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Imaging type biological chip instrument

A biochip and chip instrument technology, applied in the direction of material excitation analysis, fluorescence/phosphorescence, etc., can solve the problems of poor analysis sensitivity, poor excitation efficiency of white light source, and long time consumption, etc., and achieve the effect of reducing analysis time

Inactive Publication Date: 2005-03-16
KAIWOOD TECH
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AI Technical Summary

Problems solved by technology

Although this kind of biochip instrument does not need to scan the sample points one by one, but because the excitation efficiency of the white light source is poor, its analytical sensitivity is not as good as the aforementioned type of biochip instrument
If you want to improve the analytical sensitivity, it still takes a long time to get a higher fluorescent signal value

Method used

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  • Imaging type biological chip instrument
  • Imaging type biological chip instrument
  • Imaging type biological chip instrument

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Embodiment Construction

[0026] image 3 It is an embodiment of the imaging biochip instrument 5 of the present invention. image 3 The shown biochip array analyzer 5 comprises a light source 5) for sending light beams; a collimating lens 51 makes the light beams sent by the light source form a large area of ​​parallel light, and this parallel light passes through the biochip 52 to make the biochip The fluorescent substance on the 52 is excited to produce fluorescent light; a focusing lens 53 is used to focus the fluorescent light; a filter 54 is used to filter out interfering light waves; a CCD camera 55 with a large lens is used to focus the fluorescent light The signal is selected as an image; a carrying platform 57 for carrying the biochip 52; and an image data conversion device 56, which can convert the image signal into data, so as to judge and read the fluorescence intensity of each analysis sample point.

[0027] When using the imaging biochip instrument of the present invention to analyze bi...

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Abstract

This invention provides a visualization biological chip device which at least comprises the following: a light source to send out light beam; a calibration lens to let the light source send out parallel light of large area which goes through the biological chip and makes the fluorescence material on the biological chip send out fluorescence; a focus lens to focus fluorescence; a filter sheet to filter the interference light wave; a CCD cameral to select the fluorescence signals into images which is translated into data through a image-digit translation device to judge and read the fluorescence light intensity. The visualization biological chip in this invention can make the sample simultaneously accept the high efficiency laser source and uses CCD cameral select the fluorescence image of the biological chip rapidly with large area for further analysis.

Description

technical field [0001] The invention relates to a biological chip reading device, in particular to a device which uses a CCD (Charge-Coupled Device, Charge-Coupled Device) camera to select an image and then analyze it. Background technique [0002] At present, there are many analytical tools or analytical methods that can be used to detect biomolecules such as nucleic acids or proteins, but these analytical methods often take a long time to obtain the analysis results when analyzing a large number of samples. Furthermore, when analyzing a large number of samples, it is often impossible to complete the same analysis due to too many samples, thus easily causing errors in the analysis data. For the study of gene body and protein body, it is often necessary to analyze and compare a large number of samples at the same time, and the existing analysis methods can no longer meet the needs, so more efficient analysis tools are needed. [0003] Biochips are attracting attention due t...

Claims

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Application Information

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IPC IPC(8): G01N21/62G01N21/64
Inventor 王建华吴自强庄建和庄琮凯
Owner KAIWOOD TECH
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