menstruation, restraining yin and antiperspiration. Effective, the main treatment of headache, dizziness, hypochondriac pain, abdominal pain, limb contracture pain, blood deficiency and yellow, irr...

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