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Granule for embedding chemical substance, its production method and equipment

A technology for granules and hydrogenated vegetable oil, applied in a method and a device for implementing the method, in the field of granules for embedding physiologically active substances, can solve the problems of low yield, inability to industrialize production, etc. The effect of adding added value

Inactive Publication Date: 2004-02-25
ALARVITA BIOLIFE CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This technology usually does not use fatty acids as carriers, and the yield is very low, so it cannot be mass-produced industrially

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Embodiment 1

[0047] Formula: stearic acid (18 acid) 75%, fish protein (fish protein) 20%, chitosan (chitosan) 5%.

[0048] Conditions: hose diameter 7.9mm, flow rate 25 liters / hour, nozzle diameter 1.6mm.

[0049] Steps: Stir the stearic acid, fish protein and chitosan at a temperature of 70±3℃, then use a peristaltic pump to transfer the mixture and pour it into an aqueous solution with a temperature of 49±1℃ for granulation .

[0050] Results: The particle size range is 0.5±0.2mm, and the particles are all spherical. And the specific gravity of the particles is heavier than water, the melting point is 55°C, and the output is 25 kg per hour.

[0051] Effect: The particles produced can effectively isolate the fishy smell of fish protein and prevent the damage of air and water to fish protein. Such as rancidity and deliquescence; it also changes the appearance of the product and increases the added value of the product. Example 2

Embodiment 2

[0052] Formula: Stearic acid (18 acid) 63%, lauric acid (12 acid) 32.0%, lactic acid bacteria 5%.

[0053] Conditions: hose diameter 7.9 mm, flow rate 38 liters / hour, nozzle diameter 2.7 mm.

[0054] Steps: Stir stearic acid, lauric acid and lactic acid bacteria in a temperature environment of 55±3℃, then transfer the mixture by peristaltic pump, and pour it into an aqueous solution of 38±1℃ for granulation, and then pick up the particles Store at 4°C.

[0055] Results: The particle size range is 1.0±0.2mm, and the particles are all spherical. The specific gravity of the particles is less than that of water, the melting point is 43°C, and the output is 38 kg per hour.

[0056] Effect: The particles produced can effectively isolate the damage of air and water to lactic acid bacteria, and have the effect of passing gastric acid. It also changes the appearance of the product and increases the added value of the product. Example 3

Embodiment 3

[0057] Formula: Refined hydrogenated hard palm oil (41% stearic acid, 57% palmitic acid, and 2% myristic acid) 90-55%, Beer yeast+Spirulina extract 5%-40%, Chitosan 5%.

[0058] Conditions: hose diameter 7.9mm, flow rate 44.8 liters / hour, nozzle diameter 1.8mm.

[0059] Steps: In a temperature environment of 70±3°C, stir the refined hydrogenated hard palm oil, brewer’s yeast plus spirulina extract and chitosan thoroughly, and then use a peristaltic pump to transfer the mixture, and inject 44.3±1°C Granulate in the aqueous solution, and then pick up the granules and put them in a 40℃ cold air environment for drying.

[0060] Results: The particle size range is 0.5±0.2mm, and the particles are all spherical. The specific gravity of the particles is greater than that of water, the melting point is 55°C, and the output is 45 kg per hour.

[0061] Effect: The particles produced can effectively isolate the taste of brewer's yeast plus spirulina extract, and prevent air and water from ha...

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Abstract

The present invention relates to a granule capable of embedding physiological active substance, including an embedded substance. Its weight percentage is about 0.1-70%, and a base material whose weight percentage is about 30-99.9%, and said base material is one or several kinds selected from hydrogenated vegetable oil, hydrogenated animal oil and / or C8-64 saturated fatty acid and its derivative.Besides. It also provides the method for preparing granule and equipment for implementing method.

Description

Technical field [0001] The invention relates to a particle embedded with a chemical substance, in particular to a particle embedded with a physiologically active substance. The present invention also relates to a method of manufacturing such particles and a device for implementing the method. Background technique [0002] Nowadays, the technology of producing particles in oils and fats is mainly divided into two categories: one is particle generation by coacervation, and the other is particle generation by spray suspension fluidized bed. The accumulation effect is to make different two phases (such as the oil phase and the water phase) produce new composition phases through the effects of high-speed stirring, shaking and emulsification. US Patent No. 6,153,657 discloses an oil-in-water (O / W) emulsified product. The manufacturing process includes: (a) combining an oily substance, a surfactant with a high molecular weight, and a surfactant with a low molecula...

Claims

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Application Information

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IPC IPC(8): A61K9/50B01J13/02
Inventor 邹德纯龚瑞林张克亮李幸懋
Owner ALARVITA BIOLIFE CORP
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