16 results about "Hexacosenoic acid" patented technology

The invention belongs to the technical field of pest control, discloses a bactrocera dorsalis attractant and application thereof, and particularly discloses application of trans-3-hexenoic acid or pharmaceutically acceptable salt thereof in pest control or preparation of a pest attractant. The invention provides the application of the trans-3-hexenoic acid or the pharmaceutically acceptable salt thereof in pest control or preparation of the pest attractant for the first time, and experiments prove that the trans-3-hexenoic acid has a relatively good attraction effect on bactrocera dorsalis and presents a certain degree of dose dependence.

The invention discloses a synthesis method of piperonone, and relates to the technical field of flavors, fragrances and chemical engineering, and the synthesis method comprises the following steps: taking acrylate as a raw material, and carrying out Michael addition reaction with isobutene under the action of Lewis acid to obtain 5-methyl-5-hexenoic acid ethyl ester; the preparation method comprises the following steps: carrying out nucleophilic substitution reaction on ethyl 5-methyl-5-hexenoate and bromoisopropane under the action of a basic catalyst to obtain ethyl 5-methyl-2-isopropyl-5-hexenoate; carrying out self Friedel-Crafts acylation reaction on the 5-methyl-2-isopropyl-5-hexenoic acid ethyl ester under the action of Lewis acid, so as to obtain 5-methyl-2-isopropyl-5-chloro cyclohexanone; and carrying out elimination reaction on the 5-methyl-2-isopropyl-5-chlorocyclohexanone under the action of alkali to obtain the product piperonone. According to the synthetic route, conventional chemical reagents are used as raw materials, reaction conditions are mild, emission of three wastes is reduced to a great extent, and the synthetic route is more environmentally friendly and suitable for continuous industrial production.

The invention discloses an acidic emulsified liquid seasoning, and relates to a low-calorie sesame-containing acidic emulsified liquid seasoning, and although the acidic emulsified liquid seasoning does not contain cane sugar, the strong and mellow sesame flavor can be felt. The present invention relates to an acidic emulsified liquid seasoning which does not contain sucrose and contains sesame, edible fat and oil, an emulsifier and a sour material. In addition, the acidic emulsion liquid seasoning according to the present invention is characterized by further comprising an ethyl 3-hexenoate (Ethyl 3-hexenoate).

The invention discloses a preparation method of 4-amino-5-hexenoic acid hydrochloride, and belongs to the technical field of medical intermediates. The preparation method comprises the following steps: by taking 1, 4-butanediol as a raw material, carrying out single protection on tert-butyldimethylsilyl chloride to obtain 4-(tert-butyldimethylsilyl) oxo-1-butanol, carrying out Swern oxidation reaction to obtain 4-(tert-butyldimethylsilyl) n-butyraldehyde, carrying out Schiff base reaction on the 4-(tert-butyldimethylsilyl) n-butyraldehyde and p-toluenesulfonamide to obtain 4-(tert-butyldimethylsilyl)-butyl-toluenesulfonamide, and carrying out reduced pressure distillation on the 4-(tert-butyldimethylsilyl)-butyl-toluenesulfonamide to obtain 4-(tert-butyldimethylsilyl)-butyl-toluenesulfonamide. The preparation method comprises the following steps: reacting tert-butyl (6-hydroxyhexane-1-ene-3-yl) carbamate with a vinyl Grignard reagent, performing deprotection / Boc protection to obtain tert-butyl (6-hydroxyhexane-1-ene-3-yl) carbamate, oxidizing the tert-butyl (6-hydroxyhexane-1-ene-3-yl) carbamate in the presence of a catalyst TEMPO to obtain Boc-4-amino-4-vinyl butyric acid, and finally performing hydrogen chloride deprotection to obtain 4-amino-5-hexenoic acid hydrochloride. The raw materials are easy to obtain and low in price, the requirement for equipment is not high, the process is coherent, the number of purification steps is small, and the obtained product is high in quality and meets the industrial production standard.

The present invention relates to sunscreen or daily care composition comprising (i) hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate (INCI diethylamino hydroxybenzoyl hexyl benzoate); and (ii) 1-(4-(1,1-dimethylethyl)phenyl)-3-(4-methoxyphenyl)propane-1,3-dione (INCI butyl methoxydibenzoylmethane); and (iii) 2,4-bis-{[4-(2-ethy-hexyoxy)-2-hydroxy]-pheny}-6-(4-methoxypheny)-1,3,5 triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine); and (iv) 4,4′,4″-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl)ester (INCI ethylhexyl triazone) and / or 4, 4′-[[6-[[4-[[(1,1-dimethylethyl)amino]carbonyl]phenyl]amino]-1,3,5-triazin-2,4-diyl]diimino]bis-benzoic acid-bis(2-ethylhexyl)ester (INCI diethyl-hexyl-butamidotriazone); and (v) at least one organic particulate UV filter, wherein the composition is free of ethylhexyl-2-cyano-3, 3-diphenyl-acrylate (INCI octocrylene), 2-ethylhexyl-(2E)-3-(4-methoxyphenyl) acrylate (INCI ethylhexyl methoxy cinnamate) and pp benzylidene malonates, and wherein the composition comprises diethylamino hydroxybenzoyl hexylbenzoate and butyl methoxydibenzoylmethane in a ratio of larger or equal to 0.8. Furthermore, the present invention relates to the use of said composition for the administration to sensitive skin. In addition, the present invention relates to the use of said composition to reduce sand adhesion after application of the composition on the skin.

The present invention provides a method for identifying the base of Chinese medicine Evodia rutaecarpa based on GC-IMS characteristic odor substances: the sample is subjected to headspace GC-IMS detection, and when the peak volume ratio of 2(E)-hexenoic acid, dimethyl disulfide, 3-methylthiopropanol and methyl 2-methoxybenzoate is 1:(1.4-2.0):(1.4-2.4):(1.7-2.6), it is Evodia rutaecarpa; when its ratio is 1:(0.4-0.9):(0.6-1.0):(0.6-1.2), it is sparse hair Evodia rutaecarpa or stone tiger; then, when the peak volume ratio of cyclopentanone and left-rotating carvone is 5.3-5.7, it is sparse hair Evodia rutaecarpa; when the ratio is 6.2-7.6, it is stone tiger. The method of the present invention is fast, non-destructive, does not require complex sample pre-treatment, is simple, environmentally friendly, has low detection cost, and has intuitive results. It is suitable for quickly, objectively and accurately judging the base of Chinese medicine Evodia rutaecarpa in batches.

The present invention provides a related substance of (3S)-3-(4-(3-(1,4-dioxaspiro[4,5]dec-7-en-8-yl)benzyloxy)phenyl)hex-4-inoic acid, and a method for evaluating the quality of (3S)-3-(4-(3-(1,4-dioxaspiro[4,5]dec-7-en yl)benzyloxy)phenyl)hex-4-inoic acid using the same. According to the present invention, it is possible to evaluate the quality, stability and the like of a pharmaceutical composition comprising (3S)-3-(4-(3-(1,4-dioxaspiro[4,5]dec-7-en-8-yl)benzyloxy)phenyl)hex-4-inoic acid using a compound of Chemical Formula 2 or a salt thereof as a reference standard.

To provide Areca catechu seed flavored products containing arecoline salts.SOLUTION: Arecoline salt is obtained by neutralizing arecoline with a compounding acid. The compounding acid is at least one of formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, capric acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, and the like. A product is an aerosol, chewing gum, or filter capsule.SELECTED DRAWING: None

The invention belongs to the technical field of organic synthesis, and discloses a rapid synthesis method of a beta-amino acid derivative. The method comprises the following steps: by taking an organic solvent as a reaction medium, reacting 3-hexenoic acid with a dioxazolone compound under the action of pinacolborane, a catalyst, silver salt and an alkaline compound to obtain the beta-amino acid derivative, the structure of the beta-amino acid derivative is as shown in formula I, and R is aryl, furyl, aryl-substituted alkenyl or 3, 4-methylenedioxy phenyl; the catalyst is a dichloro (pentamethyl cyclopentadienyl) rhodium (III) dimer; the organic solvent is a fluorine-containing alcohol solvent. The method has the advantages of mild reaction conditions, no need of nitrogen protection, one-step synthesis of the beta-amino acid derivative, and low energy consumption; the method provided by the invention has high chemical selectivity and high product yield. # imgabs0 #

The invention discloses pentaerythritol tetra (6-naphthyl hexanoic acid) ester and a preparation method and application thereof, the preparation method adopts two-step reaction of alkylation and esterification, the first step is that naphthalene and 5-hexenoic acid are subjected to alkylation reaction to generate 6-(1-naphthyl) hexanoic acid; and 2, carrying out a reaction on the 6-(1-naphthyl) hexanoic acid and thionyl chloride, and carrying out an esterification reaction with pentaerythritol to finally obtain the oily pentaerythritol tetra (6-naphthyl hexanoic acid) ester. The prepared pentaerythritol tetra (6-naphthyl hexanoate) ester has a structure with a symmetric four-arm core, a flexible alkyl chain and a rigid naphthalene end group, is shown as a formula (I), is used for lubrication and sealing of various equipment, and has the advantages of oxidation resistance, high and low temperature resistance, extreme pressure resistance, good lubrication and sealing performance and the like.

The present invention belongs to the field of biomedicine technology. It is a ceramide compound as shown in the chemical formula I: #imgabs0# wherein R 1 A residue selected from α-linolenic acid, γ-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, arachidonic acid, ximenynic acid, azelaic acid, jasmonic acid, threonic acid, 4-aminobutyric acid, erucic acid, glycolic acid, lactic acid, malic acid, tartaric acid, citric acid, lactobionic acid, rosmarinic acid, danshensu, sodium 3-(4-hydroxy-3-methoxyphenyl) lactate, p-hydroxyphenylacetic acid, palmitoleic acid, vitamin B5, vitamin H, ricinoleic acid, behenic acid, cis-11-eicosenoic acid, hexacosenoic acid-cis-17-enoic acid, cis-11,14-eicosadienoic acid, mandelic acid, or a condensation residue of a fruit acid, R 2 Select one of the following structures: -C 15 H 29 ,‑C 15 H 31 ,‑C 15 H 27 , ‑CHOHC 14 H 27 , ‑CHOHC 14 H 29 The present invention reacts a functional carboxylic acid with a sphingoid base to obtain a class of ceramide compounds with novel structures, thereby enhancing the original efficacy of such molecules and improving the physical and chemical properties of the ceramide compounds.

The present application relates to the field of analytical test technology, and particularly provides a reagent and method for separating and analyzing C=C double bond position isomerism based on crown ether, which comprises: separating and analyzing 2 / 3-butenoic acid (BA), 2 / 3 / 4-pentenoic acid (PA) and 2 / 3 / 5-hexenoic acid (HA) isomers respectively, mixing the above unsaturated isomers with crown ethers including 18 crown 6 (18C6), 15 crown 5 (15C5), 12 crown 4 (12C4) and divalent metal ions to form a mixed solution, and then separating and analyzing the mixed solution by means of ion mobility mass spectrometry. The ion mobility mass spectrometry experiment shows that the molecules can form ternary complexes of crown ether-isomer-metal ion through non-covalent interaction, and the C=C position isomerism can be simultaneously separated through the formed complexes. The analytical reagent and method provided by the present application are simple, accurate and fast in analysis speed, and do not need chemical derivatization, chromatographic separation and other previous steps, and the method can be used for separating different C=C double bond position isomers.

The invention belongs to the technical field of drug synthesis, and in particular to a method for preparing a milobalin intermediate (2E)-4-ethylheptyl-2,6-dienoic acid. Compound SM-1, i.e., (E)-2-hexenoic acid ester compounds, is reacted with allyl bromide as a raw material, and a target compound is obtained by post-processing. The reaction conditions of the present invention are mild, and the operating process is simple. The complex operation problems such as high temperature or long-term reaction and preparation of iminium salts in the prior art are solved, and the product has high purity and yield.

The embodiment of the invention provides a preparation method of cis-3-hexenoic acid butyl ester and application of the cis-3-hexenoic acid butyl ester. The preparation method comprises the following steps: dissolving butyl sorbate in an organic solvent to obtain an organic solution; the method comprises the following steps: dispersing a Pd-Mg / Al2O3 catalyst in water to obtain an aqueous solution; mixing the organic solution with the aqueous solution, carrying out hydrogenation reaction in a hydrogen atmosphere, standing after the reaction to layer the mixed system, and collecting an organic phase; and carrying out purification treatment on the organic phase to obtain the cis-3-hexenoic acid butyl ester, wherein the Pd-Mg / Al2O3 catalyst is prepared from an Mg-Al2O3 carrier and Pd nano particles which are loaded on the carrier, and the Pd nano particles are loaded on the Mg-Al2O3 carrier. The cis-3-butyl hexenoate prepared by the embodiment of the invention has higher yield and / or purity, which prompts that the embodiment of the invention has important significance in industrial production of the cis-3-butyl hexenoate.

The invention discloses an acidic emulsified liquid seasoning, and relates to a low-calorie sesame-containing acidic emulsified liquid seasoning, and although the calorie of the acidic emulsified liquid seasoning is low, the strong and mellow sesame flavor can be felt. The present invention relates to an acidic emulsified liquid seasoning having a calorie of 230 kcal / 100 g or less and containing sesame, edible fat and oil, an emulsifier, and a sour material. In addition, the acidic emulsified liquid seasoning according to the present invention is characterized by further comprising an ethyl 3-hexenoate (Ethyl 3-hexenoate).

We aim to provide a beverage that improves the balance between the characteristics of red grapes and the intensity of sweetness. [Solution] The red grape-flavored beverage of the present invention has an ethyl 3-hexenoate concentration of 0.25 to 6.0 ppb.