32 results about "Isobutyrates" patented technology

The invention provides a PHA dispersion emulsion as well as a preparation method and application thereof, and belongs to the field of high polymer materials. The invention aims to solve the technical problem that the prior art cannot simultaneously meet the requirements of the polyhydroxyalkanoate water dispersion system on extremely low temperature natural film-forming property, excellent comprehensive performance after film formation and long-term storage stability. The method is characterized in that a polyhydroxyalkanoate polymer with specific molecular weight and polydispersity index range, a coalescing agent 2, 2, 4-trimethyl-1, 3-pentanediol monoisobutyrate with a specific chemical structure and a specific type of aliphatic polyisocyanate cross-linking agent compatible with water dispersion are strictly limited and combined. Through the synergistic effect generated by the unique ternary combination, the minimum film forming temperature of the prepared emulsion can be reduced to 6-10 DEG C, a film can be naturally formed without hot pressing, and the formed film has excellent mechanical property, water resistance and adhesive force and has excellent storage stability of at least one year.

The invention discloses mongolian mongolian yeast and an application thereof. Relates to the technical field of fermentation. The invention provides a specific strain and application thereof in tobacco leaves. According to the tobacco leaf extracting solution fermented by the bacterial strain, the content of esters such as 2, 2, 4-trimethyl-1, 3-pentanediol monoisobutyrate, tributyl phosphate, dihydroactinidiolide, dibutyl phthalate, 3-(3, 5-di-tert-butyl-4-hydroxyphenyl) methyl propionate and methyl palmitate is remarkably increased, and the content of the esters such as 2, 2, 4-trimethyl-1, 3-pentanediol monoisobutyrate, tributyl phosphate, dihydroactinidiolide, dibutyl phthalate, 3-(3, 5-di-tert-butyl-4-hydroxyphenyl) methyl propionate and methyl palmitate is remarkably increased; three novel ester substances with fruit fragrance, rosin and other characteristic fragrances are newly generated, and the overall fragrance style is remarkably enhanced. It is shown that the aroma-producing caribeckia mongolica yeast MC-5 fermented tobacco leaf extracting solution has good aroma-producing capacity, and through the combined effect of enzymolysis and fermentation, the aroma-producing caribeckia mongolica yeast MC-5 fermented tobacco leaf extracting solution is expected to play an important application value in the field of quality improvement and aroma enhancement of tobacco leaf raw materials.

The invention discloses issatchenkia orientalis and application thereof. Relates to the technical field of fermentation. The invention provides a specific strain and application thereof in reconstituted tobacco. According to the tobacco leaf extracting solution fermented by the bacterial strain, the content of esters such as 2, 2, 4-trimethylpentanediol isobutyl ester, 2, 2, 4-trimethyl-1, 3-pentanediol monoisobutyrate, tributyl phosphate and methyl palmitate is remarkably increased, eight novel ester substances with the characteristic aroma such as fruit aroma and rosin are newly generated, and the tobacco leaf extracting solution has the advantages that the content of the esters such as the 2, 2, 4-trimethylpentanediol isobutyl ester, the 2, 2, 4-trimethyl-1, 3-pentanediol monoisobutyrate, the tributyl phosphate and the methyl palmitate is increased; and the whole fragrance style is obviously enhanced. It is shown that the aroma-producing issatchenkia orientalis IO-1 fermented tobacco leaf extracting solution has good aroma-producing capacity, and through the combined effect of enzymolysis and fermentation, the extracting solution is expected to play an important application value in the field of reconstituted tobacco leaf raw material quality improvement.

The invention discloses an Apiotrichum loubieri gene and an application of the Apiotrichum loubieri gene. Relates to the technical field of fermentation. The invention provides a specific strain and application thereof in reconstituted tobacco. According to the tobacco leaf extracting solution fermented by the bacterial strain, the content of esters such as 2, 2, 4-trimethyl-1, 3-pentanediol monoisobutyrate, dimethyl phthalate, tributyl phosphate, dihydroactinidiolide and methyl palmitate is remarkably increased, and the content of the esters such as 2, 2, 4-trimethyl-1, 3-pentanediol monoisobutyrate, dimethyl phthalate, tributyl phosphate, dihydroactinidiolide and methyl palmitate is remarkably increased; nine novel ester substances with aromatic smell, fruit fragrance, flower fragrance and other characteristic aromas are newly generated, and four phenolic aroma components are newly added. And the whole fragrance style is obviously enhanced. It is shown that the aroma-producing Apiotrichum loubieri AL-4 fermented tobacco enzyme extracting solution has good aroma-producing capacity, and through the combined effect of enzymolysis and fermentation, the aroma-producing Apiotrichum loubieri AL-4 fermented tobacco enzyme extracting solution is expected to play an important application value in the field of reconstituted tobacco raw material quality improvement.

This disclosure relates to crystalline forms of 3-acyl-buprenorphine derivatives and sustained release injectable pharmaceutical compositions for treatment of opioid dependence, pain or depression, including an aqueous suspension of crystalline 3-acyl-buprenoprhine, or a pharmaceutically acceptable salt thereof, wherein the composition does not include an organic solvent, a polylactide polymer, a polyglycolide polymer, or a copolymer of polylactide and polyglycolide. This disclosure also includes 3-acyl-buprenoprhine or a pharmaceutically acceptable salt thereof prepared in a controlled release matrix, including poly(lactide-co-glycolide), sucrose acetoisobutyrate, lecithin, diolein and a combination of two or more thereof.

The present application relates to a kind of 2,2,4,4-tetramethyl-1,3-cyclobutanedione preparation method.The present application first mixes isobutyric anhydride, small molecule alcohol and organic acid and carries out high-temperature cracking, so that isobutyric anhydride in it is cracked to generate isobutyric acid and dimethyl ethylene ketone, and the isobutyric acid generated simultaneously is esterified with small molecule alcohol under the action of organic acid to generate isobutyrate;The product after cracking is separated, and dimethyl ethylene ketone is absorbed using the isobutyrate obtained by separation, and dimerization is obtained 2,2,4,4-tetramethyl-1,3-cyclobutanedione.The present application can obtain higher yield under the same operating load, reduce the generation of carbon deposition and the corrosion to equipment in the reaction process, long running cycle, and low equipment investment.

The present invention relates to an anhydrous cosmetic, preferably solid, comprising, in a physiologically acceptable medium, at least: - a lipophilic polycondensate of the polyamide type, - a compound promoting the adhesion of the composition to keratinous materials chosen in particular from the group consisting of: . copolymers of vinylpyrrolidone (VP) and alkenes comprising from 2 to 20 carbon atoms, . sugar esters, preferably sucrose acetate isobutyrate (SAIB), . branched esters of dextrin, . and mixtures thereof, - optionally in addition at least one coloring material, characterized in that it comprises a total wax content of less than 7% by weight, preferably less than or equal to 5% by weight, or even is wax-free.

This invention relates to the field of pneumatic tire manufacturing technology, and discloses a radial bicycle pneumatic tire comprising the following components by weight percentage: 30%-55% natural rubber, 13%-25% synthetic rubber, 2%-7% carbon nanotubes, 5%-9% diethylene vulcanizate, 3%-6% propylene glycol diisobutyrate, 2%-4% dibutyl dithiocarbamate, 0.3%-0.8% UV stabilizer, 1%-5% crack inhibitor, 2%-3.7% waterproofing agent, and 1.5%-2.6% diethylene vulcanizate; benzothiadiazole thione is present at 2%-3% by weight. Due to its design characteristics, radial tires exhibit superior wear resistance and shear strength. In contrast, bias-ply tires have a relatively shorter service life. The long lifespan of radial bicycle pneumatic tires reduces the frequency and cost of tire replacement, providing a more economical and reliable option.

The present invention relates to an insulating film composition for a ceramic heater silicon carbide substrate and, more specifically, comprises: a first agent comprising 30-50 wt% of glass frit, 20-40 wt% of aluminum oxide, 1-5 wt% of ethyl cellulose and 20-30 wt% of 3-hydroxy-2,2,4-trimethylpentyl isobutyrate; and a second agent comprising 20-50 wt% of glass frit, 8-15 wt% of ethyl cellulose, 0.5-2 wt% of aluminum oxide, 40-65 wt% of 3-hydroxy-2,2,4-trimethylpentyl isobutyrate and 0.1-1 wt% of dimethyl phthalate. A wafer-sized SiC substrate having a thickness of 2t or less, excellent insulating properties and minimized warpage can be manufactured using the insulating film composition for a ceramic heater silicon carbide substrate, of the present invention, and can be applied to a thick-film heater, and thus can maximize the productivity of a product produced using the heater.

The present invention relates to a cosmetic in the form of an emulsion comprising, in a physiologically acceptable medium, at least: - a lipophilic polycondensate of the polyamide type, - a compound promoting the adhesion of the composition to keratinous materials, chosen in particular from the group consisting of: . copolymers of vinylpyrrolidone (VP) and alkenes comprising from 2 to 20 carbon atoms, . sugar esters, preferably sucrose acetate isobutyrate (SAIB), . branched dextrin esters, . and mixtures thereof, - optionally, in addition, at least one coloring agent.

The invention belongs to the technical field of concrete curing agents, and particularly relates to a rain-wash-proof surface-enhanced concrete curing agent, a curing coating as well as a preparation method and application of the rain-wash-proof surface-enhanced concrete curing agent. The curing agent comprises a component A and a component B, wherein the component A comprises a reinforcing agent and a penetrating agent, and the reinforcing agent is formed by compounding aluminum sulfate and sodium aluminate according to the mass ratio of (2-3): 1; the component B comprises a film-forming polymer matrix, 2, 2, 4-trimethyl-1, 3-pentanediol monoisobutyrate, an organic waterproof component, sodium silicate, titanium dioxide and deionized water, and the organic waterproof component is formed by compounding isobutyltriethoxysilane and potassium methylsilicate according to the mass ratio of (1.5-2.5): 1. The curing agent forms a reinforcing layer and a waterproof layer through staged spraying, endows newly poured concrete with early rain wash resistance, and has excellent water retention, hydrophobicity and heat reflection performance.

The application discloses a modifier for modified polyester powder coating and a preparation method thereof. The powder coating comprises, by mass fraction, a film-forming acid component, an epoxy curing component, a modifier, 2,2,4-trimethyl-1,3-pentanediol diisobutyrate, an antioxidant, a hindered amine light stabilizer and triphenylphosphine; wherein the modifier is nano-silica composite particles modified by silanization, phosphorus-nitrogen-zinc-aluminum coordination and aromatic dianhydride surface reaction. The powder coating is prepared through pre-mixing, melt extrusion, tabletting, cooling, crushing and screening, and can form a coating layer through electrostatic spraying and heat curing. The application improves the dispersibility and interface bonding of nano-silica in a polyester-epoxy curing system, and improves the properties, gloss, impact resistance and adhesion of the coating layer.

The application provides a zirconium oxide slurry and a preparation method and application thereof. The zirconium oxide slurry is prepared by mixing the following components in mass fractions: 80-85% of zirconium oxide, 1.6-3.6% of a dispersing agent, 7.89-14.58% of a photosensitive resin, 1.97-6.25% of a diluent, and 0.1-0.25% of a photosensitive initiator; wherein the diluent is 2,2,4-trimethyl-1,3-pentanediol diisobutyrate. The zirconium oxide slurry prepared by the application has a solid content of 80-85%, and simultaneously has low viscosity (45 DEG C, 2.0-3.0 Pa·S) and fluidity; under the light curing printing debinding procedure, the green body with a large volume is not prone to interlayer cracks or other irregular cracks.

This invention belongs to the field of organic synthesis technology and relates to a method for preparing (S)-4-(2,4-difluorophenyl)-2-(hydroxymethyl)pent-4-en-1-yl isobutyrate. 2,4-Difluoroiodobenzene reacts sequentially with allyl alcohol and tert-butyl chloroformate to obtain 2-(2,4-difluorophenyl)allyl tert-butyl carbonate. Under the action of a palladium catalyst and Sadphos chiral phosphine ligand, the 2-(2,4-difluorophenyl)allyl tert-butyl carbonate undergoes alkylation and reduction to obtain (S)-4-(2,4-difluorophenyl)-2-(hydroxymethyl)pent-4-en-1-yl isobutyrate. This invention utilizes a palladium catalyst and Sadphos chiral phosphine ligand to precisely construct a chiral center in one step, achieving an enantioselectivity of up to 99.4% and an overall yield of 65-70%. The operation is simple, the catalyst is recyclable, significantly reducing production costs and making it suitable for industrial production.

This invention provides a PHA dispersion emulsion, its preparation method, and its applications, belonging to the field of polymer materials. This invention aims to solve the technical challenge of simultaneously achieving ultra-low temperature natural film-forming properties, excellent post-film-forming comprehensive performance, and long-term storage stability in polyhydroxyalkanoate (PHA) aqueous dispersion systems, which cannot be simultaneously satisfied by existing technologies. Its core lies in the strict definition and combination of a PHA polymer with a specific molecular weight and polydispersity index range, a film-forming aid with a specific chemical structure (2,2,4-trimethyl-1,3-pentanediol monoisobutyrate), and a specific type of water-dispersible compatible aliphatic polyisocyanate crosslinking agent. Through the synergistic effect generated by this unique ternary combination, the minimum film-forming temperature of the emulsion prepared by this invention can be reduced to 6℃~10℃, it can form a film naturally without hot pressing, and the film exhibits excellent mechanical properties, water resistance, and adhesion, as well as excellent storage stability for at least one year.

The present invention provides energy curable thixotropic compositions comprising low amounts of 2,2,4-trimethyl-1,3-pentanediol isobutyrate (Texanol); 2,2,4-trimethyl-1,3-pentanediol diisobutyrate (TXIB); or dipropylene glycol butyl ether (DPGBE mixes isomers), or combinations thereof. The addition of the selected solvents in amounts of about 0.5 wt % to 3 wt % reduced the low shear rate viscosity of the energy curable thixotropic compositions.

Described herein is a delivery system including a non-aqueous solvent, a stabilizing agent selected from the group consisting of ester gum, sucrose acetate isobutyrate, Neobee oil, sugar alcohol, fructose and mixtures thereof, a surfactant selected from the group consisting of sucrose monoester, lecithin, modified starch, and mixtures thereof, at least one of an acid, acid salt or sweetener, and an active ingredient, where the delivery system includes 15% by weight or less of water. Also described herein is a process for preparing the delivery system and a method of delivering and protecting an active ingredient.

The application provides a preparation process of an anti-virus drug monabiravir for treating COVID-19, which comprises adding a base, reacting 2'-3'-isopropylidene cytidine with isobutyric anhydride to obtain 5'-isobutyrate containing amide impurities; then treating the reaction mixture with p-toluenesulfonic acid monohydrate to deprotect the acetonide and obtain pure isobutyryl cytidine p-toluenesulfonic acid salt containing no amide impurities; converting the p-toluenesulfonic acid salt into a free base, and then reacting with hydroxylamine to obtain monabiravir.

The application provides a preparation of a hyperbranched polymer electrolyte in-situ initiated by a diaphragm and application thereof. The diaphragm is first grafted with bromo-isobutyric acid ester through acylation reaction by using the abundant hydroxyl groups on the surface of the cellulose diaphragm; then a precursor solution is obtained by mixing a polymer monomer A, a branching initiation monomer B, a catalyst, a ligand and a lithium salt electrolyte; finally, the grafted cellulose diaphragm is soaked in the precursor solution to make the grafted cellulose diaphragm swell fully, and the hyperbranched polymer electrolyte in-situ initiated by the diaphragm is obtained after in-situ thermal polymerization of the battery. The hyperbranched polymer electrolyte in-situ initiated by the diaphragm prepared by the method has the advantages of high safety, high room temperature ionic conductivity and excellent interface stability, and the hyperbranched polymer electrolyte also has the diaphragm function, thereby providing a new research idea and method for preparing a high-performance polymer electrolyte.

The invention provides a method for simultaneously preparing nonafluoroisobutyl ether and heptafluoroisobutyrate from bis (heptafluoroisopropyl) heptanone, i.e., the bis (heptafluoroisopropyl) heptanone and fluoroformate react under the catalytic action of alkali metal fluoride to obtain the nonafluoroisobutyl ether and the heptafluoroisobutyrate. The technical scheme provided by the invention has the following advantages: 1) the one-step reaction is realized for the first time to obtain the nonafluoroisobutyl ether and the heptafluoroisobutyrate; the process route is simplified, the equipment investment and the production complexity are reduced, and the technical economy is improved. And 2) compared with the existing nonafluoroisobutyl ether preparation technology, the method does not use a high-toxicity alkylating reagent dimethyl sulfate or diethyl sulfate, does not generate a large amount of difficult-to-treat and high-toxicity solid byproduct potassium methyl sulfate or potassium ethyl sulfate, and is safer and more reliable in process. 3) compared with the existing heptafluoroisobutyrate preparation technology, the technical scheme is simple in process, safe and reliable; the reaction selectivity is good, and byproducts are few; and the product is easy to separate and high in yield.

The invention relates to the field of organic synthesis, and particularly provides a method for preparing heptafluoroisobutyrate, which comprises the following steps: S1) carrying out ozone cracking reaction by using perfluoroolefin as a raw material, reacting the product with alcohol, and separating and purifying to obtain fluoroformate; and S2) reacting the fluoroformate with hexafluoropropylene under the catalytic action of fluoride salt to obtain the heptafluoroisobutyrate. The invention has the following beneficial effects: 1) the main raw materials are commercially available and low in price; 2) the ozone cracking reaction conditions of the perfluoroolefin are mild, and the conversion rate of raw materials and the yield of the product (fluoroformate) are high; 3) the fluoride salt only serves as a catalyst in the reaction of the fluoroformate and the hexafluoropropylene and is not used as a raw material, no solid by-product is generated in the process, and the product is easy to separate and purify; and 4) the whole production process is safe and reliable, and is suitable for industrial production.

The present invention relates to an anhydrous cosmetic composition comprising, in a physiologically acceptable medium, at least: (i) a polyamide lipophilic polycondensate, (ii) a compound promoting adhesion of the composition to keratin materials, chosen in particular from the group consisting of copolymers of vinylpyrrolidone (VP) and of alkene comprising from 2 to 20 carbon atoms, sugar esters, preferably sucrose acetate isobutyrate (SAIB), branched dextrin esters, and mixtures thereof, preferably sucrose acetate isobutyrate (SAIB), (iii) a volatile oil, and (iv) optionally in addition at least one colorant.

This invention belongs to the field of polymer material additive synthesis technology, specifically relating to a method for preparing a mixed environmentally friendly plasticizer base material rich in asymmetric esters, as well as the base material and the mixed environmentally friendly plasticizer. The method includes the following steps: (1) Preparation of esterification reactants: 2,2,4-trimethyl-1,3-pentanediol monoisobutyrate is mixed with benzoic acid, and an azeotropic dehydrating agent is added; (2) Addition of a composite reaction inhibition system: A composite Lewis acid catalyst and a binary composite antioxidant are added to the system; (3) Stepwise esterification and liquid-based gas stripping to remove water: An azeotropic dehydration reaction with stepwise temperature increase is carried out under a protective atmosphere; (4) Separation and purification: The crude reaction liquid obtained in step (3) is washed, and after removing light components, it is sent to a scraped film molecular evaporator for short-path distillation. The distillate on the condensation surface is collected to obtain the environmentally friendly plasticizer base material. This invention aims to improve the yield of asymmetric esters by combining the optimization of catalysts with the enhancement of hydrodynamic mass transfer.

This invention discloses a method for preparing chlorofibrate using sulfur hexafluoride (SF6). The method uses ethanol and p-chlorophenoxyisobutyric acid (p-chlorophenoxyisobutyric acid) as raw materials, with an alkaline substance as an additive. The reaction is carried out in a solvent under light irradiation in the presence of SF6 and a photocatalyst to obtain chlorofibrate. In this method, SF6 is activated under photocatalytic conditions, and the esterification reaction of p-chlorophenoxyisobutyric acid with SF6 decomposition products is achieved to obtain chlorofibrate. The SF6 decomposition products serve as a condensation reagent. This method effectively activates SF6, a greenhouse gas, and fully utilizes the SF6 decomposition products to achieve the esterification of p-chlorophenoxyisobutyric acid to obtain chlorofibrate, turning SF6 waste into a valuable resource. The raw materials required by this method are simple and readily available, the reaction conditions are simple, green, and energy-saving, and it has high application value.

The invention discloses a preparation method of medicinal pregnenolone isobutyrate, which comprises the following steps: (1) sequentially adding isobutyric acid (I), an organic solvent A and an acid-binding agent into a reaction container, uniformly stirring, dropwise adding an organic solvent A solution of an organic phosphorus condensing agent, and reacting to obtain a reaction solution containing an intermediate (II); (2) dropwise adding a pregnenolone (III) solution into the reaction solution, and reacting to obtain a reaction solution containing pregnenolone isobutyrate (IV); (3) filtering the reaction solution obtained in the step (2), concentrating under reduced pressure, dissolving, passing through a silica gel column, eluting with normal hexane / ethyl acetate, dripping a TLC plate, collecting eluent containing pregnenolone isobutyrate, and concentrating under reduced pressure to obtain concentrated solution; (4) adding an organic solvent B, uniformly stirring, and filtering to obtain a filter cake; (5) washing a filter cake, and drying to obtain medicinal pregnenolone isobutyrate (IV); the method has the advantages of high safety, easily available raw materials, low production cost, high yield and small environmental pollution.

The invention provides a saline-alkali soil Fusarium oxysporum and application thereof, belongs to the technical field of development and utilization of microbial resources, and aims to solve the problems of high cost, low repeatability, lack of wild strains capable of efficiently synthesizing higher alcohols and the like in a higher alcohol chemical synthesis process. The invention provides a strain capable of efficiently fermenting and synthesizing various higher alcohols such as isoamyl alcohol, 2-methyl butanol, n-hexyl alcohol, n-propyl alcohol, sec-octyl alcohol, isobutanol, alpha-acorus calamus alcohol, phenethyl alcohol and the like, as well as ethyl acetate, isoamyl acetate, 2, 2, 4-trimethyl-1, 3, 4-triazole-1, 3-dione, 2, 3, 4-triazole-1, 3-dione and 2, 3, 4-triazole-1, 3-dione by utilizing PDA culture medium components. The invention relates to a salt-resistant, acid-resistant and alkali-resistant fungus strain KKFV1024 (Fusarium aromatic) of ester compounds such as 1, 3-pentanediol diisobutyrate, hexyl acetate, 2-methylbutyl acetate, ethyl phenylacetate and the like. The strain provided by the invention not only can effectively synthesize various higher alcohols and ester compounds, but also is short in fermentation time, low in cost, simple to operate and reusable.

The application discloses a kind of ceramic glaze and the method for preparing ceramic product with it, belong to the technical field of ceramics.Ceramic glaze includes the following components: kaolin, calcined talc, potassium feldspar, limestone, barium carbonate, yttrium oxide, nepheline syenite, 2,2,4-trimethyl-1,3-pentanediol monoisobutyrate and tetramethyldihydrodisiloxane.The prepared ceramic product can reach GLA level in low concentration acid and alkali resistance, at the same time, can reach more than 5500 revolutions in abrasion resistance test, gloss reaches more than 88°, and the overall glaze surface color is uniform.

The present invention relates to an anhydrous cosmetic composition comprising, in a physiologically acceptable medium, at least: (i) a lipophilic polycondensate of the polyamide type, (ii) a compound promoting the adhesion of the composition to keratinous materials, selected in particular from the group consisting of vinylpyrrolidone (VP) and alkene copolymers comprising 2 to 20 carbon atoms, sugar esters, preferably sucrose acetate isobutyrate (SAIB), branched dextrin esters, and mixtures thereof, preferably sucrose acetate isobutyrate (SAIB), (iii) a volatile oil, and (iv) optionally, in addition, at least one colorant. Figure: none

The present invention provides a perfume composition containing a compound represented by the formula (1) as an active ingredient. (In formula (1), R1 represents a C2-4 linear or branched olefinic unsaturated hydrocarbon group, and R2 represents a C1-6 linear, branched, or cyclic alkyl group.)