Erigeron breviscapus extraction dry suspensoid agent

A technology of breviscapine and dry suspension, which is applied in powder delivery, cardiovascular system diseases, organic active ingredients, etc., and can solve the problems of poor patient compliance, poor bioavailability, poor water solubility and fat solubility, etc. Achieve good redispersibility, slow settling rate and good fluidity
CN1559424AInactive Publication Date: 2005-01-05FUDAN UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
FUDAN UNIV
Publication Date
2005-01-05
Estimated Expiration
Not applicable · inactive patent

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Abstract

A dried suspension for treating cardiovascular and cerebrovascular diseases is prepared from breviscapine, filler, suspending aid, flowing aid, lubricant and flavouring through drying, pulverizing and proportional mixing. It is mixed with water before used.
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Description

technical field

[0001] The invention belongs to the field of pharmaceutical preparations, and relates to a pharmaceutical preparation for treating cardiovascular and cerebrovascular diseases. It specifically relates to a dry suspension containing breviscapine. Background technique

[0002] Brevescapine (Brevescapine) is a class of flavonoids isolated from the Asteraceae plant (formerly known as Dengzhanhua, also known as Dengzhan Asarum, Erigeron Breviscapus (Vant.) Hand.-Mazz.), mainly containing Scutellarin (chemical name 4', 5, 6-trihydroxyflavonoid-7-glucuronide) also contains a small amount of scutellarin and other flavonoids.

[0003] Existing pharmacodynamic studies have shown that breviscapine can dilate cerebral blood vessels, reduce cerebrovascular resistance, increase cerebral blood flow, improve microcirculation, improve blood-brain barrier permeability, enhance the phagocytic immune function of macrophages, and fight against the pituitary gland. Vasoline-induc...

Claims

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