Polyurethane material containing fluorin in its lateral chain and preparing method thereof

Abstract

A polyurethane material containing F in side chain is prepared through alternative polymerization between the flexible chain segment consisting of polyether diol and / or polycarbonate diol and the rigid chain segment consisting of diisocyanate and chain-enlarging agent. Its advantages are high biologic stability and compatibility and high elasticity, strength and resistance to oxidizing and hydrolysis. It can be used for preparing artificial blood vessel, heart valve, etc.

Description

1. Technical Field

[0001] The invention belongs to the technical field of polymer biomedical materials and their preparation, and is a side chain fluorine-containing polyurethane thermoplastic elastomer material and a preparation method thereof. 2. Background technology

[0002] In the field of materials implanted in the body and in contact with blood, polyurethane has been widely used because of its high strength, high elasticity, good biocompatibility and processability, such as the insulated wire for the lead of cardiac pacemakers. , Artificial blood vessels and various medical catheters, but there are still some problems, such as thrombus formation on the surface of the polyurethane material when it comes into contact with blood, which cannot be used to make artificial small blood vessels, and polyester polyurethane is easy to hydrolyze due to the presence of ester bonds. After hydrolysis, fatty acids will be released to produce catalytic degradation [see L. Pinchuk, Journal ...