Drop pills of clearing away heat and toxic material for anti parotitis and preparing method

A technology for mumps and mumps, applied in anti-mumps dropping pills for clearing away heat and detoxification and its preparation field, can solve the problems of unfavorable social overall health level, heavy economic burden of patients, low dissolution rate, etc. Protection and environmental protection, enhanced bioavailability, accelerated dissolution and absorption effects

Inactive Publication Date: 2005-08-31
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Due to the limitation of existing injection preparation technology and the influence of the complexity of traditional Chinese medicine ingredients, traditional Chinese medicine injections are often prone to acute allergic reactions or adverse reactions, and there are also difficulties in operation, great pain for patients, high manufacturing and medical costs, and inconvenient transportation and storage. , heavy financial burden for patients, unsuitable for family use and other disadvantages
[0007] In addition, due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicines, have long dissolution time, low dissolution rate, poor absorption, hepatic first-pass effect and low bioavailability after taking. and other issues, thus affecting the efficacy of the drug, and directly affecting the therapeutic effect
At the same time, conventional oral dosage forms often produce relatively large dust pollution during the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause certain pollution to the environment.
The production process of conventional oral preparations is also relatively complicated, and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0028] Now with several groups of specific examples, the preparation method of the anti-mumps dropping pills of the present invention will be further described.

[0029] Group 1: Tests with a single matrix

[0030] 1. Preparation of the drug extract: Prepare according to the preparation method 1, and prepare the dry powder of the extract containing the active ingredient of the traditional Chinese medicine Lonicerae vine for future use;

[0031] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. One or a mixture of two or more pharmaceutical carriers;

[0032] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0033] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain anti-mumps dropping pills of different specifications.

[00...

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PUM

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Abstract

A Chinese medicine in the form of dripping pill for treating mumps, infantile cold, fever, rubella, herpes, etc is prepared from honeysuckle stem and matrix.

Description

technical field [0001] The present invention relates to a kind of medicinal composition which has heat-clearing, detoxifying and meridian dredging effects, and is used for treating mumps, infantile cold and fever caused by internal heat and exogenous pathogenic factors, and infantile cold accompanied by rubella and herpes. An oral preparation of a pharmaceutical composition prepared from rattan as a raw material. Background technique [0002] According to the ministerial drug standard WS 3 -The anti-mumps injection prepared by the preparation method given in B-3843-98 is a kind of anti-mumps injection that has the functions of clearing away heat, detoxifying and dredging collaterals, and is used for the treatment of mumps, children's cold, fever and other diseases caused by internal heat and external pathogens. The pure traditional Chinese medicine injection for children with rubella, herpes and other diseases has been clinically proven to be effective, and it is a commonly...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61P31/12
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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